Page last updated: 2024-10-20

pyridoxine and Polyneuropathy, Acquired

pyridoxine has been researched along with Polyneuropathy, Acquired in 21 studies

4,5-bis(hydroxymethyl)-2-methylpyridin-3-ol: structure in first source
vitamin B6 : Any member of the group of pyridines that exhibit biological activity against vitamin B6 deficiency. Vitamin B6 deficiency is associated with microcytic anemia, electroencephalographic abnormalities, dermatitis with cheilosis (scaling on the lips and cracks at the corners of the mouth) and glossitis (swollen tongue), depression and confusion, and weakened immune function. Vitamin B6 consists of the vitamers pyridoxine, pyridoxal, and pyridoxamine and their respective 5'-phosphate esters (and includes their corresponding ionized and salt forms).

Research Excerpts

ExcerptRelevanceReference
" It is evident that guidelines established for the prevention and treatment of this problem differ between industrialised and developing countries, and that further research is needed to define the optimum dosing of pyridoxine supplementation in populations where there is a significant burden of TB and HIV."6.47Polyneuropathy, anti-tuberculosis treatment and the role of pyridoxine in the HIV/AIDS era: a systematic review. ( Benatar, M; Harrison, TB; Heckmann, JM; van der Watt, JJ, 2011)
"Pyridoxine (vitamin B6) is an essential vitamin playing a crucial role in amino acid metabolism."5.48Regressive pyridoxine-induced sensory neuronopathy in a patient with homocystinuria. ( Chanson, JB; Echaniz-Laguna, A; Mourot-Cottet, R; Noel, E, 2018)
" It is evident that guidelines established for the prevention and treatment of this problem differ between industrialised and developing countries, and that further research is needed to define the optimum dosing of pyridoxine supplementation in populations where there is a significant burden of TB and HIV."2.47Polyneuropathy, anti-tuberculosis treatment and the role of pyridoxine in the HIV/AIDS era: a systematic review. ( Benatar, M; Harrison, TB; Heckmann, JM; van der Watt, JJ, 2011)
"Pyridoxine (vitamin B6) is an essential vitamin playing a crucial role in amino acid metabolism."1.48Regressive pyridoxine-induced sensory neuronopathy in a patient with homocystinuria. ( Chanson, JB; Echaniz-Laguna, A; Mourot-Cottet, R; Noel, E, 2018)
"The exact prevalence of vitamin B6 deficiency related to neurological manifestations has not been previously reported."1.31Vitamin B6 deficiency in elderly patients on chronic peritoneal dialysis. ( Kanno, Y; Moriwaki, K; Nakamoto, H; Okada, H; Suzuki, H, 2000)
"Peripheral polyneuritis is not a disease entity but a mystery."1.23Evaluation of therapy of peripheral polyneuritis. ( IVES, ER, 1950)

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-19909 (42.86)18.7374
1990's0 (0.00)18.2507
2000's5 (23.81)29.6817
2010's6 (28.57)24.3611
2020's1 (4.76)2.80

Authors

AuthorsStudies
Stewart, SL1
Thomas, S1
Höke, E1
Simpson, D1
Singleton, JR1
Höke, A1
Echaniz-Laguna, A1
Mourot-Cottet, R1
Noel, E1
Chanson, JB1
Kulkantrakorn, K1
van der Watt, JJ2
Benatar, MG1
Harrison, TB2
Carrara, H1
Heckmann, JM2
Ngamphaiboon, N1
Sweeney, R1
Wetzler, M1
Wang, ES1
Akbayram, S1
Akgun, C1
Doğan, M1
Sayin, R1
Caksen, H1
Oner, AF2
Benatar, M1
IVES, ER1
Duman, O1
Tezcan, G1
Hazar, V1
Bay, A1
Yilmaz, C1
Yilmaz, N1
Okada, H2
Moriwaki, K2
Kanno, Y2
Sugahara, S1
Nakamoto, H2
Yoshizawa, M1
Suzuki, H2
Laaksonen, S1
Erälinna, JP1
Falck, B1
Schiffter, R1
Klinghardt, GW1
Pluvinage, R1
Korzon, M1
Charles, OW1
Roland, DA1
Edwards, HM1
Brieger, H1
Goedde, HW1
Schloot, W1
Boettcher, D1
Stoerger, R1

Reviews

2 reviews available for pyridoxine and Polyneuropathy, Acquired

ArticleYear
Polyneuropathy, anti-tuberculosis treatment and the role of pyridoxine in the HIV/AIDS era: a systematic review.
    The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease, 2011, Volume: 15, Issue:6

    Topics: Antitubercular Agents; HIV Infections; Humans; Isoniazid; Polyneuropathies; Practice Guidelines as T

2011
[Vitamin b6 and its significance in the pathology and treatment of various pathological conditions in children].
    Wiadomosci lekarskie (Warsaw, Poland : 1960), 1972, Dec-01, Volume: 25, Issue:23

    Topics: Age Factors; Anemia; Carboxy-Lyases; Child; Child, Preschool; Epilepsy; Heart Diseases; Hepatitis A;

1972

Trials

1 trial available for pyridoxine and Polyneuropathy, Acquired

ArticleYear
Vitamin B6 supplementation can improve peripheral polyneuropathy in patients with chronic renal failure on high-flux haemodialysis and human recombinant erythropoietin.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2000, Volume: 15, Issue:9

    Topics: Chronic Disease; Diabetic Neuropathies; Erythropoietin; Female; Glomerulonephritis; Humans; Kidney F

