pyridoxine has been researched along with Peripheral Nerve Diseases in 85 studies
4,5-bis(hydroxymethyl)-2-methylpyridin-3-ol: structure in first source
vitamin B6 : Any member of the group of pyridines that exhibit biological activity against vitamin B6 deficiency. Vitamin B6 deficiency is associated with microcytic anemia, electroencephalographic abnormalities, dermatitis with cheilosis (scaling on the lips and cracks at the corners of the mouth) and glossitis (swollen tongue), depression and confusion, and weakened immune function. Vitamin B6 consists of the vitamers pyridoxine, pyridoxal, and pyridoxamine and their respective 5'-phosphate esters (and includes their corresponding ionized and salt forms).
| Excerpt | Relevance | Reference |
|---|---|---|
| "The role of insufficient pyridoxine as an etiologic factor in the development of carpal tunnel syndrome (CTS) has been reported and has led to the empirical use of pyridoxine to treat CTS." | 7.67 | Pyridoxine metabolism in carpal tunnel syndrome with and without peripheral neuropathy. ( Byers, CM; DeLisa, JA; Frankel, DL; Kraft, GH, 1984) |
| "It is well known that in the treatment of tuberculosis with isoniazid the complication of peripheral neuritis may arise." | 7.64 | Peripheral neuritis due to isoniazid. ( ANDREWS, RH; DEVADATTA, S; FOX, W; GANGADHARAM, PR; RAMAKRISHNAN, CV; SELKON, JB; VELU, S, 1960) |
| " Prophylactic pyridoxine supplementation during short-course chemotherapy for tuberculosis is not generally necessary in the daily 'A' regimen, but should be maintained in the twice-weekly (high-dose isoniazid) 'B' regimen for adults and children over 20 kg." | 4.77 | Acetylator phenotype and short-course chemotherapy for tuberculosis in Papua New Guinea. ( Currie, B; Hudson, B; Krause, V; Mondia, P, 1989) |
| "The role of insufficient pyridoxine as an etiologic factor in the development of carpal tunnel syndrome (CTS) has been reported and has led to the empirical use of pyridoxine to treat CTS." | 3.67 | Pyridoxine metabolism in carpal tunnel syndrome with and without peripheral neuropathy. ( Byers, CM; DeLisa, JA; Frankel, DL; Kraft, GH, 1984) |
| "It is well known that in the treatment of tuberculosis with isoniazid the complication of peripheral neuritis may arise." | 3.64 | Peripheral neuritis due to isoniazid. ( ANDREWS, RH; DEVADATTA, S; FOX, W; GANGADHARAM, PR; RAMAKRISHNAN, CV; SELKON, JB; VELU, S, 1960) |
| " In light of this, the number of reported cases of adverse health effects due to the use of vitamin B-6 have increased." | 2.72 | Vitamin B-6-Induced Neuropathy: Exploring the Mechanisms of Pyridoxine Toxicity. ( Hadtstein, F; Vrolijk, M, 2021) |
| " The form of administration (ampoules, dragées), dosage and duration of treatment were left to the individual care-providing physician." | 2.67 | [Therapy of neuropathies with a vitamin B combination. Symptomatic treatment of painful diseases of the peripheral nervous system with a combination preparation of thiamine, pyridoxine and cyanocobalamin]. ( Eckert, M; Schejbal, P, 1992) |
| "Typically, attention to peripheral neuropathies resulting from exposure to environmental agents is limited relative to more commonly diagnosed causes of peripheral neuropathy (diabetes and chemotherapeutic agents)." | 2.50 | Animal models of peripheral neuropathy due to environmental toxicants. ( Jortner, BS; Rao, DB; Sills, RC, 2014) |
