Page last updated: 2024-10-20

pyridoxine and Neuronal Ceroid-Lipofuscinoses

pyridoxine has been researched along with Neuronal Ceroid-Lipofuscinoses in 1 studies

4,5-bis(hydroxymethyl)-2-methylpyridin-3-ol: structure in first source
vitamin B6 : Any member of the group of pyridines that exhibit biological activity against vitamin B6 deficiency. Vitamin B6 deficiency is associated with microcytic anemia, electroencephalographic abnormalities, dermatitis with cheilosis (scaling on the lips and cracks at the corners of the mouth) and glossitis (swollen tongue), depression and confusion, and weakened immune function. Vitamin B6 consists of the vitamers pyridoxine, pyridoxal, and pyridoxamine and their respective 5'-phosphate esters (and includes their corresponding ionized and salt forms).

Neuronal Ceroid-Lipofuscinoses: A group of severe neurodegenerative diseases characterized by intracellular accumulation of autofluorescent wax-like lipid materials (CEROID; LIPOFUSCIN) in neurons. There are several subtypes based on mutations of the various genes, time of disease onset, and severity of the neurological defects such as progressive DEMENTIA; SEIZURES; and visual failure.

Research Excerpts

ExcerptRelevanceReference
"Five patients with Juvenile and one with Infantile Neuronal Ceroid Lipofuscinosis were treated with antioxidants along with vitamins E, B2 and B6, but this treatment did not affect significantly the concentration of iron in the mononuclear cells."1.28Altered elemental profiles in neuronal ceroid lipofuscinosis. ( Heiskala, H; Johansson, E; Lindh, U; Santavuori, P; Westermarck, T, 1990)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Johansson, E1
Lindh, U1
Westermarck, T1
Heiskala, H1
Santavuori, P1

Other Studies

1 other study available for pyridoxine and Neuronal Ceroid-Lipofuscinoses

ArticleYear
Altered elemental profiles in neuronal ceroid lipofuscinosis.
    Journal of trace elements and electrolytes in health and disease, 1990, Volume: 4, Issue:3

    Topics: Adolescent; Antioxidants; Blood Platelets; Calcium; Child; Copper; Female; Humans; Iron; Leukocytes,

1990