pyridoxine has been researched along with Rhabdomyolysis in 3 studies
4,5-bis(hydroxymethyl)-2-methylpyridin-3-ol: structure in first source
vitamin B6 : Any member of the group of pyridines that exhibit biological activity against vitamin B6 deficiency. Vitamin B6 deficiency is associated with microcytic anemia, electroencephalographic abnormalities, dermatitis with cheilosis (scaling on the lips and cracks at the corners of the mouth) and glossitis (swollen tongue), depression and confusion, and weakened immune function. Vitamin B6 consists of the vitamers pyridoxine, pyridoxal, and pyridoxamine and their respective 5'-phosphate esters (and includes their corresponding ionized and salt forms).
Rhabdomyolysis: Necrosis or disintegration of skeletal muscle often followed by myoglobinuria.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Classic homocystinuria is due to deficiency of cystathionine beta-synthase (CBS), a pyridoxine-dependent enzyme that, depending on the molecular variants, may be co-factor responsive." | 3.96 | A cautionary tale of pyridoxine toxicity in cystathionine beta-synthase deficiency detected by two-tier newborn screening highlights the need for clear pyridoxine dosing guidelines. ( Ahmad, A; Ames, EG; Conway, RL; Moloney, SM; Pappas, KB; Scott, AJ, 2020) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (66.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Ames, EG | 1 |
| Scott, AJ | 1 |
| Pappas, KB | 1 |
| Moloney, SM | 1 |
| Conway, RL | 1 |
| Ahmad, A | 1 |
| Blowey, DL | 1 |
| Johnson, D | 1 |
| Verjee, Z | 1 |
| Shoji, Y | 2 |
| Takahashi, T | 1 |
| Sato, W | 1 |
| Takada, G | 1 |
3 other studies available for pyridoxine and Rhabdomyolysis
| Article | Year |
|---|---|
A cautionary tale of pyridoxine toxicity in cystathionine beta-synthase deficiency detected by two-tier newborn screening highlights the need for clear pyridoxine dosing guidelines.
Topics: Cystathionine beta-Synthase; Dose-Response Relationship, Drug; Female; Homocystinuria; Humans; Infan | 2020 |
Isoniazid-associated rhabdomyolysis.
Topics: Adolescent; Charcoal; Chemical and Drug Induced Liver Injury; Diazepam; Female; Humans; Isoniazid; P | 1995 |
Acute life-threatening event with rhabdomyolysis after starting on high-dose pyridoxine therapy in an infant with homocystinuria.
Topics: Acute Disease; Dose-Response Relationship, Drug; Female; Homocystinuria; Humans; Infant; Pyridoxine; | 1998 |