| " Is pyridoxine safe for long-term use in large segments of the population, including children? The studies on children with Down's syndrome and autism, utilizing much higher doses than are used for other therapeutic purposes, seem to indicate relative safety if carefully monitored." | 2.38 | Vitamin B6 in clinical neurology. ( Bernstein, AL, 1990) |
| " An orally bioavailable GCP II inhibitor, 2-(3-mercaptopropyl) pentanedioic acid (2-MPPA), was administered daily at a dose of 30 mg/kg starting from the onset of pyridoxine injections." | 1.40 | Glutamate carboxypeptidase II inhibition behaviorally and physiologically improves pyridoxine-induced neuropathy in rats. ( Callizot, N; Potter, MC; Slusher, BS; Wozniak, KM, 2014) |
| "Pyridoxine-treated mice exhibited an increase in the hearing threshold shift and delayed latency of both ABR and AMLR in proportion to pyridoxine dosage." | 1.35 | High-dosage pyridoxine-induced auditory neuropathy and protection with coffee in mice. ( Hong, BN; Kang, TH; Kim, SY; Yi, TH, 2009) |
| "Pyridoxine may cause peripheral neuropathy and this case illustrates the need for caution in the use of this vitamin in the prevention and treatment of isoniazid induced peripheral neuropathy." | 1.28 | Exacerbation of isoniazid induced peripheral neuropathy by pyridoxine. ( Agnew, RA; Bucknall, RC; Nisar, M; Watkin, SW, 1990) |
| " We investigated the ordinary daily dosage and maximal dose of vitamin B6 widely adopted in Japan, and the amount of vitamin B6 per unit (per tablet, capsule or ampule) available in our medical practice." | 1.27 | [Peripheral sensory neuropathy produced by a megadose of vitamin B6]. ( Ishibashi, H; Matsunaga, K; Ohnishi, A; Ohtani, K; Yamamoto, T, 1985) |
| "Pyridoxine dose was 0." | 1.27 | Sensory neuropathy with low-dose pyridoxine. ( Bredesen, DE; Parry, GJ, 1985) |
| " Since the bases for this neurotoxicity are unknown, we suggest that treatment of carpal tunnel syndrome with oral pyridoxine be carefully monitored and that dosage limits not be exceeded." | 1.27 | Motor and sensory neuropathy secondary to excessive pyridoxine ingestion. ( Foca, FJ, 1985) |
| "We report peripheral paresthesias that occurred in a 39-year-old female during five years of amitriptyline administration." | 1.26 | Amitriptyline-related peripheral neuropathy relieved during pyridoxine hydrochloride administration. ( Fredericks, S; Huff, MR; Meadows, GG, 1982) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 44 (51.76) | 18.7374 |
| 1990's | 12 (14.12) | 18.2507 |
| 2000's | 11 (12.94) | 29.6817 |
| 2010's | 11 (12.94) | 24.3611 |
| 2020's | 7 (8.24) | 2.80 |
| Authors | Studies |
|---|---|
| Stewart, SL | 1 |
| Thomas, S | 1 |
| Höke, E | 1 |
| Simpson, D | 1 |
| Singleton, JR | 1 |
| Höke, A | 1 |
| Muhamad, R | 1 |
| Akrivaki, A | 1 |
| Papagiannopoulou, G | 1 |
| Zavridis, P | 1 |
| Zis, P | 1 |
| Yun, S | 1 |
| Kim, W | 1 |
| Kang, MS | 1 |
| Kim, TH | 1 |
| Kim, Y | 1 |
| Ahn, JO | 1 |
| Choi, JH | 1 |
| Hwang, IK | 1 |
| Chung, JY | 1 |
| Payne, AM | 1 |
| Sawers, A | 1 |
| Allen, JL | 1 |
| Stapley, PJ | 1 |
| Macpherson, JM | 1 |
