pyridoxine has been researched along with Pulmonary Embolism in 7 studies
4,5-bis(hydroxymethyl)-2-methylpyridin-3-ol: structure in first source
vitamin B6 : Any member of the group of pyridines that exhibit biological activity against vitamin B6 deficiency. Vitamin B6 deficiency is associated with microcytic anemia, electroencephalographic abnormalities, dermatitis with cheilosis (scaling on the lips and cracks at the corners of the mouth) and glossitis (swollen tongue), depression and confusion, and weakened immune function. Vitamin B6 consists of the vitamers pyridoxine, pyridoxal, and pyridoxamine and their respective 5'-phosphate esters (and includes their corresponding ionized and salt forms).
Pulmonary Embolism: Blocking of the PULMONARY ARTERY or one of its branches by an EMBOLUS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The Vitamins and Thrombosis (VITRO) study investigated the effect of homocysteine lowering by daily supplementation of B vitamins on the risk reduction of deep vein thrombosis (DVT) and pulmonary embolism (PE)." | 9.12 | Homocysteine lowering by B vitamins and the secondary prevention of deep vein thrombosis and pulmonary embolism: A randomized, placebo-controlled, double-blind trial. ( Blom, HJ; Bos, GM; Cattaneo, M; den Heijer, M; Eichinger, S; Gerrits, WB; Rosendaal, FR; Willems, HP, 2007) |
| "As lenalidomide has shown to be efficacious in both myelodysplastic syndromes and myeloproliferative neoplasms, we have treated 2 RARS-T patients, who were transfusion dependent, with lenalidomide." | 5.36 | Efficacy of single-agent lenalidomide in patients with JAK2 (V617F) mutated refractory anemia with ring sideroblasts and thrombocytosis. ( de Wolf, JT; Huls, G; Mulder, AB; Rosati, S; van de Loosdrecht, AA; Vellenga, E, 2010) |
| "The Vitamins and Thrombosis (VITRO) study investigated the effect of homocysteine lowering by daily supplementation of B vitamins on the risk reduction of deep vein thrombosis (DVT) and pulmonary embolism (PE)." | 5.12 | Homocysteine lowering by B vitamins and the secondary prevention of deep vein thrombosis and pulmonary embolism: A randomized, placebo-controlled, double-blind trial. ( Blom, HJ; Bos, GM; Cattaneo, M; den Heijer, M; Eichinger, S; Gerrits, WB; Rosendaal, FR; Willems, HP, 2007) |
| "Treatment with pyridoxine and betaine normalised her homocysteine levels and she has had no further thrombotic event since." | 1.46 | Cerebral venous thrombosis as the first presentation of classical homocystinuria in an adult patient. ( Dawson, C; Geberhiwot, T; Senthil, L; Woods, E, 2017) |
| "As lenalidomide has shown to be efficacious in both myelodysplastic syndromes and myeloproliferative neoplasms, we have treated 2 RARS-T patients, who were transfusion dependent, with lenalidomide." | 1.36 | Efficacy of single-agent lenalidomide in patients with JAK2 (V617F) mutated refractory anemia with ring sideroblasts and thrombocytosis. ( de Wolf, JT; Huls, G; Mulder, AB; Rosati, S; van de Loosdrecht, AA; Vellenga, E, 2010) |
| "We report a case of recurrent pulmonary thromboembolism in a young woman with familial hyperhomocysteinaemia." | 1.29 | Heterozygosity for homocysteinuria: a detectable and reversible risk factor for pulmonary thromboembolism. ( Aiolfi, S; Confalonieri, M; Gandola, L; Ghio, L; Mauri, F; Parigi, P; Patrini, G; Scartabellati, A, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (14.29) | 18.7374 |
| 1990's | 1 (14.29) | 18.2507 |
| 2000's | 3 (42.86) | 29.6817 |
| 2010's | 2 (28.57) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Woods, E | 1 |
| Dawson, C | 1 |
| Senthil, L | 1 |
| Geberhiwot, T | 1 |
| Huls, G | 1 |
| Mulder, AB | 1 |
| Rosati, S | 1 |
| van de Loosdrecht, AA | 1 |
| Vellenga, E | 1 |
| de Wolf, JT | 1 |
| den Heijer, M | 2 |
| Willems, HP | 2 |
| Blom, HJ | 1 |
| Gerrits, WB | 1 |
| Cattaneo, M | 1 |
| Eichinger, S | 1 |
| Rosendaal, FR | 1 |
| Bos, GM | 2 |
| Rodrigues, CA | 1 |
| Morelli, VM | 1 |
| DA Silveira, RC | 1 |
| D'Almeida, V | 1 |
| Lourenço, DM | 1 |
| Confalonieri, M | 1 |
| Parigi, P | 1 |
| Scartabellati, A | 1 |
| Aiolfi, S | 1 |
| Patrini, G | 1 |
| Ghio, L | 1 |
| Mauri, F | 1 |
| Gandola, L | 1 |
| Rosoff, CB | 1 |
| Salzman, EW | 1 |
| Gurewich, V | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Homocysteine Lowering by B Vitamins and the Secondary Prevention of Deep-Vein Thrombosis and Pulmonary Embolism. A Randomized, Placebo-Controlled, Double Blind Trial.[NCT00314990] | 620 participants | Interventional | 1996-01-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 trials available for pyridoxine and Pulmonary Embolism
| Article | Year |
|---|---|
Homocysteine lowering by B vitamins and the secondary prevention of deep vein thrombosis and pulmonary embolism: A randomized, placebo-controlled, double-blind trial.
Topics: Adolescent; Adult; Aged; Dose-Response Relationship, Drug; Double-Blind Method; Female; Folic Acid; | 2007 |
Homocysteine reduction by B-vitamin supplementation increases t-PA and PAI-1 levels in patients with venous thromboembolism.
Topics: Adolescent; Adult; Aged; Dietary Supplements; Double-Blind Method; Drug Combinations; Endothelium, V | 2007 |
Homocysteine and venous thrombosis: outline of a vitamin intervention trial.
Topics: Adult; Aged; Aged, 80 and over; Comorbidity; Double-Blind Method; Female; Folic Acid; Follow-Up Stud | 2000 |
4 other studies available for pyridoxine and Pulmonary Embolism
| Article | Year |
|---|---|
Cerebral venous thrombosis as the first presentation of classical homocystinuria in an adult patient.
Topics: Adult; Betaine; Cerebral Angiography; Computed Tomography Angiography; Diagnostic Errors; Dysarthria | 2017 |
Efficacy of single-agent lenalidomide in patients with JAK2 (V617F) mutated refractory anemia with ring sideroblasts and thrombocytosis.
Topics: Aged, 80 and over; Anabolic Agents; Anemia, Refractory; Anemia, Sideroblastic; Antineoplastic Agents | 2010 |
Heterozygosity for homocysteinuria: a detectable and reversible risk factor for pulmonary thromboembolism.
Topics: Adult; Amino Acid Metabolism, Inborn Errors; Female; Heparin; Heterozygote; Homocysteine; Humans; Pu | 1995 |
Reduction of platelet serotonin and the response to pulmonary emboli.
Topics: Animals; Blood Platelets; Cell Aggregation; Central Venous Pressure; Escherichia coli; Intestines; P | 1971 |