pyridoxine and Thalassemias studies

pyridoxine and Thalassemias

pyridoxine has been researched along with Thalassemias in 20 studies

4,5-bis(hydroxymethyl)-2-methylpyridin-3-ol: structure in first source
vitamin B6 : Any member of the group of pyridines that exhibit biological activity against vitamin B6 deficiency. Vitamin B6 deficiency is associated with microcytic anemia, electroencephalographic abnormalities, dermatitis with cheilosis (scaling on the lips and cracks at the corners of the mouth) and glossitis (swollen tongue), depression and confusion, and weakened immune function. Vitamin B6 consists of the vitamers pyridoxine, pyridoxal, and pyridoxamine and their respective 5'-phosphate esters (and includes their corresponding ionized and salt forms).

Research Excerpts

Excerpt	Relevance	Reference
"Treatment with pyridoxine completely corrected the anemia both in the proband and her grandson."	1.31	Familial-skewed X-chromosome inactivation as a predisposing factor for late-onset X-linked sideroblastic anemia in carrier females. ( Bergamaschi, G; Bishop, DF; Cazzola, M; Cerani, P; May, A; Rosti, V, 2000)

Research

Studies (20)

Timeframe	Studies, this research(%)	All Research%
pre-1990	18 (90.00)	18.7374
1990's	1 (5.00)	18.2507
2000's	1 (5.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Timeframe

Studies, this research(%)

All Research%

pre-1990

18 (90.00)

18.7374

1990's

1 (5.00)

18.2507

2000's

1 (5.00)

29.6817

2010's

0 (0.00)

24.3611

2020's

0 (0.00)

2.80

Authors

Authors	Studies
GEHRMANN, G	1
ORSINI, A	1
PINSARD, N	1
TRUMAN, JT	1
TALBOT, NB	1
Anderson, BB	7
Perry, GM	6
Clements, JE	2
Vullo, C	1
Cristofori, G	1
Dodd, N	1
Das, R	1
Trehan, A	1
Marwaha, N	1
Marwaha, RK	1
Cazzola, M	1
May, A	1
Bergamaschi, G	1
Cerani, P	1
Rosti, V	1
Bishop, DF	1
Modell, CB	2
Child, JA	2
Mollin, DL	3
Saary, M	1
Stephens, AD	1
Lersundi, IC	1
Horn, JE	1
Hankes, LV	1
Brown, RR	1
Schiffer, L	1
Schmaeler, M	1
Sullivan, AL	1
Weintraub, LR	1
Beutler, E	1
Paniker, NV	1
West, CJ	1
Prusek, W	1
Sladic-Simic, D	1
Martinovitch, PN	1
Zivkovic, N	1
Pavić, D	1
Martinovic, J	1
Kahn, M	1
Ranney, HM	1
Kramer, S	1
Viljoen, E	1
Becker, D	1
Zail, SS	1
Metz, J	1
Ho, R	1

Studies

GEHRMANN, G

ORSINI, A

PINSARD, N

TRUMAN, JT

TALBOT, NB

Anderson, BB

Perry, GM

Clements, JE

Vullo, C

Cristofori, G

Dodd, N

Das, R

Trehan, A

Marwaha, N

Marwaha, RK

Cazzola, M

May, A

Bergamaschi, G

Cerani, P

Rosti, V

Bishop, DF

Modell, CB

Child, JA

Mollin, DL

Saary, M

Stephens, AD

Lersundi, IC

Horn, JE

Hankes, LV

Brown, RR

Schiffer, L

Schmaeler, M

Sullivan, AL

Weintraub, LR

Beutler, E

Paniker, NV

West, CJ

Prusek, W

Sladic-Simic, D

Martinovitch, PN

Zivkovic, N

Pavić, D

Martinovic, J

Kahn, M

Ranney, HM

Kramer, S

Viljoen, E

Becker, D

Zail, SS

Metz, J

Ho, R

Reviews

2 reviews available for pyridoxine and Thalassemias

Article	Year
[VITAMIN B6 AND HEMATOPOIESIS]. Deutsche medizinische Wochenschrift (1946), 1963, Nov-15, Volume: 88 Topics: Agranulocytosis; Anemia; Anemia, Hypochromic; Hematopoiesis; Humans; Leukopenia; Pyridoxine; Thalass	1963
Sideroblastic anemias. An approach to diagnosis and management. The Medical clinics of North America, 1973, Volume: 57, Issue:2 Topics: Alcoholism; Anemia, Sideroblastic; Erythrocytes, Abnormal; Female; Folic Acid Deficiency; Genes; Hem	1973

Article

Year

[VITAMIN B6 AND HEMATOPOIESIS].