| Ting, LH | 1 |
| Saroha, D | 1 |
| Garg, D | 1 |
| Singh, AK | 1 |
| Dhamija, RK | 1 |
| Aydin Köker, S | 1 |
| Gözmen, S | 1 |
| Demirağ, B | 1 |
| Ünalp, A | 1 |
| Karapinar, TH | 1 |
| Oymak, Y | 1 |
| Gürbüz, G | 1 |
| Öner, Eİ | 1 |
| Vergin, RC | 1 |
| Hadtstein, F | 1 |
| Vrolijk, M | 1 |
| Choudhary, CR | 1 |
| Kumari, J | 1 |
| Advani, M | 1 |
| Hasannejad, F | 1 |
| Ansar, MM | 1 |
| Rostampour, M | 1 |
| Mahdavi Fikijivar, E | 1 |
| Khakpour Taleghani, B | 1 |
| Rao, DB | 1 |
| Jortner, BS | 1 |
| Sills, RC | 1 |
| Homayouni Moghadam, F | 1 |
| Dehghan, M | 1 |
| Zarepur, E | 1 |
| Dehlavi, R | 1 |
| Ghaseminia, F | 1 |
| Ehsani, S | 1 |
| Mohammadzadeh, G | 1 |
| Barzegar, K | 1 |
| Ghavanini, AA | 1 |
| Kimpinski, K | 1 |
| Potter, MC | 1 |
| Wozniak, KM | 1 |
| Callizot, N | 2 |
| Slusher, BS | 1 |
| Berenguer-Potenciano, M | 1 |
| Villora-Morcillo, N | 1 |
| Nunez-Enamorado, N | 1 |
| Perez-Alonso, V | 1 |
| Camacho-Salas, A | 1 |
| Simon-De Las Heras, R | 1 |
| Hong, BN | 1 |
| Yi, TH | 1 |
| Kim, SY | 1 |
| Kang, TH | 1 |
| Baker, SK | 1 |
| Lipson, DM | 1 |
| Prakash, O | 1 |
| Baumann Kreuziger, LM | 1 |
| Wolanskyj, AP | 1 |
| Hanson, CA | 1 |
| Steensma, DP | 1 |
| Clement, L | 1 |
| Boylan, M | 1 |
| Miller, V | 1 |
| Driskell, J | 1 |
| Giraud, D | 1 |
| Subih, H | 1 |
| Pearson, KG | 1 |
| Misiaszek, JE | 1 |
| Hulliger, M | 1 |
| Carlson, HB | 1 |
| Anthony, EM | 1 |
| Russell, WF | 1 |
| Middlebrook, G | 1 |
| DEVADATTA, S | 2 |
| GANGADHARAM, PR | 1 |
| ANDREWS, RH | 1 |
| FOX, W | 1 |
| RAMAKRISHNAN, CV | 1 |
| SELKON, JB | 1 |
| VELU, S | 1 |
| IAROSH, AA | 1 |
| BEAUPRE, EM | 1 |
| GROWNEY, PM | 1 |
| FENNELLY, J | 1 |
| FRANK, O | 1 |
| BAKER, H | 1 |
| LEEVY, CM | 1 |
| MANDEL, W | 1 |
| FERNANDEZ, GJ | 1 |
| Shir, Y | 1 |
| Umapathi, T | 1 |
| Chaudhry, V | 1 |
| Silva, CD | 1 |
| D'Cruz, DP | 1 |
| Perry, T | 1 |
| Holloway, HW | 1 |
| Weerasuriya, A | 1 |
| Mouton, PR | 1 |
| Duffy, K | 1 |
| Mattison, JA | 1 |
| Greig, NH | 1 |
| Ozyurek, H | 1 |
| Turker, H | 1 |
| Akbalik, M | 1 |
| Bayrak, AO | 1 |
| Ince, H | 1 |
| Duru, F | 1 |
| Byers, CM | 1 |
| DeLisa, JA | 1 |
| Frankel, DL | 1 |
| Kraft, GH | 1 |
| Ferguson, RK | 1 |
| Bonjour, JP | 1 |
| Snider, DE | 1 |
| Caselli, MA | 1 |
| Prywes, HC | 1 |
| Sharnoff, DG | 1 |
| Maroni, M | 1 |
| Colombi, A | 1 |
| Gilioli, R | 1 |
| Rota, E | 1 |
| De Paschale, G | 1 |
| Castano, P | 1 |
| Foà, V | 1 |
| Duca, G | 1 |
| Meadows, GG | 1 |
| Huff, MR | 1 |
| Fredericks, S | 1 |
| Schaumburg, H | 1 |
| Kaplan, J | 1 |
| Windebank, A | 1 |
| Vick, N | 1 |
| Rasmus, S | 1 |
| Pleasure, D | 1 |
| Brown, MJ | 1 |
| Rudman, D | 1 |
| Williams, PJ | 1 |
| Crawford, D | 1 |
| Gohel, D | 1 |
| Oza, JJ | 1 |
| Panicker, MG | 1 |
| Franzblau, A | 1 |
| Rock, CL | 1 |
| Werner, RA | 1 |
| Albers, JW | 3 |
| Kelly, MP | 1 |
| Johnston, EC | 1 |
| Kretschmar, C | 1 |
| Kaumeier, S | 1 |
| Haase, W | 1 |
| Chalmers, C | 1 |
| Barker, W | 1 |
| Marks, J | 1 |
| Komiyama, A | 1 |
| James, JS | 1 |
| Warter, JM | 1 |
| Poindron, P | 1 |
| Dellon, AL | 1 |
| Dellon, ES | 1 |
| Tassler, PL | 1 |
| Ellefson, RD | 1 |
| Hendrickson, M | 1 |
| Chattopadhyay, M | 1 |
| Wolfe, D | 1 |
| Huang, S | 1 |
| Goss, J | 1 |
| Glorioso, JC | 1 |
| Mata, M | 1 |
