pyridoxine has been researched along with Pre-Eclampsia in 15 studies
4,5-bis(hydroxymethyl)-2-methylpyridin-3-ol: structure in first source
vitamin B6 : Any member of the group of pyridines that exhibit biological activity against vitamin B6 deficiency. Vitamin B6 deficiency is associated with microcytic anemia, electroencephalographic abnormalities, dermatitis with cheilosis (scaling on the lips and cracks at the corners of the mouth) and glossitis (swollen tongue), depression and confusion, and weakened immune function. Vitamin B6 consists of the vitamers pyridoxine, pyridoxal, and pyridoxamine and their respective 5'-phosphate esters (and includes their corresponding ionized and salt forms).
Pre-Eclampsia: A complication of PREGNANCY, characterized by a complex of symptoms including maternal HYPERTENSION and PROTEINURIA with or without pathological EDEMA. Symptoms may range between mild and severe. Pre-eclampsia usually occurs after the 20th week of gestation, but may develop before this time in the presence of trophoblastic disease.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Our purpose was to assess the incidence of hyperhomocysteinemia in patients with a history of preeclampsia or fetal growth restriction, to evaluate the effects of vitamin supplementation on the methionine loading test, and to study the course of subsequent pregnancies in women with hyperhomocysteinemia and a history of preeclampsia or fetal growth restriction." | 9.08 | Effects of folic acid and vitamin B6 supplementation on women with hyperhomocysteinemia and a history of preeclampsia or fetal growth restriction. ( de Vries, JI; Dekker, GA; Jakobs, C; Leeda, M; Riyazi, N; van Geijn, HP, 1998) |
| " We did not find any statistically significant differences in the risk of eclampsia (capsules: n = 1242; three trials; lozenges: n = 944; one trial), pre-eclampsia (capsules n = 1197; two trials, low quality of evidence; lozenges: n = 944; one trial, low-quality evidence) or low Apgar scores at one minute (oral pyridoxine: n = 45; one trial), between supplemented and non-supplemented groups." | 8.91 | Pyridoxine (vitamin B6) supplementation during pregnancy or labour for maternal and neonatal outcomes. ( Bhutta, ZA; Salam, RA; Zuberi, NF, 2015) |
| " The pregnancy was complicated by chronic maternal schizophrenia, severe toxaemia and maternal use of fluphenazine enanthate, dicyclomine hydrochloride, doxylamine succinate, pyridoxine hydrochloride and other drugs." | 7.66 | Multiple congenital abnormalities in a newborn boy associated with maternal use of fluphenazine enanthate and other drugs during pregnancy. ( Bury, RG; Donaldson, GL, 1982) |
| "Our purpose was to assess the incidence of hyperhomocysteinemia in patients with a history of preeclampsia or fetal growth restriction, to evaluate the effects of vitamin supplementation on the methionine loading test, and to study the course of subsequent pregnancies in women with hyperhomocysteinemia and a history of preeclampsia or fetal growth restriction." | 5.08 | Effects of folic acid and vitamin B6 supplementation on women with hyperhomocysteinemia and a history of preeclampsia or fetal growth restriction. ( de Vries, JI; Dekker, GA; Jakobs, C; Leeda, M; Riyazi, N; van Geijn, HP, 1998) |
| " We did not find any statistically significant differences in the risk of eclampsia (capsules: n = 1242; three trials; lozenges: n = 944; one trial), pre-eclampsia (capsules n = 1197; two trials, low quality of evidence; lozenges: n = 944; one trial, low-quality evidence) or low Apgar scores at one minute (oral pyridoxine: n = 45; one trial), between supplemented and non-supplemented groups." | 4.91 | Pyridoxine (vitamin B6) supplementation during pregnancy or labour for maternal and neonatal outcomes. ( Bhutta, ZA; Salam, RA; Zuberi, NF, 2015) |
| " Additionally, those with thrombophilia or hyperhomocysteinemia were treated with low molecular weight heparin and with pyridoxine and folic acid supplementation, respectively." | 3.73 | Pre-pregnant prediction of recurrent preeclampsia in normotensive thrombophilic formerly preeclamptic women receiving prophylactic antithrombotic medication. ( Aardenburg, R; de Leeuw, PW; Ekhart, TH; Peeters, LL; Spaanderman, ME; van Eyndhoven, HW, 2005) |
| " The pregnancy was complicated by chronic maternal schizophrenia, severe toxaemia and maternal use of fluphenazine enanthate, dicyclomine hydrochloride, doxylamine succinate, pyridoxine hydrochloride and other drugs." | 3.66 | Multiple congenital abnormalities in a newborn boy associated with maternal use of fluphenazine enanthate and other drugs during pregnancy. ( Bury, RG; Donaldson, GL, 1982) |