Deutsche medizinische Wochenschrift (1946), 1963, Nov-15, Volume: 88

Topics: Agranulocytosis; Anemia; Anemia, Hypochromic; Hematopoiesis; Humans; Leukopenia; Pyridoxine; Thalass

1963

Sideroblastic anemias. An approach to diagnosis and management.

The Medical clinics of North America, 1973, Volume: 57, Issue:2

Topics: Alcoholism; Anemia, Sideroblastic; Erythrocytes, Abnormal; Female; Folic Acid Deficiency; Genes; Hem

1973

Other Studies

18 other studies available for pyridoxine and Thalassemias

Article	Year
[TREATMENT OF COOLEY'S DISEASE. PRESENT ASPECTS AND FUTURE PROSPECTS]. Marseille medical, 1964, Volume: 101 Topics: Adrenocorticotropic Hormone; Blood Transfusion; Child; Corrinoids; Hematinics; Humans; Iron; Molybde	1964
ANEMIA IN CHILDHOOD. Clinical pediatrics, 1964, Volume: 3 Topics: Anemia; Anemia, Aplastic; Child; Chloramphenicol; Classification; Diagnosis, Differential; Erythrocy	1964
Red-cell metabolism of pyridoxine in controls and beta-Thalassaemia in Ferrara, Northern Italy. Biomedicine / [publiee pour l'A.A.I.C.I.G.], 1981, Volume: 35, Issue:5 Topics: Cyprus; Erythrocytes; Female; Humans; Italy; London; Malaria; Male; Pyridoxine; Thalassemia; United	1981
Low red cell activity of pyridoxine (pyridoxamine) phosphate oxidase and glutathione reductase associated with thalassaemia. Biomedicine / [publiee pour l'A.A.I.C.I.G.], 1981, Volume: 34, Issue:3 Topics: Erythrocytes; Flavin-Adenine Dinucleotide; Glutathione Reductase; Humans; Oxidoreductases Acting on	1981
The effect of riboflavin on red-cell vitamin B6 metabolism and globin synthesis. Biomedicine / [publiee pour l'A.A.I.C.I.G.], 1980, Volume: 33, Issue:2 Topics: Administration, Oral; Erythrocytes; Globins; Humans; Kinetics; Pyridoxine; Riboflavin; Thalassemia	1980
Congenital sideroblastic anemia. Indian pediatrics, 1999, Volume: 36, Issue:11 Topics: Anemia, Iron-Deficiency; Anemia, Sideroblastic; Blood Transfusion; Diagnosis, Differential; Genetic	1999
Familial-skewed X-chromosome inactivation as a predisposing factor for late-onset X-linked sideroblastic anemia in carrier females. Blood, 2000, Dec-15, Volume: 96, Issue:13 Topics: 5-Aminolevulinate Synthetase; Adolescent; Adult; Aged; Alleles; Anemia, Refractory; Anemia, Siderobl	2000
Abnormal red-cell metabolism of pyridoxine associated with beta-thalassaemia. British journal of haematology, 1979, Volume: 41, Issue:4 Topics: Adenosine Triphosphate; Adolescent; Adult; Aged; Child, Preschool; Erythrocytes; Female; Heterozygot	1979
Family studies of red-cell metabolism of pyridoxine in beta-thalassaemia. Biomedicine / [publiee pour l'A.A.I.C.I.G.], 1979, Volume: 30, Issue:1 Topics: Erythrocytes; Humans; Pedigree; Pyridoxal Phosphate; Pyridoxine; Thalassemia	1979
Effect of riboflavin on red-cell metabolism of vitamin B6. Nature, 1976, Dec-09, Volume: 264, Issue:5586 Topics: Aged; Erythrocytes; Female; Humans; Mutation; Pyridoxine; Riboflavin; Thalassemia	1976
Antimalarial effects of riboflavin deficiency. Lancet (London, England), 1986, Feb-08, Volume: 1, Issue:8476 Topics: Adolescent; Child; Erythrocytes; Humans; Malaria; Pyridoxine; Riboflavin Deficiency; Thalassemia	1986
Tryptophan metabolism in humans with various types of anemias. Blood, 1968, Volume: 32, Issue:4 Topics: Adult; Aged; Anemia; Carbon Dioxide; Carbon Isotopes; Child; Female; Humans; Kynurenine; Male; Middl	1968
Red-cell metabolism of pyridoxine in sideroblastic anaemias and related anaemias. British journal of haematology, 1972, Volume: 23 Topics: Adenosine Triphosphate; Adult; Aged; Anemia, Hypochromic; Anemia, Sideroblastic; Biological Assay; E	1972
Pyridoxine administration in sickle cell disease: an unsuccessful attempt to influence the properties of sickle hemoglobin. Biochemical medicine, 1972, Volume: 6, Issue:2 Topics: Anemia, Sickle Cell; Aspartate Aminotransferases; Blood Viscosity; Chromium Isotopes; Erythrocytes;	1972
[A 7-year observation of a cuase of Cooley's anemia]. Pediatria polska, 1972, Volume: 47, Issue:2 Topics: Blood Transfusion; Child, Preschool; Follow-Up Studies; Humans; Male; Methandrostenolone; Pyridoxine	1972
A thalassemia-like disorder in Belgrade laboratory rats. Annals of the New York Academy of Sciences, 1969, Nov-20, Volume: 165, Issue:1 Topics: Anemia; Animals; Chromium Isotopes; Electrophoresis; Erythrocytes; Erythropoiesis; Hemoglobins; Hemo	1969
The relationship between haem and globin synthesis by erythroid precursors in refractory normoblastic anaemia. Scandinavian journal of haematology, 1969, Volume: 6, Issue:5 Topics: Anemia, Hypochromic; Anemia, Pernicious; Anemia, Sideroblastic; Blood Proteins; Carbon Isotopes; Ery	1969
Disorders of iron metabolism in geriatrics. Geriatrics, 1968, Volume: 23, Issue:7 Topics: Aged; Anemia, Hypochromic; Hemochromatosis; Humans; Intestinal Absorption; Iron; Malabsorption Syndr	1968

