pyridoxine has been researched along with Primary Myelofibrosis in 3 studies
4,5-bis(hydroxymethyl)-2-methylpyridin-3-ol: structure in first source
vitamin B6 : Any member of the group of pyridines that exhibit biological activity against vitamin B6 deficiency. Vitamin B6 deficiency is associated with microcytic anemia, electroencephalographic abnormalities, dermatitis with cheilosis (scaling on the lips and cracks at the corners of the mouth) and glossitis (swollen tongue), depression and confusion, and weakened immune function. Vitamin B6 consists of the vitamers pyridoxine, pyridoxal, and pyridoxamine and their respective 5'-phosphate esters (and includes their corresponding ionized and salt forms).
Primary Myelofibrosis: A de novo myeloproliferation arising from an abnormal stem cell. It is characterized by the replacement of bone marrow by fibrous tissue, a process that is mediated by CYTOKINES arising from the abnormal clone.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Eleven of 14 patients with primary myelofibrosis were given a therapeutic trial with 250 mg of pyridoxine hydrochloride daily because of refractory anemia." | 7.66 | Response to pyridoxine hydrochloride in refractory anemia due to myelofibrosis. ( Mulder, NH; Nieweg, HO; Rojer, RA, 1978) |
| "Eleven of 14 patients with primary myelofibrosis were given a therapeutic trial with 250 mg of pyridoxine hydrochloride daily because of refractory anemia." | 3.66 | Response to pyridoxine hydrochloride in refractory anemia due to myelofibrosis. ( Mulder, NH; Nieweg, HO; Rojer, RA, 1978) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| FARRERASVALENTI, P | 1 |
| ROZMAN, C | 1 |
| WOESSNER, S | 1 |
| Rojer, RA | 1 |
| Mulder, NH | 1 |
| Nieweg, HO | 1 |
| Maas, B | 1 |
| Ruhrmann, G | 1 |
3 other studies available for pyridoxine and Primary Myelofibrosis
| Article | Year |
|---|---|
[PRENEOPLASTIC, SIDEROBLASTIC REFRACTORY ANEMIAS].
Topics: Abdominal Neoplasms; Anemia; Anemia, Refractory; Anemia, Sideroblastic; Cecal Neoplasms; Humans; Leu | 1964 |
Response to pyridoxine hydrochloride in refractory anemia due to myelofibrosis.
Topics: Anemia; Female; Hematocrit; Hemoglobins; Humans; Male; Primary Myelofibrosis; Pyridoxine | 1978 |
[Course of a case of osteomyelofibrosis which had started in infancy].
Topics: Anemia, Sideroblastic; Child; Female; Hemoglobins; Humans; Primary Myelofibrosis; Pyridoxine; Spleno | 1971 |