| Fink, DJ | 1 |
| Krinke, G | 1 |
| Heid, J | 1 |
| Bittiger, H | 1 |
| Hess, R | 1 |
| Glaser, A | 1 |
| Wharton, JT | 1 |
| Rutledge, F | 1 |
| Smith, JP | 1 |
| Herson, J | 1 |
| Hodge, MP | 1 |
| Eckert, M | 1 |
| Schejbal, P | 1 |
| Mahashur, AA | 1 |
| Bernstein, AL | 1 |
| Albin, RL | 2 |
| Nisar, M | 1 |
| Watkin, SW | 1 |
| Bucknall, RC | 1 |
| Agnew, RA | 1 |
| Bassler, KH | 1 |
| Currie, B | 1 |
| Krause, V | 1 |
| Mondia, P | 1 |
| Hudson, B | 1 |
| Greenberg, HS | 1 |
| Townsend, JB | 1 |
| Lynn, RB | 1 |
| Burke, JM | 1 |
| Alessi, AG | 1 |
| Podell, RN | 1 |
| Misumi, J | 1 |
| Nagano, M | 1 |
| Kaisaku, J | 1 |
| Hitoshi, T | 1 |
| Ohnishi, A | 1 |
| Ishibashi, H | 1 |
| Ohtani, K | 1 |
| Matsunaga, K | 1 |
| Yamamoto, T | 1 |
| Parry, GJ | 1 |
| Bredesen, DE | 1 |
| Foca, FJ | 1 |
| Windebank, AJ | 1 |
| Low, PA | 1 |
| Blexrud, MD | 1 |
| Schmelzer, JD | 1 |
| Schaumburg, HH | 1 |
| Chiba, S | 1 |
| Edamura, M | 1 |
| Ito, M | 1 |
| Kikuchi, S | 1 |
| Matsumoto, H | 1 |
| Harati, Y | 1 |
| Niakan, E | 1 |
| Friedman, MA | 1 |
| Resnick, JS | 1 |
| Baer, RL | 1 |
| Waterston, JA | 1 |
| Gilligan, BS | 1 |
| Klinghardt, GW | 1 |
| Levy, L | 1 |
| Higgins, LJ | 1 |
| Burbridge, TN | 1 |
| Morris, JS | 1 |
| Ajdukiewicz, AB | 1 |
| Read, AE | 1 |
| Castelluccio, R | 1 |
| Alem, HM | 1 |
| Goldman, AL | 1 |
| Braman, SS | 1 |
| Aita, JF | 1 |
| Calame, TR | 1 |
| Cavanagh, JB | 1 |
| Krishnaswamy, K | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Long-acting Exenatide: a Tool to Stop Cognitive Decline in Dysglycemic Patients With Mild Cognitive Impairment?[NCT02847403] | Phase 3 | 40 participants (Anticipated) | Interventional | 2016-02-29 | Active, not recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
11 reviews available for pyridoxine and Peripheral Nerve Diseases
| Article | Year |
|---|---|
The Role of Vitamin B6 in Peripheral Neuropathy: A Systematic Review.
Topics: Humans; Peripheral Nervous System Diseases; Pyridoxal; Pyridoxamine; Pyridoxine; Vitamin B 6; Vitami | 2023 |
Vitamin B-6-Induced Neuropathy: Exploring the Mechanisms of Pyridoxine Toxicity.
Topics: Humans; Peripheral Nervous System Diseases; Pyridoxal Kinase; Pyridoxine; Vitamin B 6; Vitamins | 2021 |
Animal models of peripheral neuropathy due to environmental toxicants.
Topics: Acrylamide; Animals; Carbon Disulfide; Disease Models, Animal; Hazardous Substances; Hexanes; Histol | 2014 |
Revisiting the evidence for neuropathy caused by pyridoxine deficiency and excess.
Topics: Clinical Trials as Topic; Evidence-Based Medicine; Female; Humans; Male; Peripheral Nervous System D | 2014 |
Toxic neuropathy.
Topics: Animals; Boronic Acids; Bortezomib; Clinical Trials as Topic; Epothilones; Genetic Therapy; Humans; | 2005 |
Vitamins and alcoholism. III. Vitamin B6.
Topics: Alcoholism; Anemia, Sideroblastic; Animals; Aspartate Aminotransferases; False Positive Reactions; F | 1980 |
Pyridoxine supplementation during isoniazid therapy.
Topics: Humans; Isoniazid; Peripheral Nervous System Diseases; Pyridoxine; Tuberculosis; Vitamin B 6 Deficie | 1980 |
[Pyridoxine toxicity].
Topics: Diagnosis, Differential; Humans; Peripheral Nervous System Diseases; Prognosis; Pyridoxine; Sensatio | 2000 |
Vitamin B6 in clinical neurology.