Article

Year

[TREATMENT OF COOLEY'S DISEASE. PRESENT ASPECTS AND FUTURE PROSPECTS].

Marseille medical, 1964, Volume: 101

Topics: Adrenocorticotropic Hormone; Blood Transfusion; Child; Corrinoids; Hematinics; Humans; Iron; Molybde

1964

ANEMIA IN CHILDHOOD.

Clinical pediatrics, 1964, Volume: 3

Topics: Anemia; Anemia, Aplastic; Child; Chloramphenicol; Classification; Diagnosis, Differential; Erythrocy

1964

Red-cell metabolism of pyridoxine in controls and beta-Thalassaemia in Ferrara, Northern Italy.

Biomedicine / [publiee pour l'A.A.I.C.I.G.], 1981, Volume: 35, Issue:5

Topics: Cyprus; Erythrocytes; Female; Humans; Italy; London; Malaria; Male; Pyridoxine; Thalassemia; United

1981

Low red cell activity of pyridoxine (pyridoxamine) phosphate oxidase and glutathione reductase associated with thalassaemia.

Biomedicine / [publiee pour l'A.A.I.C.I.G.], 1981, Volume: 34, Issue:3

Topics: Erythrocytes; Flavin-Adenine Dinucleotide; Glutathione Reductase; Humans; Oxidoreductases Acting on

1981

The effect of riboflavin on red-cell vitamin B6 metabolism and globin synthesis.

