pyridoxine has been researched along with Sjogren's Syndrome in 6 studies
4,5-bis(hydroxymethyl)-2-methylpyridin-3-ol: structure in first source
vitamin B6 : Any member of the group of pyridines that exhibit biological activity against vitamin B6 deficiency. Vitamin B6 deficiency is associated with microcytic anemia, electroencephalographic abnormalities, dermatitis with cheilosis (scaling on the lips and cracks at the corners of the mouth) and glossitis (swollen tongue), depression and confusion, and weakened immune function. Vitamin B6 consists of the vitamers pyridoxine, pyridoxal, and pyridoxamine and their respective 5'-phosphate esters (and includes their corresponding ionized and salt forms).
Sjogren's Syndrome: Chronic inflammatory and autoimmune disease in which the salivary and lacrimal glands undergo progressive destruction by lymphocytes and plasma cells resulting in decreased production of saliva and tears. The primary form, often called sicca syndrome, involves both KERATOCONJUNCTIVITIS SICCA and XEROSTOMIA. The secondary form includes, in addition, the presence of a connective tissue disease, usually rheumatoid arthritis.
| Excerpt | Relevance | Reference |
|---|---|---|
| "There is evidence that pyridoxine deficiency may alter the immune response." | 6.70 | Biochemical deficiency of pyridoxine does not affect interleukin-2 production of lymphocytes from patients with Sjögren's syndrome. ( Bourges, H; Gómez, E; Kraus, A; Ortíz, V; Torres, N; Tovar, AR, 2002) |
| "There is evidence that pyridoxine deficiency may alter the immune response." | 2.70 | Biochemical deficiency of pyridoxine does not affect interleukin-2 production of lymphocytes from patients with Sjögren's syndrome. ( Bourges, H; Gómez, E; Kraus, A; Ortíz, V; Torres, N; Tovar, AR, 2002) |
| "An attempt to treat humans with Sjogren's syndrome by raising endogenous PGE1 production by administration of essential fatty acid PGE1 precursors, of pyridoxine and of vitamin C was successful in raising the rates of tear and saliva production." | 1.26 | Sjogren's syndrome and the sicca syndrome: the role of prostaglandin E1 deficiency. Treatment with essential fatty acids and vitamin C. ( Campbell, A; Horrobin, DF, 1980) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (66.67) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Katunuma, N | 1 |
| Tovar, AR | 1 |
| Gómez, E | 1 |
| Bourges, H | 1 |
| Ortíz, V | 1 |
| Kraus, A | 1 |
| Torres, N | 1 |
| Manthorpe, R | 1 |
| Hagen Petersen, S | 1 |
| Prause, JU | 1 |
| McKendry, RJ | 1 |
| Horrobin, DF | 2 |
| Campbell, A | 2 |
| McEwen, CG | 1 |
1 review available for pyridoxine and Sjogren's Syndrome
| Article | Year |
|---|---|
[Structure-based drug development and medical/biological application of cathepsin specific inhibitors].
Topics: Antigen Presentation; Autoantigens; Bone Neoplasms; Cathepsins; Dipeptides; Drug Design; Epoxy Compo | 2009 |
2 trials available for pyridoxine and Sjogren's Syndrome
| Article | Year |
|---|---|
Biochemical deficiency of pyridoxine does not affect interleukin-2 production of lymphocytes from patients with Sjögren's syndrome.
Topics: Adult; Aged; Aspartate Aminotransferases; Cross-Over Studies; Dietary Supplements; Female; Humans; I | 2002 |
Primary Sjögren's syndrome treated with Efamol/Efavit. A double-blind cross-over investigation.
Topics: Adult; Aged; Ascorbic Acid; Clinical Trials as Topic; Double-Blind Method; Drug Combinations; Fatty | 1984 |
3 other studies available for pyridoxine and Sjogren's Syndrome
| Article | Year |
|---|---|
Treatment of Sjogren's syndrome with essential fatty acids, pyridoxine and vitamin C.
Topics: Ascorbic Acid; Aspartate Aminotransferases; Aspirin; Fatty Acids, Essential; Female; Humans; Indomet | 1982 |
Treatment of the Sicca syndrome and Sjogren's syndrome with E.F.A., pyridoxine and vitamin C.
Topics: Ascorbic Acid; Fatty Acids, Essential; Humans; Lacrimal Apparatus Diseases; Pyridoxine; Salivary Gla | 1981 |
Sjogren's syndrome and the sicca syndrome: the role of prostaglandin E1 deficiency. Treatment with essential fatty acids and vitamin C.
Topics: Arthritis, Rheumatoid; Ascorbic Acid; Fatty Acids, Essential; Female; Humans; Lacrimal Apparatus Dis | 1980 |