Topics: Animals; Carpal Tunnel Syndrome; Chronic Disease; Depression; Headache; Humans; Movement Disorders; | 1990 |
Acetylator phenotype and short-course chemotherapy for tuberculosis in Papua New Guinea.
Topics: Acetylation; Drug Administration Schedule; Humans; Isoniazid; Papua New Guinea; Peripheral Nervous S | 1989 |
Peripheral neuropathy caused by chemical agents.
Topics: Acrylamides; Animals; Arsenic; Axons; Carbon Disulfide; Disulfiram; Humans; In Vitro Techniques; Iso | 1973 |
3 trials available for pyridoxine and Peripheral Nerve Diseases
| Article | Year |
|---|---|
[Medicamentous therapy of alcoholic polyneuropathy. Randomized double-blind study comparing 2 vitamin B preparations and a nucleotide preparation].
Topics: Adult; Alcoholism; Cytidine; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combin | 1996 |
[Therapy of neuropathies with a vitamin B combination. Symptomatic treatment of painful diseases of the peripheral nervous system with a combination preparation of thiamine, pyridoxine and cyanocobalamin].
Topics: Diabetic Neuropathies; Drug Combinations; Female; Humans; Male; Middle Aged; Neuralgia; Neurologic E | 1992 |
Isoniazid-induced vitamin B6 deficiency. Metabolic studies and preliminary vitamin B6 excretion studies.
Topics: Aspartate Aminotransferases; Blood Urea Nitrogen; Erythrocytes; Humans; Isoniazid; Leukocyte Count; | 1967 |
71 other studies available for pyridoxine and Peripheral Nerve Diseases
| Article | Year |
|---|---|
Vitamin B6 levels do not correlate with severity of neuropathy in chronic idiopathic axonal polyneuropathy.
Topics: Cohort Studies; Humans; Peripheral Nervous System Diseases; Polyneuropathies; Pyridoxine; Vitamin B | 2022 |
Neuropathological changes in dorsal root ganglia induced by pyridoxine in dogs.
Topics: Animals; Disease Models, Animal; Dogs; Ganglia, Spinal; H-Reflex; Neuroglia; Neurons; Peripheral Ner | 2020 |
Reorganization of motor modules for standing reactive balance recovery following pyridoxine-induced large-fiber peripheral sensory neuropathy in cats.
Topics: Animals; Cats; Disease Models, Animal; Electromyography; Muscle, Skeletal; Nerve Fibers, Myelinated; | 2020 |
Irreversible neuropathy in extremely-drug resistant tuberculosis: An unfortunate clinical conundrum.
Topics: Adult; Aminosalicylic Acid; Antitubercular Agents; Clofazimine; Cycloserine; Deprescriptions; Diaryl | 2020 |
Effect of pyridoxine plus pyridostigmine treatment on vincristine-induced peripheral neuropathy in pediatric patients with acute lymphoblastic leukemia: a single-center experience.
Topics: Antineoplastic Agents, Phytogenic; Child; Child, Preschool; Humans; Infant; Peripheral Nervous Syste | 2021 |
Isoniazid induced early-onset of motor dominant neuropathy and treatment with high dose of pyridoxine.
Topics: Adult; Antitubercular Agents; Diagnosis, Differential; Female; Humans; Isoniazid; Peripheral Nervous | 2018 |
Improvement of pyridoxine-induced peripheral neuropathy by Cichorium intybus hydroalcoholic extract through GABAergic system.
Topics: Animals; Cichorium intybus; GABAergic Neurons; Glutamic Acid; Male; Peripheral Nervous System Diseas | 2019 |
Oleo gum resin of Ferula assa-foetida L. ameliorates peripheral neuropathy in mice.
Topics: Action Potentials; Animals; Ferula; In Vitro Techniques; Male; Mice, Inbred BALB C; Neuroprotective | 2014 |
Glutamate carboxypeptidase II inhibition behaviorally and physiologically improves pyridoxine-induced neuropathy in rats.
Topics: Animals; Behavior, Animal; Female; Glutamate Carboxypeptidase II; Glutarates; Motor Activity; Neurod | 2014 |
[Therapeutic response to pyridoxine and pyridostigmine in a paediatric case of severe peripheral and cranial polyneuropathy due to vincristine].
Topics: Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Blepharoptosis; Cranial Nerve Diseases | 2015 |
High-dosage pyridoxine-induced auditory neuropathy and protection with coffee in mice.
Topics: Alkaloids; Animals; Auditory Pathways; Caffeine; Cochlea; Cochlear Nerve; Coffee; Evoked Potentials, | 2009 |
Vincristine-induced peripheral neuropathy in a neonate with congenital acute lymphoblastic leukemia.
