pyridoxine and Urinary Calculi studies

4,5-bis(hydroxymethyl)-2-methylpyridin-3-ol: structure in first source
vitamin B6 : Any member of the group of pyridines that exhibit biological activity against vitamin B6 deficiency. Vitamin B6 deficiency is associated with microcytic anemia, electroencephalographic abnormalities, dermatitis with cheilosis (scaling on the lips and cracks at the corners of the mouth) and glossitis (swollen tongue), depression and confusion, and weakened immune function. Vitamin B6 consists of the vitamers pyridoxine, pyridoxal, and pyridoxamine and their respective 5'-phosphate esters (and includes their corresponding ionized and salt forms).

Urinary Calculi: Low-density crystals or stones in any part of the URINARY TRACT. Their chemical compositions often include CALCIUM OXALATE, magnesium ammonium phosphate (struvite), CYSTINE, or URIC ACID.

Research Excerpts

Excerpt	Relevance	Reference
"To examine the effects of dietary manipulation and pyridoxine medical management for idiopathic hyperoxaluria in patients with nephrolithiasis."	7.77	Pyridoxine and dietary counseling for the management of idiopathic hyperoxaluria in stone-forming patients. ( Kriedberg, C; Miyaoka, R; Moeding, A; Monga, M; Ortiz-Alvarado, O; Stessman, M, 2011)
"Urinary excretion of 4-pyridoxic acid and oxalic acid was investigated in 75 patients with urinary calculi and in 50 normal subjects on regular diet."	7.65	Excretion of 4-pyridoxic acid and oxalic acid in patients with urinary calculi. ( Tiselius, HG, 1977)
"To examine the effects of dietary manipulation and pyridoxine medical management for idiopathic hyperoxaluria in patients with nephrolithiasis."	3.77	Pyridoxine and dietary counseling for the management of idiopathic hyperoxaluria in stone-forming patients. ( Kriedberg, C; Miyaoka, R; Moeding, A; Monga, M; Ortiz-Alvarado, O; Stessman, M, 2011)
"Urinary calculi composed of calcium oxalate were produced in male hooded Wistar rats fed a vitamin B6 deficient diet over 16 weeks."	3.66	Experimental oxalate urolith formation in rats. ( Belling, GB; Bulman, FH; McIntosh, GH, 1979)
"Urinary excretion of 4-pyridoxic acid and oxalic acid was investigated in 75 patients with urinary calculi and in 50 normal subjects on regular diet."	3.65	Excretion of 4-pyridoxic acid and oxalic acid in patients with urinary calculi. ( Tiselius, HG, 1977)
" Stone prevention is based on drug withdrawal or change in dosage with additional measures including an increase of diuresis and, if necessary, changes in the urine pH."	2.40	[Drug-induced urinary calculi in 1999]. ( Daudon, M, 1999)
" The dosage schedule of these patients was recorded."	1.35	Drug dosage protocol for calcium oxalate stone. ( Marickar, YM; Salim, A, 2009)
"Treatment with lupeol and lupeol linoleate reduced the extent of tubular damage as evidenced from reduced enzymuria and minimized the excretion of stone forming constituents."	1.31	Evaluation of the effect of triterpenes on urinary risk factors of stone formation in pyridoxine deficient hyperoxaluric rats. ( Lenin, M; Varalakshmi, P; Vidya, L, 2002)
"Pyridoxilate is a salt formed from glyoxylic acid and pyridoxine."	1.27	[Calcium oxalate stones and hyperoxaluria secondary to treatment with pyridoxilate]. ( Arvis, G; Barthélémy, C; Maistre-Charransol, G; Steg, A; Thomas, E; Thomas, J; Wolf, C, 1985)

Research

Studies (61)

Authors

Clinical Trials (1)

Trial Overview

Trial Outcomes

Change in Sequential Organ Failure Assessment (SOFA) Score

Timeframe	Studies, this research(%)	All Research%
pre-1990	50 (81.97)	18.7374
1990's	7 (11.48)	18.2507
2000's	3 (4.92)	29.6817
2010's	1 (1.64)	24.3611
2020's	0 (0.00)	2.80

