Page last updated: 2024-10-20

pyridoxine and Neurodegenerative Diseases

pyridoxine has been researched along with Neurodegenerative Diseases in 4 studies

4,5-bis(hydroxymethyl)-2-methylpyridin-3-ol: structure in first source
vitamin B6 : Any member of the group of pyridines that exhibit biological activity against vitamin B6 deficiency. Vitamin B6 deficiency is associated with microcytic anemia, electroencephalographic abnormalities, dermatitis with cheilosis (scaling on the lips and cracks at the corners of the mouth) and glossitis (swollen tongue), depression and confusion, and weakened immune function. Vitamin B6 consists of the vitamers pyridoxine, pyridoxal, and pyridoxamine and their respective 5'-phosphate esters (and includes their corresponding ionized and salt forms).

Neurodegenerative Diseases: Hereditary and sporadic conditions which are characterized by progressive nervous system dysfunction. These disorders are often associated with atrophy of the affected central or peripheral nervous system structures.

Research Excerpts

ExcerptRelevanceReference
" An orally bioavailable GCP II inhibitor, 2-(3-mercaptopropyl) pentanedioic acid (2-MPPA), was administered daily at a dose of 30 mg/kg starting from the onset of pyridoxine injections."1.40Glutamate carboxypeptidase II inhibition behaviorally and physiologically improves pyridoxine-induced neuropathy in rats. ( Callizot, N; Potter, MC; Slusher, BS; Wozniak, KM, 2014)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (75.00)29.6817
2010's1 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Potter, MC1
Wozniak, KM1
Callizot, N1
Slusher, BS1
Perry, TA1
Weerasuriya, A1
Mouton, PR1
Holloway, HW1
Greig, NH1
Chung, JY1
Choi, JH1
Hwang, CY1
Youn, HY1
Diaz-Arrastia, R1

Reviews

1 review available for pyridoxine and Neurodegenerative Diseases

ArticleYear
Homocysteine and neurologic disease.
    Archives of neurology, 2000, Volume: 57, Issue:10

    Topics: Brain Diseases; Epilepsy; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Neurodegenerative

2000

Other Studies

3 other studies available for pyridoxine and Neurodegenerative Diseases

ArticleYear
Glutamate carboxypeptidase II inhibition behaviorally and physiologically improves pyridoxine-induced neuropathy in rats.
    PloS one, 2014, Volume: 9, Issue:9

    Topics: Animals; Behavior, Animal; Female; Glutamate Carboxypeptidase II; Glutarates; Motor Activity; Neurod

2014
Pyridoxine-induced toxicity in rats: a stereological quantification of the sensory neuropathy.
    Experimental neurology, 2004, