pyridoxine has been researched along with Polyneuropathies in 21 studies
4,5-bis(hydroxymethyl)-2-methylpyridin-3-ol: structure in first source
vitamin B6 : Any member of the group of pyridines that exhibit biological activity against vitamin B6 deficiency. Vitamin B6 deficiency is associated with microcytic anemia, electroencephalographic abnormalities, dermatitis with cheilosis (scaling on the lips and cracks at the corners of the mouth) and glossitis (swollen tongue), depression and confusion, and weakened immune function. Vitamin B6 consists of the vitamers pyridoxine, pyridoxal, and pyridoxamine and their respective 5'-phosphate esters (and includes their corresponding ionized and salt forms).
Polyneuropathies: Diseases of multiple peripheral nerves simultaneously. Polyneuropathies usually are characterized by symmetrical, bilateral distal motor and sensory impairment with a graded increase in severity distally. The pathological processes affecting peripheral nerves include degeneration of the axon, myelin or both. The various forms of polyneuropathy are categorized by the type of nerve affected (e.g., sensory, motor, or autonomic), by the distribution of nerve injury (e.g., distal vs. proximal), by nerve component primarily affected (e.g., demyelinating vs. axonal), by etiology, or by pattern of inheritance.
| Excerpt | Relevance | Reference |
|---|---|---|
| " It is evident that guidelines established for the prevention and treatment of this problem differ between industrialised and developing countries, and that further research is needed to define the optimum dosing of pyridoxine supplementation in populations where there is a significant burden of TB and HIV." | 6.47 | Polyneuropathy, anti-tuberculosis treatment and the role of pyridoxine in the HIV/AIDS era: a systematic review. ( Benatar, M; Harrison, TB; Heckmann, JM; van der Watt, JJ, 2011) |
| "Pyridoxine (vitamin B6) is an essential vitamin playing a crucial role in amino acid metabolism." | 5.48 | Regressive pyridoxine-induced sensory neuronopathy in a patient with homocystinuria. ( Chanson, JB; Echaniz-Laguna, A; Mourot-Cottet, R; Noel, E, 2018) |
| " It is evident that guidelines established for the prevention and treatment of this problem differ between industrialised and developing countries, and that further research is needed to define the optimum dosing of pyridoxine supplementation in populations where there is a significant burden of TB and HIV." | 2.47 | Polyneuropathy, anti-tuberculosis treatment and the role of pyridoxine in the HIV/AIDS era: a systematic review. ( Benatar, M; Harrison, TB; Heckmann, JM; van der Watt, JJ, 2011) |
| "Pyridoxine (vitamin B6) is an essential vitamin playing a crucial role in amino acid metabolism." | 1.48 | Regressive pyridoxine-induced sensory neuronopathy in a patient with homocystinuria. ( Chanson, JB; Echaniz-Laguna, A; Mourot-Cottet, R; Noel, E, 2018) |
| "The exact prevalence of vitamin B6 deficiency related to neurological manifestations has not been previously reported." | 1.31 | Vitamin B6 deficiency in elderly patients on chronic peritoneal dialysis. ( Kanno, Y; Moriwaki, K; Nakamoto, H; Okada, H; Suzuki, H, 2000) |
| "Peripheral polyneuritis is not a disease entity but a mystery." | 1.23 | Evaluation of therapy of peripheral polyneuritis. ( IVES, ER, 1950) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (42.86) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (23.81) | 29.6817 |
| 2010's | 6 (28.57) | 24.3611 |
| 2020's | 1 (4.76) | 2.80 |
| Authors | Studies |
|---|---|
| Stewart, SL | 1 |
| Thomas, S | 1 |
| Höke, E | 1 |
| Simpson, D | 1 |
| Singleton, JR | 1 |
| Höke, A | 1 |
| Echaniz-Laguna, A | 1 |
| Mourot-Cottet, R | 1 |
| Noel, E | 1 |
| Chanson, JB | 1 |
| Kulkantrakorn, K | 1 |
| van der Watt, JJ | 2 |
| Benatar, MG | 1 |
| Harrison, TB | 2 |
| Carrara, H | 1 |
| Heckmann, JM | 2 |
| Ngamphaiboon, N | 1 |
| Sweeney, R | 1 |
| Wetzler, M | 1 |
| Wang, ES | 1 |
| Akbayram, S | 1 |
| Akgun, C | 1 |
| Doğan, M | 1 |
| Sayin, R | 1 |
| Caksen, H | 1 |
| Oner, AF | 2 |
| Benatar, M | 1 |
| IVES, ER | 1 |
| Duman, O | 1 |
| Tezcan, G | 1 |
| Hazar, V | 1 |
| Bay, A | 1 |
| Yilmaz, C | 1 |
| Yilmaz, N | 1 |
| Okada, H | 2 |
| Moriwaki, K | 2 |
| Kanno, Y | 2 |
| Sugahara, S | 1 |
| Nakamoto, H | 2 |
| Yoshizawa, M | 1 |
| Suzuki, H | 2 |
| Laaksonen, S | 1 |
| Erälinna, JP | 1 |
| Falck, B | 1 |
| Schiffter, R | 1 |
| Klinghardt, GW | 1 |
| Pluvinage, R | 1 |
| Korzon, M | 1 |
| Charles, OW | 1 |
| Roland, DA | 1 |
| Edwards, HM | 1 |
| Brieger, H | 1 |
| Goedde, HW | 1 |
| Schloot, W | 1 |
| Boettcher, D | 1 |
| Stoerger, R | 1 |
2 reviews available for pyridoxine and Polyneuropathies
| Article | Year |
|---|---|
Polyneuropathy, anti-tuberculosis treatment and the role of pyridoxine in the HIV/AIDS era: a systematic review.