Authors	Studies
Marickar, YM	1
Salim, A	1
Ortiz-Alvarado, O	1
Miyaoka, R	1
Kriedberg, C	1
Moeding, A	1
Stessman, M	1
Monga, M	1
Vidya, L	1
Lenin, M	1
Varalakshmi, P	1
Rosdy, E	1
Kiss, T	1
Török, P	1
Baán, L	1
Jancsó, T	1
Ficsor, E	1
Makáry, G	1
Walter, G	1
Harrison, AR	1
Kasidas, GP	1
Rose, GA	2
Ringsdorf, WM	1
Cheraskin, E	1
Murthy, MS	1
Farooqui, S	1
Talwar, HS	1
Thind, SK	3
Nath, R	3
Rajendran, L	1
Bapna, BC	1
Kondás, J	1
Gyarmathy, F	1
Molnár, I	1
Baranyai, E	2
Kis, E	2
Szebeni, R	3
Asper, R	1
Rattan, V	1
Sidhu, H	2
Vaidyanathan, S	1
Oner, A	1
Demircin, G	1
Ipekçioğlu, H	1
Bülbül, M	1
Ecin, N	1
Bren, A	1
Kmetec, A	1
Kveder, R	1
Kaplan-Pavlovcic, S	1
Daudon, M	3
Assimos, DG	1
Holmes, RP	1
Frang, D	6
Szendröi, Z	1
Revúsová, V	2
Gratzlová, J	1
Zvara, V	2
Krídl, J	2
Suchánek, B	1
Grühn, E	1
Elmadfa, I	1
McIntosh, GH	1
Belling, GB	1
Bulman, FH	1
Matouschek, E	1
Huber, R	1
Tiselius, HG	2
Almgård, LE	1
Berényi, M	4
Babics, A	3
Scheinman, JI	1
Edwards, P	1
Nemat, S	1
Bataille, P	1
Finet, M	1
Renaud, H	1
Fievet, P	1
Rogez, JC	1
Fournier, A	1
Teillac, P	1
de Dreuzy, O	1
Nguyen, HV	1
Reveillaud, RJ	1
Le Duc, A	1
Khanam, A	1
Rahman, B	1
Rahman, MA	1
Ondrus, B	1
Reveilland, RJ	1
Jungers, P	1
Gulati, S	1
Narula, R	1
Sadhna, S	1
Wangoo, D	1
Singhal, GD	1
Singh, DN	1
Gopal, SC	1
Ambasta, SS	1
Gupta, RM	1
el-Habet, AE	1
el-Sewedy, SM	1
el-Sharaky, A	1
Gaafar, NK	1
Abdel-Rafee, A	1
Hamoud, F	1
Reis-Santos, JM	1
Guimarães, P	1
Correia, R	1
Ferreira, AM	1
Wolf, C	2
Maistre-Charransol, G	2
Barthélémy, C	2
Thomas, E	2
Thomas, J	2
Arvis, G	1
Steg, A	1
Ottavioli, JN	1
Böwering, R	1
Sutor, DJ	1
Prien, EL	1
Gershoff, SF	1
Renke, W	1
Kasztelan, Z	1
Winnicka, A	1
Terhorst, B	2
Lutzeyer, W	1
Frimpter, GW	1
Oleĭnik, IuS	1
Chow, FH	1
Hamar, DW	1
Udall, RH	1
Malm, OJ	1
Melchior, H	1
Zinsser, HH	1
Stern, F	1
Marshall, S	1
Karp, F	1
Seneca, E	1
Gursel, E	1
Gershoff, SN	1
Yachiku, S	1
Okawa, T	1
Takeuchi, M	1
Sonoda, T	1
Ljunggren, E	1
Berariu, T	1
Băltescu, V	1
Proinov, I	1
Cătană, R	1
Palagiano, V	1

