pyridoxine has been researched along with Trypanosomiasis, African in 2 studies
4,5-bis(hydroxymethyl)-2-methylpyridin-3-ol: structure in first source
vitamin B6 : Any member of the group of pyridines that exhibit biological activity against vitamin B6 deficiency. Vitamin B6 deficiency is associated with microcytic anemia, electroencephalographic abnormalities, dermatitis with cheilosis (scaling on the lips and cracks at the corners of the mouth) and glossitis (swollen tongue), depression and confusion, and weakened immune function. Vitamin B6 consists of the vitamers pyridoxine, pyridoxal, and pyridoxamine and their respective 5'-phosphate esters (and includes their corresponding ionized and salt forms).
Trypanosomiasis, African: A disease endemic among people and animals in Central Africa. It is caused by various species of trypanosomes, particularly T. gambiense and T. rhodesiense. Its second host is the TSETSE FLY. Involvement of the central nervous system produces African sleeping sickness. Nagana is a rapidly fatal trypanosomiasis of horses and other animals.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Both pyridoxine and pyridoxal were found to be metabolised to pyridoxal phosphate in whole cells." | 1.29 | Trypanosoma brucei brucei: uptake and metabolism of pyridoxine and pyridoxal. ( Gray, A, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Jones, DC | 1 |
| Alphey, MS | 1 |
| Wyllie, S | 1 |
| Fairlamb, AH | 1 |
| Gray, A | 1 |
2 other studies available for pyridoxine and Trypanosomiasis, African
| Article | Year |
|---|---|
Chemical, genetic and structural assessment of pyridoxal kinase as a drug target in the African trypanosome.
Topics: Amino Acid Sequence; Animals; Antiprotozoal Agents; Disease Models, Animal; Enzyme Inhibitors; Gene | 2012 |
Trypanosoma brucei brucei: uptake and metabolism of pyridoxine and pyridoxal.
Topics: Alkaline Phosphatase; Animals; Chromatography, Thin Layer; Diffusion; Male; Pyridoxal; Pyridoxine; R | 1995 |