pyridoxine has been researched along with Neuroleptic Malignant Syndrome in 1 studies
4,5-bis(hydroxymethyl)-2-methylpyridin-3-ol: structure in first source
vitamin B6 : Any member of the group of pyridines that exhibit biological activity against vitamin B6 deficiency. Vitamin B6 deficiency is associated with microcytic anemia, electroencephalographic abnormalities, dermatitis with cheilosis (scaling on the lips and cracks at the corners of the mouth) and glossitis (swollen tongue), depression and confusion, and weakened immune function. Vitamin B6 consists of the vitamers pyridoxine, pyridoxal, and pyridoxamine and their respective 5'-phosphate esters (and includes their corresponding ionized and salt forms).
Neuroleptic Malignant Syndrome: A potentially fatal syndrome associated primarily with the use of neuroleptic agents (see ANTIPSYCHOTIC AGENTS) which are in turn associated with dopaminergic receptor blockade (see RECEPTORS, DOPAMINE) in the BASAL GANGLIA and HYPOTHALAMUS, and sympathetic dysregulation. Clinical features include diffuse MUSCLE RIGIDITY; TREMOR; high FEVER; diaphoresis; labile blood pressure; cognitive dysfunction; and autonomic disturbances. Serum CPK level elevation and a leukocytosis may also be present. (From Adams et al., Principles of Neurology, 6th ed, p1199; Psychiatr Serv 1998 Sep;49(9):1163-72)
| Excerpt | Relevance | Reference |
|---|---|---|
| "We present a case of a 74-year-old patient with schizoaffective disorder, who developed risperidone-related neuroleptic malignant syndrome." | 7.70 | High-dose vitamin E plus vitamin B6 treatment of risperidone-related neuroleptic malignant syndrome. ( Devarajan, S; Dursun, SM; Kutcher, SP; Oluboka, OJ, 1998) |
| "We present a case of a 74-year-old patient with schizoaffective disorder, who developed risperidone-related neuroleptic malignant syndrome." | 3.70 | High-dose vitamin E plus vitamin B6 treatment of risperidone-related neuroleptic malignant syndrome. ( Devarajan, S; Dursun, SM; Kutcher, SP; Oluboka, OJ, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Dursun, SM | 1 |
| Oluboka, OJ | 1 |
| Devarajan, S | 1 |
| Kutcher, SP | 1 |
1 other study available for pyridoxine and Neuroleptic Malignant Syndrome
| Article | Year |
|---|---|
High-dose vitamin E plus vitamin B6 treatment of risperidone-related neuroleptic malignant syndrome.
Topics: Aged; Antipsychotic Agents; Drug Therapy, Combination; Female; Humans; Neuroleptic Malignant Syndrom | 1998 |