pyridoxine has been researched along with Uremia in 25 studies
4,5-bis(hydroxymethyl)-2-methylpyridin-3-ol: structure in first source
vitamin B6 : Any member of the group of pyridines that exhibit biological activity against vitamin B6 deficiency. Vitamin B6 deficiency is associated with microcytic anemia, electroencephalographic abnormalities, dermatitis with cheilosis (scaling on the lips and cracks at the corners of the mouth) and glossitis (swollen tongue), depression and confusion, and weakened immune function. Vitamin B6 consists of the vitamers pyridoxine, pyridoxal, and pyridoxamine and their respective 5'-phosphate esters (and includes their corresponding ionized and salt forms).
Uremia: A clinical syndrome associated with the retention of renal waste products or uremic toxins in the blood. It is usually the result of RENAL INSUFFICIENCY. Most uremic toxins are end products of protein or nitrogen CATABOLISM, such as UREA or CREATININE. Severe uremia can lead to multiple organ dysfunctions with a constellation of symptoms.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Hyperhomocysteinemia is a risk factor for atherosclerosis that is common in chronic renal failure (CRF), but its cause is unknown." | 7.71 | Dimethylglycine accumulates in uremia and predicts elevated plasma homocysteine concentrations. ( Chambers, ST; Dellow, WJ; George, PM; Lever, M; McGregor, DO; Robson, RA, 2001) |
| "Hyperhomocysteinemia is a risk factor for atherosclerosis that is common in chronic renal failure (CRF), but its cause is unknown." | 3.71 | Dimethylglycine accumulates in uremia and predicts elevated plasma homocysteine concentrations. ( Chambers, ST; Dellow, WJ; George, PM; Lever, M; McGregor, DO; Robson, RA, 2001) |
| "Thus, vitamin B6 deficiency in chronically uremic rats administered with large amounts of methionine may reduce growth, lower renal function and cause abnormal metabolism of sulfur-containing amino acids." | 1.29 | Content of sulfur amino acids and vitamin B6 and related enzyme activities in rats with chronic renal failure fed a high methionine diet. ( Asagi, K; Awata, S; Kobayashi, M; Kodama, H; Nakayama, K; Nakayama, M, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 18 (72.00) | 18.7374 |
| 1990's | 5 (20.00) | 18.2507 |
| 2000's | 2 (8.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Levine, S | 1 |
| Saltzman, A | 1 |
| FATINI, G | 1 |
| SOMIGLI, M | 1 |
| MONTAGNANI, I | 1 |
| Di Paolo, N | 1 |
| De Mia, M | 1 |
| Gaggiotti, E | 1 |
| Lacour, B | 1 |
| Parry, C | 1 |
| Drüeke, T | 1 |
| Touam, M | 1 |
| Kreis, H | 1 |
| Bailly, M | 1 |
| Durand, D | 1 |
| Balcke, P | 4 |
| Schmidt, P | 3 |
| Zazgornik, J | 3 |
| Kopsa, H | 3 |
| Deutsch, E | 2 |
| Heaf, JG | 1 |
| Sorice, F | 1 |
| De Simone, C | 1 |
| Meli, D | 1 |
| Ferrari, M | 1 |
| Morellini, M | 1 |
| De Luca, D | 1 |
| Taccone Gallucci, M | 1 |
| Casciani, CU | 1 |
| Kleiner, MJ | 1 |
| Tate, SS | 1 |
| Sullivan, JF | 1 |
| Chami, J | 1 |
| Arnadottir, M | 1 |
| Brattström, L | 1 |
| Simonsen, O | 1 |
| Thysell, H | 1 |
| Hultberg, B | 1 |