Trial	Phase	Enrollment	Study Type	Start Date	Status
Outcomes of Metabolic Resuscitation Using Ascorbic Acid, Thiamine, and Glucocorticoids in the Early Treatment of Sepsis.[NCT03422159]	Phase 2	140 participants (Actual)	Interventional	2018-02-05	Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Defined as the day 4 post-randomization SOFA score minus the initial SOFA score. The Sequential Organ Failure Assessment (SOFA) Score is a mortality prediction score that is based on the degree of dysfunction of six organ systems. The score is calculated on admission and every 24 hours until discharge using the worst parameters measured during the prior 24 hours SOFA score ranges from 0 (no organ dysfunction) to 24 (highest possible score / organ dysfunction). (NCT03422159)
Timeframe: 4 days post-randomization

Hospital Length of Stay

Intervention	score on a scale (Mean)
Treatment Arm	2.9
Placebo Arm	1.93

Time from admitting to discharge of hospital stay. (NCT03422159)
Timeframe: From admission to the hospital until final discharge, up to 28 days.

Hospital Mortality

Intervention	Days (Mean)
Treatment Arm	11.5
Placebo Arm	11

In-hospital mortality rate. (NCT03422159)
Timeframe: Survival until hospital discharge, up to 28 days.

ICU Length of Stay

Intervention	Participants (Count of Participants)
Treatment Arm	11
Placebo Arm	13

Time from admitting to ICU to discharge. (NCT03422159)
Timeframe: From admission to the ICU until final discharge from the ICU, up to an average of 7 days.

ICU Mortality

Intervention	days (Mean)
Treatment Arm	4.76
Placebo Arm	4.66

ICU mortality rate (NCT03422159)
Timeframe: From admission to hospital until final discharge from the ICU, up to 28 days.

Procalcitonin (PCT) Clearance

Intervention	Participants (Count of Participants)
Treatment Arm	6
Placebo Arm	10

PCT at 96 hours minus initial PCT, divided by the initial PCT multiplied by 100. (NCT03422159)
Timeframe: 4 days post-randomization

Time to Vasopressor Independence (Hours)

Intervention	Percent (Mean)
Treatment Arm	63
Placebo Arm	58

Defined as the time from starting the active treatment/placebo to discontinuation of all pressors. (NCT03422159)
Timeframe: From start of vasopressor medication to final discontinuation of vasopressor medication, up to 7 days.

Ventilator Free Days

Intervention	hours (Mean)
HAT Treatment	27
Comparator	53

Number of days alive and off of the ventilator at day 28. (NCT03422159)
Timeframe: 28 Days post-randomization

Article	Year
Nutritional aspects of urolithiasis. Southern medical journal, 1981, Volume: 74, Issue:1 Topics: Adult; Ascorbic Acid; Calcium Oxalate; Diet; Humans; Magnesium; Male; Nutritional Physiological Phen	1981
[Drug-induced urinary calculi in 1999]. Progres en urologie : journal de l'Association francaise d'urologie et de la Societe francaise d'urologie, 1999, Volume: 9, Issue:6 Topics: Acetazolamide; Allopurinol; Aluminum Hydroxide; Calcium; Cathartics; Diuretics; HIV Protease Inhibit	1999
Role of diet in the therapy of urolithiasis. The Urologic clinics of North America, 2000, Volume: 27, Issue:2 Topics: Ascorbic Acid; Calcium; Dietary Carbohydrates; Dietary Fats; Dietary Fiber; Dietary Proteins; Humans	2000
Magnesium oxide-pyridoxine therapy for recurrent urolithiasis. Nutrition reviews, 1976, Volume: 34, Issue:1 Topics: Animals; Calcium Phosphates; Humans; Magnesium Deficiency; Magnesium Oxide; Male; Oxalates; Pyridoxi	1976
[Medical treatment of idiopathic calcium lithiasis (II)]. Nephrologie, 1985, Volume: 6, Issue:4 Topics: Allopurinol; Benzothiadiazines; Calcium; Cellulose; Citrates; Citric Acid; Diuretics; Humans; Magnes	1985
Role of vitamins in urolithiasis. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 1988, Volume: 42, Issue:9 Topics: Adult; Ascorbic Acid; Glycine; Humans; Pyridoxine; Tryptophan; Urinary Calculi; Vitamin A; Vitamins	1988
Sex hormones, vitamin B6, and formation of urinary calculi in rats. Nutrition reviews, 1970, Volume: 28, Issue:7 Topics: Animals; Castration; Female; Gonadal Steroid Hormones; Male; Pyridoxine; Rats; Sex Factors; Testoste	1970