Topics: Acetylcysteine; Antineoplastic Agents, Phytogenic; Carnitine; Drug Therapy, Combination; Free Radica | 2010 |
Dose of pyridoxine in TB regimens.
Topics: Antitubercular Agents; Dose-Response Relationship, Drug; Humans; Peripheral Nervous System Diseases; | 2010 |
Lack of efficacy of pyridoxine (vitamin B6) treatment in acquired idiopathic sideroblastic anaemia, including refractory anaemia with ring sideroblasts.
Topics: 5-Aminolevulinate Synthetase; Adult; Aged; Aged, 80 and over; Anemia, Refractory; Anemia, Sideroblas | 2011 |
Vitamin B-6 vitamer levels in plasma and related symptoms in hemodialysis subjects taking low- and high-dose renal multivitamin supplements.
Topics: Dietary Supplements; Dose-Response Relationship, Drug; Humans; Peripheral Nervous System Diseases; P | 2012 |
Chemical ablation of sensory afferents in the walking system of the cat abolishes the capacity for functional recovery after peripheral nerve lesions.
Topics: Afferent Pathways; Animals; Cats; Electromyography; Gait; Muscle Denervation; Muscle Spindles; Muscl | 2003 |
Prophylaxis of isoniazid neuropathy with pyridoxine.
Topics: Humans; Isomerism; Isoniazid; Nervous System Diseases; Niacin; Nicotinic Acids; Peripheral Nervous S | 1956 |
Peripheral neuritis due to isoniazid.
Topics: Africa, Eastern; Folic Acid; Humans; India; Isoniazid; Neuritis; Peripheral Nervous System Diseases; | 1960 |
[The use of vitamin B-6 in some diseases of the peripheral nervous system].
Topics: Humans; Peripheral Nervous System; Peripheral Nervous System Diseases; Pyridoxine; Vitamin B 6; Vita | 1963 |
PYRIDOXINE-RESPONSIVE ANEMIA WITH NEUROPATHY.
Topics: Anemia; Anemia, Sideroblastic; Black People; Genetic Diseases, X-Linked; Humans; Peripheral Nervous | 1963 |
PERIPHERAL NEUROPATHY OF THE ALCOHOLIC: I, AETIOLOGICAL ROLE OF ANEURIN AND OTHER B-COMPLEX VITAMINS.
Topics: Alcoholism; Biotin; Blood Chemical Analysis; Corrinoids; Folic Acid; Hematinics; Humans; Niacin; Nic | 1964 |
ISONIAZID-INDUCED ENCEPHALOPATHY.
Topics: Brain Diseases; Drug Therapy; Epilepsy; Epilepsy, Tonic-Clonic; Isoniazid; Peripheral Nervous System | 1965 |
Pyridoxine and the isoniazid-induced neuropathy.
Topics: Humans; Isoniazid; Peripheral Nervous System Diseases; Pyridoxine; Vitamin B 6 | 1959 |
[Pyridoxine hydrochloride (vitamin B6) in therapy; study of its action in peripheral nerve diseases].
Topics: Humans; Peripheral Nervous System Diseases; Pyridoxine; Vitamin B 6 | 1951 |
Comment on Wang et al.: Thiamine, pyridoxine, cyanocobalamin and their combination inhibit thermal, but not mechanical hyperalgesia in rats with primary sensory neuron injury (Pain 2005;114:266-77).
Topics: Animals; Drug Therapy, Combination; Hyperalgesia; Peripheral Nervous System Diseases; Pyridoxine; Ra | 2005 |
Pyridoxine toxicity courtesy of your local health food store.
Topics: Diagnosis, Differential; Dietary Supplements; Female; Food, Organic; Humans; Lupus Erythematosus, Sy | 2006 |
Evidence of GLP-1-mediated neuroprotection in an animal model of pyridoxine-induced peripheral sensory neuropathy.
Topics: Amino Acid Sequence; Animals; Behavior, Animal; Blood Glucose; Body Weight; Exenatide; Ganglia, Spin | 2007 |
Pyridoxine and pyridostigmine treatment in vincristine-induced neuropathy.
Topics: Antineoplastic Combined Chemotherapy Protocols; Axonal Transport; Blepharoptosis; Child, Preschool; | 2007 |
Pyridoxine metabolism in carpal tunnel syndrome with and without peripheral neuropathy.
Topics: Aspartate Aminotransferases; Carpal Tunnel Syndrome; Electromyography; Erythrocytes; Female; Humans; | 1984 |
Where did you get those shoes ?