2000

Other Studies

18 other studies available for pyridoxine and Polyneuropathy, Acquired

ArticleYear
Vitamin B6 levels do not correlate with severity of neuropathy in chronic idiopathic axonal polyneuropathy.
    Journal of the peripheral nervous system : JPNS, 2022, Volume: 27, Issue:1

    Topics: Cohort Studies; Humans; Peripheral Nervous System Diseases; Polyneuropathies; Pyridoxine; Vitamin B

2022
Regressive pyridoxine-induced sensory neuronopathy in a patient with homocystinuria.
    BMJ case reports, 2018, Jun-28, Volume: 2018

    Topics: Adult; Ataxia; Dose-Response Relationship, Drug; Epilepsy; Female; Homocystinuria; Humans; Polyneuro

2018
Pyridoxine-induced sensory ataxic neuronopathy and neuropathy: revisited.
    Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2014, Volume: 35, Issue:11

    Topics: Aged, 80 and over; Ataxia; Electromyography; Humans; Male; Polyneuropathies; Pyridoxine; Vitamin B C

2014
Isoniazid exposure and pyridoxine levels in human immunodeficiency virus associated distal sensory neuropathy.
    The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease, 2015, Volume: 19, Issue:11

    Topics: Adult; Antiretroviral Therapy, Highly Active; Arylamine N-Acetyltransferase; Coinfection; Female; HI

2015
Pyridoxine treatment of vincristine-induced cranial polyneuropathy in an adult patient with acute lymphocytic leukemia: Case report and review of the literature.
    Leukemia research, 2010, Volume: 34, Issue:8

    Topics: Adult; Antineoplastic Agents, Phytogenic; Cranial Nerve Diseases; Humans; Male; Polyneuropathies; Pr

2010
Use of pyridoxine and pyridostigmine in children with vincristine-induced neuropathy.
    Indian journal of pediatrics, 2010, Volume: 77, Issue:6

    Topics: Adolescent; Antineoplastic Agents, Phytogenic; Child; Child, Preschool; Cholinesterase Inhibitors; D

2010
Evaluation of therapy of peripheral polyneuritis.
    California medicine, 1950, Volume: 73, Issue:4

    Topics: Folic Acid; Humans; Neuritis; Niacin; Polyneuropathies; Pyridoxine; Riboflavin; Thiamine; Vitamin B

1950
Treatment of vincristine-induced cranial polyneuropathy.
    Journal of pediatric hematology/oncology, 2005, Volume: 27, Issue:4

    Topics: Antineoplastic Agents, Phytogenic; Child, Preschool; Cranial Nerve Diseases; Humans; Male; Polyneuro

2005
Vincristine induced cranial polyneuropathy.
    Indian journal of pediatrics, 2006, Volume: 73, Issue:6

    Topics: Antineoplastic Agents, Phytogenic; Blepharoptosis; Child, Preschool; Cholinesterase Inhibitors; Cran

2006
Vitamin B6 deficiency in elderly patients on chronic peritoneal dialysis.
    Advances in peritoneal dialysis. Conference on Peritoneal Dialysis, 2000, Volume: 16

    Topics: Adolescent; Adult; Age Factors; Aged; Female; Humans; Male; Middle Aged; Paresthesia; Peritoneal Dia

2000
[Are vitamins dangerous?].
    Duodecim; laaketieteellinen aikakauskirja, 2001, Volume: 117, Issue:2

    Topics: Consumer Product Safety; Dietary Supplements; Female; Humans; Legislation, Food; Middle Aged; Nutrit

2001
[Bilateral horizontal gaze paralyses. Clinical analysis of three cases].
    Zeitschrift fur Neurologie, 1971, Volume: 200, Issue:4

    Topics: Abducens Nerve; Adult; Alcohol Amnestic Disorder; Ataxia; Diplopia; Female; Humans; Male; Middle Age

1971
[Relations between polyneuropathies produced by certain modern drugs, by malabsorption and by malnutrition].
    Verhandlungen der Deutschen Gesellschaft fur Pathologie, 1969, Volume: 53

    Topics: Animals; Isoniazid; Malabsorption Syndromes; Nitrofurans; Peripheral Nervous System Diseases; Polyne

1969
[Study of the therapeutic action of a combination of vitamins B1, B6 and hydroxocobalamin in large doses].
    La semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de Paris, 1968, Jan-20, Volume: 44, Issue:4

    Topics: Adult; Aged; Anemia; Brain Diseases; Epilepsy; Facial Paralysis; Fatty Liver; Female; Hemiplegia; He

1968
Thiamine deficiency identification and treatment in commercial turkeys and Coturnix quail.
    Poultry science, 1972, Volume: 51, Issue:2

    Topics: Animals; Female; Folic Acid; Injections, Subcutaneous; Male; Pantothenic Acid; Polyneuropathies; Pou

1972
Chronic carbon disulfide poisoning.
    Journal of occupational medicine. : official publication of the Industrial Medical Association, 1972, Volume: 14, Issue:2

    Topics: Arteriosclerosis; Carbon Disulfide; Chronic Disease; Coronary Disease; Europe; Humans; Monoamine Oxi

1972
[Investigations into the polymorphism of acetylation of isonicotinic acid hydrazid (INH)].
    Die Medizinische Welt, 1968, Dec-21, Volume: 51

    Topics: Asian People; Female; Genetics, Population; Humans; Isoniazid; Polymorphism, Genetic; Polyneuropathi

1968
[Clinical experiences with Neurogrisevit in neurologic diseases].
    Die Medizinische Welt, 1966, Nov-26, Volume: 48

    Topics: Facial Paralysis; Humans; Hydroxocobalamin; Polyneuropathies; Pyridoxine; Thiamine; Trigeminal Neura

1966