Article	Year
Drug dosage protocol for calcium oxalate stone. Urological research, 2009, Volume: 37, Issue:6 Topics: Allopurinol; Antimetabolites; Calcium Oxalate; Dose-Response Relationship, Drug; Drug Therapy, Combi	2009
Pyridoxine and dietary counseling for the management of idiopathic hyperoxaluria in stone-forming patients. Urology, 2011, Volume: 77, Issue:5 Topics: Combined Modality Therapy; Directive Counseling; Female; Humans; Hyperoxaluria; Longitudinal Studies	2011
Evaluation of the effect of triterpenes on urinary risk factors of stone formation in pyridoxine deficient hyperoxaluric rats. Phytotherapy research : PTR, 2002, Volume: 16, Issue:6 Topics: Acetylglucosaminidase; Alkaline Phosphatase; Animals; Calcium; Calcium Oxalate; gamma-Glutamyltransf	2002
Observations with Magurlit in the treatment of patients with uric acid stone. Therapia Hungarica (English edition), 1984, Volume: 32, Issue:2 Topics: Adult; Aged; Citrates; Drug Combinations; Female; Humans; Male; Middle Aged; Pyridoxine; Uric Acid;	1984
Dissolution of uric acid-urate stones and prophylaxis of recurrency with Magurlit. Therapia Hungarica (English edition), 1983, Volume: 31, Issue:3 Topics: Citrates; Drug Combinations; Humans; Hydrogen-Ion Concentration; Pyridoxine; Recurrence; Uric Acid;	1983
Hyperoxaluria and recurrent stone formation apparently cured by short courses of pyridoxine. British medical journal (Clinical research ed.), 1981, Jun-27, Volume: 282, Issue:6282 Topics: Adult; Female; Glycolates; Humans; Male; Oxalates; Pyridoxine; Recurrence; Urinary Calculi	1981
Effect of pyridoxine supplementation on recurrent stone formers. International journal of clinical pharmacology, therapy, and toxicology, 1982, Volume: 20, Issue:9 Topics: Adult; Alanine Transaminase; Aspartate Aminotransferases; Calcium; Humans; Oxalates; Phosphorus; Pyr	1982
Therapeutic results with Magurlit. Therapia Hungarica (English edition), 1981, Volume: 29, Issue:2 Topics: Aged; Citrates; Drug Combinations; Humans; Middle Aged; Pyridoxine; Urinary Calculi	1981
Five-year observations with Magurlit, a stone-dissolving granulate. Therapia Hungarica (English edition), 1980, Volume: 28, Issue:4 Topics: Citrates; Drug Combinations; Female; Humans; Kidney Calculi; Male; Pyridoxine; Ureteral Calculi; Uri	1980
[Progress in urolithiasis research. Report and comments on the Urolithiasis Symposium 1981, Bonn (author's transl)]. Urologia internationalis, 1981, Volume: 36, Issue:6 Topics: Allopurinol; Ascorbic Acid; Carbonates; Diet; Humans; Pyridoxine; Risk; Urinary Calculi	1981
Effect of combined supplementation of magnesium oxide and pyridoxine in calcium-oxalate stone formers. Urological research, 1994, Volume: 22, Issue:3 Topics: Adult; Calcium; Calcium Oxalate; Drug Therapy, Combination; Female; Humans; Magnesium; Magnesium Oxi	1994
Etiological and clinical patterns of urolithiasis in Turkish children. European urology, 1997, Volume: 31, Issue:4 Topics: Adolescent; Age Factors; Anti-Bacterial Agents; Bacteriuria; Benzothiadiazines; Child; Child, Presch	1997
Magnesium hydrogen carbonate natural mineral water enriched with K(+)-citrate and vitamin B6 improves urinary abnormalities in patients with calcium oxalate nephrolithiasis. Urologia internationalis, 1998, Volume: 60, Issue:2 Topics: Adult; Calcium Oxalate; Creatinine; Female; Follow-Up Studies; Humans; Hydrogen-Ion Concentration; M	1998