Topics: Aged; Diagnosis, Differential; Humans; Male; Peripheral Nervous System Diseases; Pyridoxine; Shoes | 1984 |
Isoniazid toxicity as a cause of peripheral neuropathy. Case presentation and discussion.
Topics: Female; Foot Diseases; Humans; Isoniazid; Middle Aged; Peripheral Nervous System Diseases; Pyridoxin | 1981 |
Effects of ganglioside therapy on experimental CS2 neuropathy.
Topics: Animals; Carbon Disulfide; Drug Therapy, Combination; Electromyography; Gangliosides; Male; Nerve Re | 1981 |
Amitriptyline-related peripheral neuropathy relieved during pyridoxine hydrochloride administration.
Topics: Adult; Amitriptyline; Humans; Lithium; Male; Paresthesia; Peripheral Nervous System Diseases; Pyrido | 1982 |
Sensory neuropathy from pyridoxine abuse. A new megavitamin syndrome.
Topics: Adult; Edema; Gait; Humans; Male; Orthomolecular Therapy; Peripheral Nervous System Diseases; Pyrido | 1983 |
Megadose vitamins. Use and misuse.
Topics: Humans; Metabolism, Inborn Errors; Nutritional Requirements; Orthomolecular Therapy; Peripheral Nerv | 1983 |
Sensory neuropathy from pyridoxine abuse.
Topics: Aged; Humans; Peripheral Nervous System Diseases; Pyridoxine; Substance-Related Disorders | 1984 |
Excessive use of pyridoxine.
Topics: Humans; Peripheral Nervous System Diseases; Pyridoxine | 1984 |
Sensory neuropathy from megadoses of pyridoxine.
Topics: Adult; Ataxia; Female; Humans; Orthomolecular Therapy; Peripheral Nervous System Diseases; Pyridoxin | 1984 |
Vitamin B6 toxicity: a new megavitamin syndrome.
Topics: Adult; Ataxia; Female; Humans; Male; Orthomolecular Therapy; Peripheral Nervous System Diseases; Pyr | 1984 |
Pyridoxine and isonex.
Topics: Humans; Isoniazid; Peripheral Nervous System Diseases; Pyridoxine | 1993 |
The relationship of vitamin B6 status to median nerve function and carpal tunnel syndrome among active industrial workers.
Topics: Adult; Automobiles; Carpal Tunnel Syndrome; Electrophysiology; Female; Humans; Male; Median Nerve; M | 1996 |
Evidence on vitamin B6 questioned.
Topics: Case-Control Studies; Female; Humans; Peripheral Nervous System Diseases; Pyridoxine; Research Desig | 1998 |
Evidence on vitamin B6 questioned.
Topics: Female; Humans; Peripheral Nervous System Diseases; Pyridoxine | 1998 |
Neuropathy: nutritional prevention/treatment suggested.
Topics: Anti-HIV Agents; Calcium; HIV Infections; Humans; Magnesium; Peripheral Nervous System Diseases; Pyr | 1999 |
Pyridoxine-induced neuropathy in rats: a sensory neuropathy that responds to 4-methylcatechol.
Topics: Animals; Body Weight; Catechols; Disease Models, Animal; Electromyography; Female; Neurons, Afferent | 2001 |
Experimental model of pyridoxine (B6) deficiency-induced neuropathy.
Topics: Animals; Axons; Disease Models, Animal; Female; Gait; Nerve Fibers, Myelinated; Peripheral Nervous S | 2001 |
In vivo gene therapy for pyridoxine-induced neuropathy by herpes simplex virus-mediated gene transfer of neurotrophin-3.
Topics: Animals; Behavior, Animal; Cells, Cultured; Disease Models, Animal; Electrophysiology; Ganglia, Spin | 2002 |
Sensory denervation of the plantar lumbrical muscle spindles in pyridoxine neuropathy.
Topics: Animals; Male; Microscopy, Electron; Muscle Spindles; Peripheral Nervous System Diseases; Pyridoxine | 1978 |
[Peripheral neurologic diseases. Treatment using medivitan].
Topics: Drug Combinations; Humans; Peripheral Nervous System Diseases; Pyridoxine; Vitamin B 12 | 1978 |
Hexamethylmelamine: an evaluation of its role in the treatment of ovarian cancer.
Topics: Adult; Altretamine; Female; Hematologic Diseases; Humans; Ovarian Neoplasms; Peripheral Nervous Syst | 1979 |
Isoniazid induced peripheral neuropathy.