| Andersson, A | 1 |
| Nilsson-Ehle, P | 1 |
| Asagi, K | 1 |
| Nakayama, M | 1 |
| Kobayashi, M | 1 |
| Awata, S | 1 |
| Nakayama, K | 1 |
| Kodama, H | 1 |
| Suliman, ME | 1 |
| Divino Filho, JC | 1 |
| Bàràny, P | 1 |
| Anderstam, B | 1 |
| Lindholm, B | 1 |
| Bergström, J | 1 |
| McGregor, DO | 1 |
| Dellow, WJ | 1 |
| Lever, M | 1 |
| George, PM | 1 |
| Robson, RA | 1 |
| Chambers, ST | 1 |
| Teehan, BP | 1 |
| Smith, LJ | 1 |
| Sigler, MH | 1 |
| Gilgore, GS | 1 |
| Schleifer, CR | 1 |
| Swendseid, ME | 1 |
| Costello, JF | 1 |
| Sadovnic, MC | 1 |
| Smith, M | 1 |
| Stolarski, C | 1 |
| Laso Guzmán, FJ | 1 |
| González-Buitrago, JM | 1 |
| Vela, R | 1 |
| Cava, F | 1 |
| de Castro, S | 1 |
| Barbari, A | 1 |
| Vaziri, ND | 1 |
| Benavides, I | 1 |
| Chen, YT | 1 |
| Said, H | 1 |
| Pahl, MV | 1 |
| Marumo, F | 1 |
| Kamata, K | 1 |
| Okubo, M | 1 |
| McVicar, M | 1 |
| Gauthier, B | 1 |
| Goodman, CT | 1 |
| Dobbelstein, H | 1 |
| Körner, WF | 1 |
| Mempel, W | 1 |
| Grosse-Wilde, H | 1 |
| Edel, HH | 1 |
| Gäng, V | 1 |
| Kult, J | 1 |
| DiPaolo, RV | 1 |
| Caviness, VS | 1 |
| Kanfer, JN | 1 |
2 trials available for pyridoxine and Uremia
| Article | Year |
|---|---|
The effect of high-dose pyridoxine and folic acid supplementation on serum lipid and plasma homocysteine concentrations in dialysis patients.
Topics: Adult; Aged; Female; Folic Acid; Glycated Hemoglobin; Homocysteine; Humans; Lipids; Lipoproteins; Ma | 1993 |
Effects of high-dose folic acid and pyridoxine on plasma and erythrocyte sulfur amino acids in hemodialysis patients.
Topics: Adult; Aged; Aged, 80 and over; Amino Acids, Sulfur; Chemotherapy, Adjuvant; Dose-Response Relations | 1999 |
23 other studies available for pyridoxine and Uremia
| Article | Year |
|---|---|
Pyridoxine (vitamin B6) toxicity: enhancement by uremia in rats.
Topics: Animals; Blood Urea Nitrogen; Creatinine; Male; Nervous System Diseases; Pyridoxine; Rats; Rats, Inb | 2002 |
[TREATMENT OF HYPERAZOTEMIA WITH A NEW PHARMACOLOGIC ASSOCIATION].
Topics: Geriatrics; Glutamates; Humans; Pyridoxine; Pyrrolidinones; Tetraethylammonium Compounds; Uremia; Ur | 1964 |
[Metadoxine in the treatment of vomiting in uremic patients under dialysis treatment].
Topics: Adolescent; Adult; Aged; Domperidone; Drug Combinations; Humans; Middle Aged; Pyridoxine; Pyrrolidin | 1984 |
Pyridoxal 5'-phosphate deficiency in uremic undialyzed, hemodialyzed, and non-uremic kidney transplant patients.
Topics: Adult; Apoenzymes; Female; Hot Temperature; Humans; Kidney Failure, Chronic; Kidney Transplantation; | 1983 |
[Intra-erythrocytic GOT activity in uremia and its behavior following pyridoxine administration].
Topics: Aspartate Aminotransferases; Combined Modality Therapy; Erythrocytes; Humans; Kidney Failure, Chroni | 1983 |
Effect of vitamin B6 administration on elevated plasma oxalic acid levels in haemodialysed patients.
Topics: Administration, Oral; Creatinine; Depression, Chemical; Humans; Injections, Intravenous; Oxalates; O | 1982 |
Liver function tests and pyridoxine levels in uremia.