A comparative study of three different citrate combinations of litholytic action. International urology and nephrology, 1978, Volume: 10, Issue:3 Topics: Citrates; Drug Combinations; Humans; Hydrogen-Ion Concentration; Pyridoxine; Urinary Calculi	1978
[The care of patients with urate calculi]. Zeitschrift fur Urologie und Nephrologie, 1979, Volume: 72, Issue:5 Topics: Allopurinol; Citrates; Diet Therapy; Fluid Therapy; Humans; Hydrogen-Ion Concentration; Magnesium; P	1979
[Effect of long-term pyridoxine administration on serum and urinary values of calculi-forming substances in Ca-oxalate urolithiasis]. Vnitrni lekarstvi, 1978, Volume: 24, Issue:5 Topics: Adult; Aged; Electrolytes; Female; Humans; Long-Term Care; Male; Middle Aged; Oxalates; Pyridoxine;	1978
[Nutrition physiology and pathology. Plant fibers in nutrition (proceedings)]. Fortschritte der Medizin, 1979, Feb-08, Volume: 97, Issue:6 Topics: Aspartate Aminotransferases; Cachexia; Cholesterol; Constipation; Dietary Fiber; Energy Metabolism;	1979
Experimental oxalate urolith formation in rats. The Australian journal of experimental biology and medical science, 1979, Volume: 57, Issue:3 Topics: Animals; Ascorbic Acid; Body Weight; Calcium Oxalate; Cholecalciferol; Diet; Kidney; Male; Phosphate	1979
[The conservative therapy of urolithiasis (author's transl)]. Der Urologe. Ausg. A, 1979, Volume: 18, Issue:4 Topics: Allopurinol; Aluminum Hydroxide; Calcium; Cystine; Humans; Ion Exchange; Magnesium; Oxalates; Phosph	1979
The diurnal urinary excretion of oxalate and the effect of pyridoxine and ascorbate on oxalate excretion. European urology, 1977, Volume: 3, Issue:1 Topics: Ascorbic Acid; Circadian Rhythm; Humans; Oxalates; Pyridoxine; Urinary Calculi	1977
Magurlit, a new drug in the treatment of urinary calculus. Therapia Hungarica (English edition), 1977, Volume: 25, Issue:1 Topics: Citrates; Drug Combinations; Humans; Pyridoxine; Urinary Calculi	1977
Excretion of 4-pyridoxic acid and oxalic acid in patients with urinary calculi. Investigative urology, 1977, Volume: 15, Issue:1 Topics: Ascorbic Acid; Female; Humans; Isonicotinic Acids; Male; Oxalates; Pyridoxic Acid; Pyridoxine; Urina	1977
Primary hyperoxaluria: therapeutic strategies for the 90's. Kidney international, 1991, Volume: 40, Issue:3 Topics: Adult; Alanine Transaminase; Algorithms; Calcium Oxalate; Child; Combined Modality Therapy; Humans;	1991
Effects of oral pyridoxine upon plasma and 24-hour urinary oxalate levels in normal subjects and stone formers with idiopathic hypercalciuria. Urological research, 1990, Volume: 18, Issue:6 Topics: Calcium; Female; Humans; Hyperoxaluria; Male; Oxalates; Pyridoxine; Urinary Calculi	1990
Prophylaxis of oxalate urolithiasis with alkaline citrates. Therapia Hungarica (English edition), 1990, Volume: 38, Issue:2 Topics: Citrates; Drug Combinations; Female; Humans; Male; Oxalates; Pyridoxine; Urinary Calculi	1990
[13 cases of drug-induced calculi]. Annales d'urologie, 1988, Volume: 22, Issue:4 Topics: Aged; Aged, 80 and over; Female; Glafenine; Glyoxylates; Humans; Male; Middle Aged; Pyridoxine; Risk	1988