| " Restricted cubic splines were plotted to evaluate the dose-response relationship between dietary OCM-related nutrient intake and the risk of PE." | 1.72 | One-carbon metabolism-related nutrients intake is associated with lower risk of preeclampsia in pregnant women: a matched case-control study. ( Bo, Y; Cao, Y; Dou, W; Duan, D; Fu, W; Liu, Y; Lyu, Q; Ma, S; Zeng, F; Zhao, X, 2022) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 11 (73.33) | 18.7374 |
| 1990's | 1 (6.67) | 18.2507 |
| 2000's | 1 (6.67) | 29.6817 |
| 2010's | 1 (6.67) | 24.3611 |
| 2020's | 1 (6.67) | 2.80 |
| Authors | Studies |
|---|---|
| Ma, S | 1 |
| Bo, Y | 1 |
| Zhao, X | 1 |
| Cao, Y | 1 |
| Duan, D | 1 |
| Dou, W | 1 |
| Fu, W | 1 |
| Zeng, F | 1 |
| Lyu, Q | 1 |
| Liu, Y | 1 |
| Salam, RA | 1 |
| Zuberi, NF | 1 |
| Bhutta, ZA | 1 |
| Spaanderman, ME | 1 |
| Aardenburg, R | 1 |
| Ekhart, TH | 1 |
| van Eyndhoven, HW | 1 |
| de Leeuw, PW | 1 |
| Peeters, LL | 1 |
| Braunshteĭn, AE | 1 |
| Donaldson, GL | 1 |
| Bury, RG | 1 |
| Rao, VR | 1 |
| Iyengar, LR | 1 |
| Leeda, M | 1 |
| Riyazi, N | 1 |
| de Vries, JI | 1 |
| Jakobs, C | 1 |
| van Geijn, HP | 1 |
| Dekker, GA | 1 |
| Brophy, MH | 1 |
| Siiteri, PK | 1 |
| Foukas, M | 1 |
| Clarke, HC | 1 |
| Heller, S | 1 |
| Salkeld, RM | 1 |
| Körner, WF | 1 |
| Inabe, Y | 1 |
| Mizuno, K | 1 |
| Iwagaki, S | 1 |
| Klieger, JA | 2 |
| Altshuler, CH | 1 |
| Krakow, G | 1 |
| Hollister, C | 1 |
| Bortoletto, S | 1 |
| Evrard, JR | 1 |
| Pierce, R | 1 |
2 reviews available for pyridoxine and Pre-Eclampsia
| Article | Year |
|---|---|
Pyridoxine (vitamin B6) supplementation during pregnancy or labour for maternal and neonatal outcomes.
Topics: Birth Weight; Dental Caries; Dietary Supplements; Eclampsia; Female; Humans; Infant, Newborn; Labor, | 2015 |
[Clinical significance of amino acid transformations as affected by pyridoxal phosphate enzymes].
Topics: Amino Acid Metabolism, Inborn Errors; Amino Acids; Amino Acids, Essential; Animals; Arteriosclerosis | 1982 |
2 trials available for pyridoxine and Pre-Eclampsia
| Article | Year |
|---|---|
Effects of folic acid and vitamin B6 supplementation on women with hyperhomocysteinemia and a history of preeclampsia or fetal growth restriction.
Topics: Dietary Supplements; Female; Fetal Growth Retardation; Folic Acid; Follow-Up Studies; Homocysteine; | 1998 |
[Therapeutic study of Pydoxal (PAL-PO4) in pregnancy toxemia].
Topics: Clinical Trials as Topic; Female; Humans; Placebos; Pre-Eclampsia; Pregnancy; Pyridoxine | 1968 |
11 other studies available for pyridoxine and Pre-Eclampsia
| Article | Year |
|---|---|
One-carbon metabolism-related nutrients intake is associated with lower risk of preeclampsia in pregnant women: a matched case-control study.
Topics: Case-Control Studies; Choline; Eating; Female; Folic Acid; Humans; Methionine; Nutrients; Pre-Eclamp | 2022 |
Pre-pregnant prediction of recurrent preeclampsia in normotensive thrombophilic formerly preeclamptic women receiving prophylactic antithrombotic medication.
Topics: Adult; Birth Weight; Blood Pressure; Cardiac Output; Female; Fibrinolytic Agents; Folic Acid; Heart | 2005 |
Multiple congenital abnormalities in a newborn boy associated with maternal use of fluphenazine enanthate and other drugs during pregnancy.
Topics: Abnormalities, Drug-Induced; Cleft Lip; Cleft Palate; Dicyclomine; Doxylamine; Female; Fluphenazine; | 1982 |
Erythrocyte glutamate transaminase levels in normal and pre-eclamptic pregnancies.
Topics: Aspartate Aminotransferases; Erythrocytes; Female; Humans; Pre-Eclampsia; Pregnancy; Pregnancy Trime | 1981 |
Pyridoxal phosphate and hypertensive disorders of pregnancy.
Topics: Administration, Oral; Brain; Female; Fetus; Growth; Humans; Hypertension; Infant, Newborn; Injection | 1975 |
[Antagonistic interaction between human chorionic gonadotropins and pyridoxine and its significance in pregnancy toxemia].
Topics: Animals; Bufonidae; Cell Movement; Chorionic Gonadotropin; Drug Interactions; Female; Humans; Male; | 1972 |
B-vitamins in human amniotic fluid.
Topics: Amniocentesis; Amniotic Fluid; Female; Fetal Death; Folic Acid; Humans; Pre-Eclampsia; Pregnancy; Py | 1973 |
Vitamin B6 status in pregnancy.
Topics: Abortion, Spontaneous; Adolescent; Adult; Aspartate Aminotransferases; Birth Weight; Diabetes Mellit | 1973 |
Abnormal pyridoxine metabolism in toxemia of pregnancy.
Topics: Brain; Brain Chemistry; Female; Humans; Kidney; Liver; Phosphotransferases; Placenta; Pre-Eclampsia; | 1969 |
[Evaluation of a combination of antiemetics in cases of nausea and vomiting during pregnancy].
Topics: Adolescent; Adult; Antiemetics; Cyclohexanecarboxylic Acids; Female; Humans; Nausea; Pre-Eclampsia; | 1968 |
Abnormal pyridoxine metabolism in toxemia of pregnancy.
Topics: Female; Humans; Kidney; Phosphorylase Kinase; Placenta; Pre-Eclampsia; Pregnancy; Pyridoxine; Trypto | 1966 |