Page last updated: 2024-10-20

pyridoxine and Retinal Diseases

pyridoxine has been researched along with Retinal Diseases in 7 studies

4,5-bis(hydroxymethyl)-2-methylpyridin-3-ol: structure in first source
vitamin B6 : Any member of the group of pyridines that exhibit biological activity against vitamin B6 deficiency. Vitamin B6 deficiency is associated with microcytic anemia, electroencephalographic abnormalities, dermatitis with cheilosis (scaling on the lips and cracks at the corners of the mouth) and glossitis (swollen tongue), depression and confusion, and weakened immune function. Vitamin B6 consists of the vitamers pyridoxine, pyridoxal, and pyridoxamine and their respective 5'-phosphate esters (and includes their corresponding ionized and salt forms).

Retinal Diseases: Diseases involving the RETINA.

Research Excerpts

ExcerptRelevanceReference
"Four patients with gyrate atrophy on low protein (20-35 g/day), low arginine diets and one on vitamin B6 (300 mgm/day) have maintained their plasma ornithine concentrations in the range of 30-60% of pre-therapeutic trial levels for about two years."9.05A two year trial of low protein, low arginine diets or vitamin B6 for patients with gyrate atrophy. ( Berson, EL; Hanson, AH; Rosner, B; Shih, VE, 1982)
"Four patients with gyrate atrophy on low protein (20-35 g/day), low arginine diets and one on vitamin B6 (300 mgm/day) have maintained their plasma ornithine concentrations in the range of 30-60% of pre-therapeutic trial levels for about two years."5.05A two year trial of low protein, low arginine diets or vitamin B6 for patients with gyrate atrophy. ( Berson, EL; Hanson, AH; Rosner, B; Shih, VE, 1982)
"Fibroblasts from four pyridoxine responsive and three non-responsive patients with gyrate atrophy of the choroid and retina have been examined."3.67Heterogeneity and complementation analysis of fibroblasts from vitamin B6 responsive and non-responsive patients with gyrate atrophy of the choroid and retina. ( Kennaway, NG; Weleber, RG; Wirtz, MK, 1985)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19906 (85.71)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (14.29)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Punjabi, OS1
Riaz, K1
Mets, MB1
Berson, EL1
Hanson, AH1
Rosner, B1
Shih, VE1
Hayasaka, S1
Shiono, T1
Mizuno, K1
Saito, T1
Tada, K1
Matsuzawa, T1
Ishiguro, I1
Weleber, RG3
Wirtz, MK2
Kennaway, NG3
Buist, NR1
Krasnikov, PG1

Trials

1 trial available for pyridoxine and Retinal Diseases

ArticleYear
A two year trial of low protein, low arginine diets or vitamin B6 for patients with gyrate atrophy.
    Birth defects original article series, 1982, Volume: 18, Issue:6

    Topics: Adolescent; Adult; Arginine; Atrophy; Child; Choroid; Clinical Trials as Topic; Dietary Proteins; Fe

1982

Other Studies

6 other studies available for pyridoxine and Retinal Diseases

ArticleYear
Crystalline retinopathy in primary hyperoxaluria.
    Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus, 2011, Volume: 15, Issue:2

    Topics: Electroretinography; Humans; Hyperoxaluria; Hyperoxaluria, Primary; Infant; Liver Transplantation; M

2011
Hyperornithinemia, gyrate atrophy, and ornithine ketoacid transaminase.
    Advances in experimental medicine and biology, 1982, Volume: 153

    Topics: Adolescent; Adult; Atrophy; Child; Child, Preschool; Choroid; Humans; Male; Ornithine; Ornithine-Oxo

1982
Gyrate atrophy of the choroid and retina: clinical and biochemical heterogeneity and response to vitamin B6.
    Birth defects original article series, 1982, Volume: 18, Issue:6

    Topics: Adult; Aged; Atrophy; Choroid; Female; Genes, Recessive; Humans; Male; Middle Aged; Ornithine; Ornit

1982
Gyrate atrophy of the choroid and retina with hyperornithinemia: biochemical and histologic studies and response to vitamin B6.
    American journal of human genetics, 1980, Volume: 32, Issue:4

    Topics: Adult; Amino Acid Metabolism, Inborn Errors; Biopsy; Choroid; Female; Glucose Tolerance Test; Hetero

1980
[Use of antisclerotic agents in the prevention of retinal detachment in persons with cystiform dystrophy of the retina].
    Oftalmologicheskii zhurnal, 1977, Volume: 32, Issue:2

    Topics: Aged; Cysts; Humans; Immunization, Passive; Middle Aged; Propiophenones; Pyridoxine; Retinal Detachm

1977
Heterogeneity and complementation analysis of fibroblasts from vitamin B6 responsive and non-responsive patients with gyrate atrophy of the choroid and retina.
    Journal of inherited metabolic disease, 1985, Volume: 8, Issue:2

    Topics: Atrophy; Choroid; Chromosome Mapping; Fibroblasts; Genetic Complementation Test; Humans; Ornithine-O

1985