Formation of calcium oxalate urolithiasis in experiment and its inhibition by pyridoxine and magnesium. Czechoslovak medicine, 1986, Volume: 9, Issue:3 Topics: Animals; Calcium Oxalate; Magnesium; Male; Pyridoxine; Rats; Urinary Calculi	1986
[Recurrent calcium oxalate calculi in patients treated with piridoxylate]. Presse medicale (Paris, France : 1983), 1985, Apr-13, Volume: 14, Issue:15 Topics: Adult; Glyoxylates; Humans; Male; Middle Aged; Pyridoxine; Recurrence; Urinary Calculi	1985
Effect of magnesium and pyridoxine supplementation on glycolate induced hyperoxaluria in male albino rats. Indian journal of experimental biology, 1988, Volume: 26, Issue:7 Topics: Animals; Hyperoxaluria; Magnesium; Male; Pyridoxine; Rats; Rats, Inbred Strains; Urinary Calculi	1988
Fifteen-year experience with Magurlit in the treatment of patients with uric acid calculi. Therapia Hungarica (English edition), 1986, Volume: 34, Issue:1 Topics: Adult; Aged; Aged, 80 and over; Calcium Oxalate; Citrates; Drug Combinations; Humans; Middle Aged; P	1986
Urinary mucoprotein in pediatric urolithiasis. Journal of pediatric surgery, 1987, Volume: 22, Issue:3 Topics: Ascorbic Acid; Calculi; Child; Child, Preschool; Female; Humans; Infant; Magnesium Oxide; Male; Meth	1987
Biochemical studies on bilharzial and nonbilharzial hyperoxaluria: effect of pyridoxine and allopurinol treatment. Biochemical medicine and metabolic biology, 1987, Volume: 38, Issue:1 Topics: Adult; Alanine Transaminase; Alkaline Phosphatase; Allopurinol; Aspartate Aminotransferases; Calcium	1987
Do indomethacin, thiazide, pyridoxine or allopurinol prevent calcium oxalate stones? Contributions to nephrology, 1987, Volume: 58 Topics: Animals; Benzothiadiazines; Calcium; Calcium Oxalate; Diuretics; Gout Suppressants; Male; Pyridoxine	1987
[Calcium oxalate stones and hyperoxaluria secondary to treatment with pyridoxilate]. Annales d'urologie, 1985, Volume: 19, Issue:5 Topics: Aged; Animals; Arterial Occlusive Diseases; Calcium Oxalate; Female; Humans; Kidney Calculi; Male; M	1985
[Iatrogenic oxalic lithiasis caused by pyridoxilate]. Nephrologie, 1985, Volume: 6, Issue:5 Topics: Aged; Animals; Calcium Oxalate; Female; Humans; Iatrogenic Disease; Male; Middle Aged; Oxalates; Pyr	1985
[Drug prevention of recurring urolithiasis]. MMW, Munchener medizinische Wochenschrift, 1974, Jan-04, Volume: 116, Issue:1 Topics: Allopurinol; Aluminum; Ammonium Chloride; Ascorbic Acid; Citrates; Glycine; Humans; Magnesium; Penic	1974
Growth studies of calcium oxalate in the presence of various ions and compounds. British journal of urology, 1969, Volume: 41, Issue:2 Topics: Acrylates; Aluminum; Chelating Agents; Chemical Phenomena; Chemistry; Coloring Agents; Crystallizati	1969
Magnesium oxide-pyridoxine therapy for recurrent calcium oxalate calculi. The Journal of urology, 1974, Volume: 112, Issue:4 Topics: Calcium; Calcium Phosphates; Drug Therapy, Combination; Humans; Magnesium Oxide; Oxalates; Pyridoxin	1974
Further research on glycine content in urine in cases of oxalic urolithiasis (considering urolithiasis in seamen). Biuletyn Instytutu Medycyny Morskiej w Gdansku, 1973, Volume: 24, Issue:1 Topics: Glycine; Humans; Male; Naval Medicine; Oxalates; Pyridoxine; Urinary Calculi	1973
[Possibilities of pharmacological prevention of oxalate calculi]. Zeitschrift fur Urologie und Nephrologie, 1972, Volume: 65, Issue:11 Topics: Alginates; Allopurinol; Calcium; Diet Therapy; Diuretics; Female; Humans; Ion Exchange Resins; Magne	1972
