Compounds > pyridoxine
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pyridoxine and Scleroderma, Systemic

pyridoxine has been researched along with Scleroderma, Systemic in 14 studies

4,5-bis(hydroxymethyl)-2-methylpyridin-3-ol: structure in first source
vitamin B6 : Any member of the group of pyridines that exhibit biological activity against vitamin B6 deficiency. Vitamin B6 deficiency is associated with microcytic anemia, electroencephalographic abnormalities, dermatitis with cheilosis (scaling on the lips and cracks at the corners of the mouth) and glossitis (swollen tongue), depression and confusion, and weakened immune function. Vitamin B6 consists of the vitamers pyridoxine, pyridoxal, and pyridoxamine and their respective 5'-phosphate esters (and includes their corresponding ionized and salt forms).

Scleroderma, Systemic: A chronic multi-system disorder of CONNECTIVE TISSUE. It is characterized by SCLEROSIS in the SKIN, the LUNGS, the HEART, the GASTROINTESTINAL TRACT, the KIDNEYS, and the MUSCULOSKELETAL SYSTEM. Other important features include diseased small BLOOD VESSELS and AUTOANTIBODIES. The disorder is named for its most prominent feature (hard skin), and classified into subsets by the extent of skin thickening: LIMITED SCLERODERMA and DIFFUSE SCLERODERMA.

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-199014 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
BIRK, RE3
RUPE, CE2
SHIPTON, EA1
Price, JM2
Yess, N1
Brown, RR2
Johnson, AM1
Fernandes, L1
Berry, H1
Hamilton, E1
De Antoni, A1
Muggeo, M1
Costa, C1
Allegri, G1
Crepaldi, G1
Grekin, J1
Schwartz, O1
Mehregan, A1
Mendelson, C1
Burnham, T1
Rose, DP1
Wolf, H1
Houpt, JB1
Ogryzlo, MA1
Hunt, M1
Zielke, A1
Bolland, G1
Fuleihan, FJ1
Kurban, AK1
Abboud, RT1
Beidas-Jubran, N1
Farah, FS1
Haustein, UF1
Sönnichsen, N1
Keiser, HR1
Henkin, RI1
Bartter, FC1
Sjoerdsma, A1

Other Studies

14 other studies available for pyridoxine and Scleroderma, Systemic

ArticleYear
Systemic sclerosis. Fourteen cases treated with chelation (disodium EDTA) and/or pyridoxine, with comments on the possible role of altered tryptophan metabolism in pathogenesis.
    Henry Ford Hospital medical bulletin, 1962, Volume: 10

    Topics: Basidiomycota; Chelating Agents; Edetic Acid; Humans; Pyridoxine; Scleroderma, Localized; Scleroderm

1962
HUNNER'S ULCER (CHRONIC INTERSTITIAL CYSTITIS). A MANIFESTATION OF COLLAGEN DISEASE.
    British journal of urology, 1965, Volume: 37

    Topics: Ascorbic Acid; Collagen Diseases; Corrinoids; Cystitis; Cystitis, Interstitial; Drug Therapy; Humans

1965
Tryptophan metabolism. A hitherto unreported abnormality occurring in a family.
    Archives of dermatology, 1967, Volume: 95, Issue:5

    Topics: Chlorotrianisene; Electroencephalography; Female; Humans; Injections, Intramuscular; Kynurenine; Mal

1967
Historical perspectives on penicillamine.
    Journal of the Royal College of Physicians of London, 1980, Volume: 14, Issue:2

    Topics: Animals; Chelating Agents; Chemical Phenomena; Chemistry; Hepatitis; Humans; Immunity; Lathyrism; Li

1980
Tryptophan metabolism "via" nicotimic acid in patients with scleroderma.
    Acta vitaminologica et enzymologica, 1976, Volume: 30, Issue:4-6

    Topics: Adult; Aged; Female; Humans; Kynurenine; Middle Aged; Niacinamide; Nicotinic Acids; Pyridoxine; Scle

1976
Lichen sclerosus et atrophicus and morphea.
    Archives of dermatology, 1967, Volume: 96, Issue:1

    Topics: Biopsy; Edetic Acid; Female; Humans; Lichen Planus; Middle Aged; Nicotinic Acids; Pyridoxine; Sclero

1967
Tryptophan metabolism as affected by anovulatory agents.
    Annals of the New York Academy of Sciences, 1969, Sep-30, Volume: 166, Issue:1

    Topics: Aminohippuric Acids; Chlorotrianisene; Diethylstilbestrol; Estrogens; Female; Humans; Isoniazid; Kyn

1969
Tryptophan metabolism in man (with special reference to rheumatoid arthritis and scleroderma).
    Seminars in arthritis and rheumatism, 1973, Volume: 2, Issue:4

    Topics: Arthritis, Rheumatoid; Aspirin; Cystinuria; Drug Synergism; Edetic Acid; Humans; Kynurenic Acid; Kyn

1973
The treatment of systemic sclerosis with disodium edta, pyridoxine and reserpine.
    Henry Ford Hospital medical journal, 1966, Volume: 14, Issue:2

    Topics: Adult; Aged; Edetic Acid; Female; Humans; Male; Middle Aged; Pyridoxine; Reserpine; Scleroderma, Sys

1966
[Soft tissue calcifications in collagenoses. (Contribution to the Thibierge-Weissenbach syndrome)].
    Zeitschrift fur Rheumaforschung, 1965, Volume: 24, Issue:11

    Topics: Calcinosis; Edetic Acid; Female; Hand; Humans; Infusions, Parenteral; Male; Middle Aged; Pyridoxine;

1965
Treatment of systemic sclerosis.
    Modern treatment, 1966, Volume: 3, Issue:6

    Topics: Edetic Acid; Humans; Pyridoxine; Reserpine; Scleroderma, Systemic

1966
An objective evaluation of the treatment of systemic scleroderma with disodium EDTA, pyridoxine and reserpine.
    The British journal of dermatology, 1968, Volume: 80, Issue:3

    Topics: Adult; Edetic Acid; Female; Humans; Male; Pyridoxine; Reserpine; Respiratory Function Tests; Sclerod

1968
[Clinical and physiopathological findings in lichen sclerosus et atrophicus].
    Archiv fur klinische und experimentelle Dermatologie, 1968, Volume: 231, Issue:2

    Topics: Adult; Aged; Antibodies, Antinuclear; Autoantibodies; Autonomic Nervous System; Chronaxy; Dermatomyc

1968
Loss of taste during therapy with penicillamine.
    JAMA, 1968, Feb-05, Volume: 203, Issue:6

    Topics: Adolescent; Adult; Cystinuria; Female; Food; Humans; Hydrochloric Acid; Male; Middle Aged; Penicilla

1968