Biomedicine / [publiee pour l'A.A.I.C.I.G.], 1980, Volume: 33, Issue:2

Topics: Administration, Oral; Erythrocytes; Globins; Humans; Kinetics; Pyridoxine; Riboflavin; Thalassemia

1980

Congenital sideroblastic anemia.

Indian pediatrics, 1999, Volume: 36, Issue:11

Topics: Anemia, Iron-Deficiency; Anemia, Sideroblastic; Blood Transfusion; Diagnosis, Differential; Genetic

1999

Familial-skewed X-chromosome inactivation as a predisposing factor for late-onset X-linked sideroblastic anemia in carrier females.

Blood, 2000, Dec-15, Volume: 96, Issue:13

Topics: 5-Aminolevulinate Synthetase; Adolescent; Adult; Aged; Alleles; Anemia, Refractory; Anemia, Siderobl

2000

Abnormal red-cell metabolism of pyridoxine associated with beta-thalassaemia.

British journal of haematology, 1979, Volume: 41, Issue:4

Topics: Adenosine Triphosphate; Adolescent; Adult; Aged; Child, Preschool; Erythrocytes; Female; Heterozygot

1979

Family studies of red-cell metabolism of pyridoxine in beta-thalassaemia.

Biomedicine / [publiee pour l'A.A.I.C.I.G.], 1979, Volume: 30, Issue:1

Topics: Erythrocytes; Humans; Pedigree; Pyridoxal Phosphate; Pyridoxine; Thalassemia

1979

Effect of riboflavin on red-cell metabolism of vitamin B6.

Nature, 1976, Dec-09, Volume: 264, Issue:5586

Topics: Aged; Erythrocytes; Female; Humans; Mutation; Pyridoxine; Riboflavin; Thalassemia

1976

Antimalarial effects of riboflavin deficiency.

Lancet (London, England), 1986, Feb-08, Volume: 1, Issue:8476

Topics: Adolescent; Child; Erythrocytes; Humans; Malaria; Pyridoxine; Riboflavin Deficiency; Thalassemia

1986

Tryptophan metabolism in humans with various types of anemias.

Blood, 1968, Volume: 32, Issue:4

Topics: Adult; Aged; Anemia; Carbon Dioxide; Carbon Isotopes; Child; Female; Humans; Kynurenine; Male; Middl

1968

Red-cell metabolism of pyridoxine in sideroblastic anaemias and related anaemias.

British journal of haematology, 1972, Volume: 23

Topics: Adenosine Triphosphate; Adult; Aged; Anemia, Hypochromic; Anemia, Sideroblastic; Biological Assay; E

1972

Pyridoxine administration in sickle cell disease: an unsuccessful attempt to influence the properties of sickle hemoglobin.

Biochemical medicine, 1972, Volume: 6, Issue:2

Topics: Anemia, Sickle Cell; Aspartate Aminotransferases; Blood Viscosity; Chromium Isotopes; Erythrocytes;

1972

[A 7-year observation of a cuase of Cooley's anemia].

Pediatria polska, 1972, Volume: 47, Issue:2

Topics: Blood Transfusion; Child, Preschool; Follow-Up Studies; Humans; Male; Methandrostenolone; Pyridoxine

1972

A thalassemia-like disorder in Belgrade laboratory rats.

Annals of the New York Academy of Sciences, 1969, Nov-20, Volume: 165, Issue:1

Topics: Anemia; Animals; Chromium Isotopes; Electrophoresis; Erythrocytes; Erythropoiesis; Hemoglobins; Hemo

1969

The relationship between haem and globin synthesis by erythroid precursors in refractory normoblastic anaemia.

Scandinavian journal of haematology, 1969, Volume: 6, Issue:5

Topics: Anemia, Hypochromic; Anemia, Pernicious; Anemia, Sideroblastic; Blood Proteins; Carbon Isotopes; Ery

1969

Disorders of iron metabolism in geriatrics.

Geriatrics, 1968, Volume: 23, Issue:7

Topics: Aged; Anemia, Hypochromic; Hemochromatosis; Humans; Intestinal Absorption; Iron; Malabsorption Syndr

1968