Recurrent urinary tract calculi possibly due to inherited cystathioninuria. Aerospace medicine, 1973, Volume: 44, Issue:11 Topics: Adult; Aerospace Medicine; Chronic Disease; Cystathionine; Humans; Male; Metabolism, Inborn Errors;	1973
[Provision of pyridoxine to urolithiasis patients under treatment at Truskavets Health Resort]. Vrachebnoe delo, 1973, Volume: 12 Topics: Adult; Balneology; Chronic Disease; Diet Therapy; Female; Humans; Male; Middle Aged; Pyridoxine; Ukr	1973
Prevention of oxalate and phosphate lithiasis by alanine. Investigative urology, 1974, Volume: 12, Issue:1 Topics: Administration, Oral; Alanine; Amino Acids; Animals; Body Weight; Chromatography, Gas; Female; Glyco	1974
[A new drug (Magurlyt) in the treatment of urinary calculi]. Orvosi hetilap, 1974, Jan-27, Volume: 115, Issue:4 Topics: Administration, Oral; Citrates; Drug Combinations; Humans; Hydrogen-Ion Concentration; Pyridoxine; S	1974
[A new drug in the therapy of uric acid calculi]. Zeitschrift fur Urologie und Nephrologie, 1974, Volume: 67, Issue:2 Topics: Calcium; Citrates; Diabetes Complications; Humans; Magnesium; Pyridoxine; Sodium; Solubility; Uric A	1974
[Urolithiasis. Biochemical aspects]. Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1968, Mar-25, Volume: 88, Issue:6 Topics: Long-Term Care; Magnesium; Phosphates; Pyridoxine; Salicylamides; Urinary Calculi	1968
[Drug therapy in urinary calculi. II. Peroral litholysis and prevention]. Urologia internationalis, 1972, Volume: 27, Issue:3 Topics: Administration, Oral; Allopurinol; Cystine; Humans; Magnesium; Oxalates; Penicillamine; Phosphates;	1972
Urinary organic acids found in B6-deficient rats and calcium oxalate calculus patients. British journal of urology, 1971, Volume: 43, Issue:5 Topics: Acids; Amino Acids; Animals; Calcium; Chromatography, Paper; Citrates; Coenzyme A; Folic Acid Defici	1971
Production of urinary calculi in vitamin B6-deficient male, female and castrated male rats. The Journal of nutrition, 1970, Volume: 100, Issue:1 Topics: Animals; Body Weight; Calcium; Castration; Citrates; Female; Kidney Calculi; Liver; Magnesium; Male;	1970
[Studies on the etiology of urolithiasis: effects of vitamin B6 and vitamin B1 on urinary oxalate excretion]. Hinyokika kiyo. Acta urologica Japonica, 1969, Volume: 15, Issue:5 Topics: Adolescent; Adult; Animals; Humans; Male; Middle Aged; Oxalates; Pyridoxine; Rats; Thiamine; Urinary	1969
[Prophylactic treatment of oxalate calculi]. Zeitschrift fur Urologie und Nephrologie, 1965, Volume: 58, Issue:7 Topics: Animals; Calcium, Dietary; Cats; Humans; Magnesium Deficiency; Oxalates; Plants, Medicinal; Pyridoxi	1965
[Studies on disturbances of mineral metabolism in oxalurilithiasis and their adjustment]. Urologia internationalis, 1966, Volume: 21, Issue:4 Topics: Calcium; Citrates; Humans; Magnesium; Metabolic Diseases; Oxalates; Pyridoxine; Urinary Calculi	1966
[On the interference of certain avitaminoses in the pathogenesis of urolithiasis. Clinical and experimental study]. Acta chirurgica Italica, 1966, Volume: 22 Suppl 1 Topics: Adult; Animals; Avitaminosis; Humans; Middle Aged; Pyridoxine; Rats; Urinary Calculi; Vitamin A Defi	1966

pyridoxine and Urinary Calculi