Topics: Adult; Aged; Alkaline Phosphatase; Aspartate Aminotransferases; Bilirubin; Female; Humans; Liver; Li | 1982 |
Secondary hyperoxalemia in chronic renal failure.
Topics: Blood; Calcinosis; Calcium Oxalate; Creatinine; Humans; Kidney Failure, Chronic; Oxalates; Oxalic Ac | 1982 |
[Effect of vitamin B6 on some immune responses in chronic uremia (author's transl)].
Topics: Adult; Antibody Formation; Chronic Disease; Female; Humans; Immunity, Cellular; Immunocompetence; Ma | 1980 |
Vitamin B6 deficiency in maintenance dialysis patients: metabolic effects of repletion.
Topics: Adult; Amino Acids; Aspartate Aminotransferases; Blood Urea Nitrogen; Dietary Proteins; Humans; Lipo | 1980 |
Content of sulfur amino acids and vitamin B6 and related enzyme activities in rats with chronic renal failure fed a high methionine diet.
Topics: Amino Acids, Sulfur; Animals; Blood Urea Nitrogen; Body Weight; Creatinine; Cystathionine; Cystathio | 1996 |
Dimethylglycine accumulates in uremia and predicts elevated plasma homocysteine concentrations.
Topics: Adult; Aged; Aged, 80 and over; Arteriosclerosis; Betaine; Betaine-Homocysteine S-Methyltransferase; | 2001 |
Plasma pyridoxal-5'-phosphate levels and clinical correlations in chronic hemodialysis patients.
Topics: Adult; Humans; Hydralazine; Pyridoxal Phosphate; Pyridoxine; Renal Dialysis; Uremia; Vitamin B 6 Def | 1978 |
Nutritional implications of renal disease. III. Nutritional needs of patients with renal disease.
Topics: Acute Kidney Injury; Amino Acids; Animals; Calcium; Humans; Kidney Diseases; Kidney Failure, Chronic | 1977 |
Effect of vitamin B6 supplementation on plasma oxalate and oxalate removal rate in hemodialysis patients.
Topics: Alanine Transaminase; Creatinine; Humans; Hyperoxaluria; Kidney Calculi; Kidney Failure, Chronic; Ox | 1992 |
Vitamin B6 status in uremia.
Topics: Adult; Aged; Aged, 80 and over; Aspartate Aminotransferases; Creatinine; Erythrocytes; Female; Human | 1990 |
Intestinal transport of pyridoxine in experimental renal failure.
Topics: Animals; Intestinal Absorption; Jejunum; Kidney Failure, Chronic; Male; Organ Culture Techniques; Pe | 1989 |
[Oxalic acid metabolism in chronic renal failure].
Topics: Ascorbic Acid; Aspartate Aminotransferases; Combined Modality Therapy; Erythrocytes; Glycolates; Hum | 1985 |
Deranged concentrations of water-soluble vitamins in the blood of undialyzed and dialyzed patients with chronic renal failure.
Topics: Adult; Aged; Ascorbic Acid; Female; Folic Acid; Humans; Kidney Failure, Chronic; Male; Middle Aged; | 1986 |
Uremic neuropathy. Monitoring of transketolase activity inhibition in a child.
Topics: Brain; Child; Electromyography; Female; Humans; Kidney Failure, Chronic; Leg; Nervous System Disease | 1973 |
Vitamin B6 deficiency in uremia and its implications for the depression of immune responses.
Topics: Administration, Oral; Aspartate Aminotransferases; Chronic Disease; Creatinine; DNA; Erythrocytes; H | 1974 |
[Vitamin B 6 in the serum during hemodialysis and chronic uremia].
Topics: Chronic Disease; Humans; Kidney Failure, Chronic; Pyridoxine; Renal Dialysis; Uremia; Vitamin B Defi | 1974 |
Delayed maturation of the renal cortex in the vitamin B6-deficient newborn rat.
Topics: Animals; Blood Urea Nitrogen; Body Weight; Brain Chemistry; Cerebral Hemorrhage; Female; Kidney Cort | 1974 |