Topics: Humans; Isoniazid; Peripheral Nervous System Diseases; Pyridoxine; Sensation Disorders | 1992 |
Long-term follow-up of pyridoxine-induced acute sensory neuropathy-neuronopathy.
Topics: Action Potentials; Adult; Electrophysiology; Female; Follow-Up Studies; Humans; Median Nerve; Muscle | 1990 |
Exacerbation of isoniazid induced peripheral neuropathy by pyridoxine.
Topics: Acetylation; Arthritis, Rheumatoid; Ethambutol; Humans; Isoniazid; Male; Middle Aged; Mycobacterium | 1990 |
[Uses and dangers of Vitamin B6 megavitamin therapy].
Topics: Humans; Orthomolecular Therapy; Peripheral Nervous System Diseases; Pyridoxine | 1990 |
Acute sensory neuropathy-neuronopathy from pyridoxine overdose.
Topics: Acute Disease; Adult; Female; Humans; Male; Mushroom Poisoning; Peripheral Nervous System Diseases; | 1987 |
Nutritional supplementation with megadoses of vitamin B6. Effective therapy, placebo, or potentiator of neuropathy?
Topics: Adult; Female; Humans; Male; Nutritional Physiological Phenomena; Orthomolecular Therapy; Peripheral | 1985 |
Effects of vitamin B12 and B6 on 2,5-hexanedione-induced neuropathy.
Topics: Animals; Hexanones; Ketones; Male; Peripheral Nervous System Diseases; Pyridoxine; Rats; Rats, Inbre | 1985 |
[Peripheral sensory neuropathy produced by a megadose of vitamin B6].
Topics: Animals; Europe; Humans; Japan; Male; Neurons, Afferent; Peripheral Nerves; Peripheral Nervous Syste | 1985 |
Sensory neuropathy with low-dose pyridoxine.
Topics: Adult; Female; Humans; Male; Middle Aged; Peripheral Nervous System Diseases; Pyridoxine; Sensation; | 1985 |
Motor and sensory neuropathy secondary to excessive pyridoxine ingestion.
Topics: Aged; Carpal Tunnel Syndrome; Female; Humans; Leg; Motor Neurons; Neural Conduction; Neurons, Affere | 1985 |
Pyridoxine neuropathy in rats: specific degeneration of sensory axons.
Topics: Animals; Axons; Male; Neural Conduction; Oxygen Consumption; Peripheral Nervous System Diseases; Pyr | 1985 |
[Experimental pyridoxine neuropathy--an electrophysiological and histological study in rabbits].
Topics: Animals; Disease Models, Animal; Male; Peripheral Nervous System Diseases; Pyridoxine; Rabbits | 1985 |
Hydrazine toxicity, pyridoxine therapy, and peripheral neuropathy.
Topics: Adult; Humans; Hydrazines; Male; Peripheral Nervous System Diseases; Pyridoxine | 1986 |
Subepidermal vesicular dermatosis and sensory peripheral neuropathy caused by pyridoxine abuse.
Topics: Female; Humans; Menstruation; Middle Aged; Peripheral Nervous System Diseases; Pyridoxine; Self Medi | 1986 |
Pyridoxine neuropathy.
Topics: Adult; Chronic Disease; Diagnosis, Differential; Female; Humans; Neural Conduction; Peripheral Nervo | 1987 |
[Relations between polyneuropathies produced by certain modern drugs, by malabsorption and by malnutrition].
Topics: Animals; Isoniazid; Malabsorption Syndromes; Nitrofurans; Peripheral Nervous System Diseases; Polyne | 1969 |
Neurological disorders and adult coeliac disease.
Topics: Action Potentials; Adult; Aged; Anemia; Calcium; Celiac Disease; Depression; Diet; Epilepsy; Female; | 1970 |
[Action of the pyridoxine-hydroxocobalamin combination in high doses in peripheral neuropathies].
Topics: Humans; Hydroxocobalamin; Injections, Intramuscular; Peripheral Nervous System Diseases; Pyridoxine | 1971 |
Isoniazid: a review with emphasis on adverse effects.
Topics: Anemia, Hemolytic; Chemical and Drug Induced Liver Injury; Desensitization, Immunologic; Drug Hypers | 1972 |
Peripheral neuropathy secondary to isoniazid-induced pyridoxine deficiency.
Topics: Humans; Isoniazid; Male; Middle Aged; Peripheral Nervous System Diseases; Pyridoxine; Vitamin B 6 De | 1972 |
Methionine metabolism in pyridoxine deficiency.
Topics: Adult; Aspartate Aminotransferases; Cystathionine; Cysteine; Erythrocytes; Humans; Lyases; Male; Met | 1974 |