Page last updated: 2024-10-20

pyridoxine and Venous Thrombosis

pyridoxine has been researched along with Venous Thrombosis in 5 studies

4,5-bis(hydroxymethyl)-2-methylpyridin-3-ol: structure in first source
vitamin B6 : Any member of the group of pyridines that exhibit biological activity against vitamin B6 deficiency. Vitamin B6 deficiency is associated with microcytic anemia, electroencephalographic abnormalities, dermatitis with cheilosis (scaling on the lips and cracks at the corners of the mouth) and glossitis (swollen tongue), depression and confusion, and weakened immune function. Vitamin B6 consists of the vitamers pyridoxine, pyridoxal, and pyridoxamine and their respective 5'-phosphate esters (and includes their corresponding ionized and salt forms).

Venous Thrombosis: The formation or presence of a blood clot (THROMBUS) within a vein.

Research Excerpts

ExcerptRelevanceReference
"The Vitamins and Thrombosis (VITRO) study investigated the effect of homocysteine lowering by daily supplementation of B vitamins on the risk reduction of deep vein thrombosis (DVT) and pulmonary embolism (PE)."9.12Homocysteine lowering by B vitamins and the secondary prevention of deep vein thrombosis and pulmonary embolism: A randomized, placebo-controlled, double-blind trial. ( Blom, HJ; Bos, GM; Cattaneo, M; den Heijer, M; Eichinger, S; Gerrits, WB; Rosendaal, FR; Willems, HP, 2007)
"In recent years research was done to elucidate the relation between an increased homocysteine concentration and arterial as well as venous thrombosis."8.80[Hyperhomocysteinemia as a risk factor for venous thrombosis]. ( Blom, HJ; Bos, GM; den Heijer, M; Gerrits, WB; Rosendaal, FR; Willems, HP, 1999)
"The Vitamins and Thrombosis (VITRO) study investigated the effect of homocysteine lowering by daily supplementation of B vitamins on the risk reduction of deep vein thrombosis (DVT) and pulmonary embolism (PE)."5.12Homocysteine lowering by B vitamins and the secondary prevention of deep vein thrombosis and pulmonary embolism: A randomized, placebo-controlled, double-blind trial. ( Blom, HJ; Bos, GM; Cattaneo, M; den Heijer, M; Eichinger, S; Gerrits, WB; Rosendaal, FR; Willems, HP, 2007)
"In recent years research was done to elucidate the relation between an increased homocysteine concentration and arterial as well as venous thrombosis."4.80[Hyperhomocysteinemia as a risk factor for venous thrombosis]. ( Blom, HJ; Bos, GM; den Heijer, M; Gerrits, WB; Rosendaal, FR; Willems, HP, 1999)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (40.00)18.2507
2000's3 (60.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
den Heijer, M3
Willems, HP3
Blom, HJ2
Gerrits, WB2
Cattaneo, M1
Eichinger, S1
Rosendaal, FR2
Bos, GM3
Rodrigues, CA1
Morelli, VM1
DA Silveira, RC1
D'Almeida, V1
Lourenço, DM1
Lubbers, MF1
Aarnoudse, JG1
van Doormaal, JJ1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Homocysteine Lowering by B Vitamins and the Secondary Prevention of Deep-Vein Thrombosis and Pulmonary Embolism. A Randomized, Placebo-Controlled, Double Blind Trial.[NCT00314990]620 participants Interventional1996-01-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for pyridoxine and Venous Thrombosis

ArticleYear
[Hyperhomocysteinemia as a risk factor for venous thrombosis].
    Nederlands tijdschrift voor geneeskunde, 1999, Mar-13, Volume: 143, Issue:11

    Topics: Adult; Aged; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Pros

1999

Trials

3 trials available for pyridoxine and Venous Thrombosis

ArticleYear
Homocysteine lowering by B vitamins and the secondary prevention of deep vein thrombosis and pulmonary embolism: A randomized, placebo-controlled, double-blind trial.
    Blood, 2007, Jan-01, Volume: 109, Issue:1

    Topics: Adolescent; Adult; Aged; Dose-Response Relationship, Drug; Double-Blind Method; Female; Folic Acid;

2007
Homocysteine reduction by B-vitamin supplementation increases t-PA and PAI-1 levels in patients with venous thromboembolism.
    Journal of thrombosis and haemostasis : JTH, 2007, Volume: 5, Issue:1

    Topics: Adolescent; Adult; Aged; Dietary Supplements; Double-Blind Method; Drug Combinations; Endothelium, V

2007
Homocysteine and venous thrombosis: outline of a vitamin intervention trial.
    Seminars in thrombosis and hemostasis, 2000, Volume: 26, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Comorbidity; Double-Blind Method; Female; Folic Acid; Follow-Up Stud

2000

Other Studies

1 other study available for pyridoxine and Venous Thrombosis

ArticleYear
[Obstetric problems followed by stroke].
    Nederlands tijdschrift voor geneeskunde, 1999, Apr-03, Volume: 143, Issue:14

    Topics: Abortion, Habitual; Adult; Arteriosclerosis; Cerebral Infarction; Diagnosis, Differential; Female; F

1999