pyridoxine has been researched along with Thrombopenia in 10 studies
4,5-bis(hydroxymethyl)-2-methylpyridin-3-ol: structure in first source
vitamin B6 : Any member of the group of pyridines that exhibit biological activity against vitamin B6 deficiency. Vitamin B6 deficiency is associated with microcytic anemia, electroencephalographic abnormalities, dermatitis with cheilosis (scaling on the lips and cracks at the corners of the mouth) and glossitis (swollen tongue), depression and confusion, and weakened immune function. Vitamin B6 consists of the vitamers pyridoxine, pyridoxal, and pyridoxamine and their respective 5'-phosphate esters (and includes their corresponding ionized and salt forms).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Complications of long-term linezolid administration include anemia and thrombocytopenia." | 5.12 | No effect of pyridoxine on the incidence of myelosuppression during prolonged linezolid treatment. ( Athanassia, S; Giamarellou, H; Giannitsioti, E; Kanellakopoulou, K; Kontopidou, F; Papadopoulos, A; Plachouras, D, 2006) |
| "Many of the adverse reactions produced by penicillamine and other compounds with an active sulfhydryl group form a distinctive pattern when viewed as a class." | 2.37 | Adverse effects profile of sulfhydryl compounds in man. ( Jaffe, IA, 1986) |
| "Two patients (5%) discontinued treatment due to thrombocytopenia." | 1.42 | Linezolid-induced haematological toxicity. ( Aquerreta, I; Leache, L; Moraza, L; Ortega, A, 2015) |
| " The aim of this study was to evaluate the influences of pyridoxine, rifampin, and renal function on hematological adverse events." | 1.34 | Comparative study of the effects of pyridoxine, rifampin, and renal function on hematological adverse events induced by linezolid. ( Bové, A; García, S; Marcos, M; Martínez, JA; Martínez, JC; Mensa, J; Ortega, M; Peñarroja, G; Soriano, A, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (70.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (20.00) | 29.6817 |
| 2010's | 1 (10.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Soriano, A | 1 |
| Ortega, M | 1 |
| García, S | 1 |
| Peñarroja, G | 1 |
| Bové, A | 1 |
| Marcos, M | 1 |
| Martínez, JC | 1 |
| Martínez, JA | 1 |
| Mensa, J | 1 |
| Moraza, L | 1 |
| Leache, L | 1 |
| Aquerreta, I | 1 |
| Ortega, A | 1 |
| MYKHAMEDZIANOVA, GS | 1 |
| GROSS, S | 1 |
| Plachouras, D | 1 |
| Giannitsioti, E | 1 |
| Athanassia, S | 1 |
| Kontopidou, F | 1 |
| Papadopoulos, A | 1 |
| Kanellakopoulou, K | 1 |
| Giamarellou, H | 1 |
| Frimpter, GW | 1 |
| Greenberg, AJ | 1 |
| Hilgartner, M | 1 |
| Fuchs, F | 1 |
| Jaffe, IA | 1 |
| Chioléro, R | 1 |
| Werner, T | 1 |
| Weinmann, HM | 1 |
| Hines, JD | 1 |
| Cowan, DH | 1 |
2 reviews available for pyridoxine and Thrombopenia
| Article | Year |
|---|---|
Adverse effects profile of sulfhydryl compounds in man.
Topics: Anemia, Aplastic; Autoimmune Diseases; Captopril; Drug Eruptions; Glomerulonephritis; Humans; Neutro | 1986 |
[10 years of penicillamine].
Topics: Cystinuria; Drug Eruptions; Gold; Hepatolenticular Degeneration; Humans; Lead Poisoning; Leukopenia; | 1966 |
2 trials available for pyridoxine and Thrombopenia
| Article | Year |
|---|---|
No effect of pyridoxine on the incidence of myelosuppression during prolonged linezolid treatment.
Topics: Acetamides; Anemia; Anti-Bacterial Agents; Female; Humans; Incidence; Linezolid; Male; Middle Aged; | 2006 |
[Rifampicin in the treatment of active pulmonary tuberculosis. Controlled trial of isoniazid-rifampicin-thiocarlide versus isoniazid-streptomycin-thiocarlide in untreated tuberculosis. Treatment of relapses with the combination rifampicin-ethambutol-thioc
Topics: Chemical and Drug Induced Liver Injury; Clinical Trials as Topic; Drug Hypersensitivity; Drug Therap | 1974 |
6 other studies available for pyridoxine and Thrombopenia
| Article | Year |
|---|---|
Comparative study of the effects of pyridoxine, rifampin, and renal function on hematological adverse events induced by linezolid.
Topics: Acetamides; Aged; Aged, 80 and over; Anemia; Anti-Infective Agents; Blood Glucose; Cohort Studies; C | 2007 |
Linezolid-induced haematological toxicity.
Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Female; Hematologic Diseases; Humans; Linezol | 2015 |
[CONGENITAL HYPOPLASTIC STATE OF THE HEMATOPOIETIC SYSTEM IN CHILDREN].
Topics: Anemia; Anemia, Aplastic; Ascorbic Acid; Bilirubin; Blood Cell Count; Blood Chemical Analysis; Blood | 1963 |
HEMATOLOGIC STUDIES ON ERYTHROPOIETIC PORPHYRIA: A NEW CASE WITH SEVERE HEMOLYSIS, CHRONIC THROMBOCYTOPENIA, AND FOLIC ACID DEFICIENCY.
Topics: Adenine Nucleotides; Anemia; Anemia, Hemolytic; Child; Drug Therapy; Erythropoiesis; Folic Acid; Fol | 1964 |
Cystathioninuria: management.
Topics: Adult; Amino Acid Metabolism, Inborn Errors; Amino Acids; Amniotic Fluid; Child; Child, Preschool; C | 1967 |
Studies on the pathogenesis of alcohol-induced sideroblastic bone-marrow abnormalities.
Topics: Adult; Alcoholism; Anemia, Sideroblastic; Bone Marrow; Bone Marrow Examination; Erythrocytes; Ethano | 1970 |