Topics: Antitubercular Agents; HIV Infections; Humans; Isoniazid; Polyneuropathies; Practice Guidelines as T | 2011 |
[Vitamin b6 and its significance in the pathology and treatment of various pathological conditions in children].
Topics: Age Factors; Anemia; Carboxy-Lyases; Child; Child, Preschool; Epilepsy; Heart Diseases; Hepatitis A; | 1972 |
1 trial available for pyridoxine and Polyneuropathies
| Article | Year |
|---|---|
Vitamin B6 supplementation can improve peripheral polyneuropathy in patients with chronic renal failure on high-flux haemodialysis and human recombinant erythropoietin.
Topics: Chronic Disease; Diabetic Neuropathies; Erythropoietin; Female; Glomerulonephritis; Humans; Kidney F | 2000 |
18 other studies available for pyridoxine and Polyneuropathies
| Article | Year |
|---|---|
Vitamin B6 levels do not correlate with severity of neuropathy in chronic idiopathic axonal polyneuropathy.
Topics: Cohort Studies; Humans; Peripheral Nervous System Diseases; Polyneuropathies; Pyridoxine; Vitamin B | 2022 |
Regressive pyridoxine-induced sensory neuronopathy in a patient with homocystinuria.
Topics: Adult; Ataxia; Dose-Response Relationship, Drug; Epilepsy; Female; Homocystinuria; Humans; Polyneuro | 2018 |
Pyridoxine-induced sensory ataxic neuronopathy and neuropathy: revisited.
Topics: Aged, 80 and over; Ataxia; Electromyography; Humans; Male; Polyneuropathies; Pyridoxine; Vitamin B C | 2014 |
Isoniazid exposure and pyridoxine levels in human immunodeficiency virus associated distal sensory neuropathy.
Topics: Adult; Antiretroviral Therapy, Highly Active; Arylamine N-Acetyltransferase; Coinfection; Female; HI | 2015 |
Pyridoxine treatment of vincristine-induced cranial polyneuropathy in an adult patient with acute lymphocytic leukemia: Case report and review of the literature.
Topics: Adult; Antineoplastic Agents, Phytogenic; Cranial Nerve Diseases; Humans; Male; Polyneuropathies; Pr | 2010 |
Use of pyridoxine and pyridostigmine in children with vincristine-induced neuropathy.
Topics: Adolescent; Antineoplastic Agents, Phytogenic; Child; Child, Preschool; Cholinesterase Inhibitors; D | 2010 |
Evaluation of therapy of peripheral polyneuritis.
Topics: Folic Acid; Humans; Neuritis; Niacin; Polyneuropathies; Pyridoxine; Riboflavin; Thiamine; Vitamin B | 1950 |
Treatment of vincristine-induced cranial polyneuropathy.
Topics: Antineoplastic Agents, Phytogenic; Child, Preschool; Cranial Nerve Diseases; Humans; Male; Polyneuro | 2005 |
Vincristine induced cranial polyneuropathy.
Topics: Antineoplastic Agents, Phytogenic; Blepharoptosis; Child, Preschool; Cholinesterase Inhibitors; Cran | 2006 |
Vitamin B6 deficiency in elderly patients on chronic peritoneal dialysis.
Topics: Adolescent; Adult; Age Factors; Aged; Female; Humans; Male; Middle Aged; Paresthesia; Peritoneal Dia | 2000 |
[Are vitamins dangerous?].
Topics: Consumer Product Safety; Dietary Supplements; Female; Humans; Legislation, Food; Middle Aged; Nutrit | 2001 |
[Bilateral horizontal gaze paralyses. Clinical analysis of three cases].
Topics: Abducens Nerve; Adult; Alcohol Amnestic Disorder; Ataxia; Diplopia; Female; Humans; Male; Middle Age | 1971 |
[Relations between polyneuropathies produced by certain modern drugs, by malabsorption and by malnutrition].
Topics: Animals; Isoniazid; Malabsorption Syndromes; Nitrofurans; Peripheral Nervous System Diseases; Polyne | 1969 |
[Study of the therapeutic action of a combination of vitamins B1, B6 and hydroxocobalamin in large doses].
Topics: Adult; Aged; Anemia; Brain Diseases; Epilepsy; Facial Paralysis; Fatty Liver; Female; Hemiplegia; He | 1968 |
Thiamine deficiency identification and treatment in commercial turkeys and Coturnix quail.
Topics: Animals; Female; Folic Acid; Injections, Subcutaneous; Male; Pantothenic Acid; Polyneuropathies; Pou | 1972 |
Chronic carbon disulfide poisoning.
Topics: Arteriosclerosis; Carbon Disulfide; Chronic Disease; Coronary Disease; Europe; Humans; Monoamine Oxi | 1972 |
[Investigations into the polymorphism of acetylation of isonicotinic acid hydrazid (INH)].
Topics: Asian People; Female; Genetics, Population; Humans; Isoniazid; Polymorphism, Genetic; Polyneuropathi | 1968 |
[Clinical experiences with Neurogrisevit in neurologic diseases].
Topics: Facial Paralysis; Humans; Hydroxocobalamin; Polyneuropathies; Pyridoxine; Thiamine; Trigeminal Neura | 1966 |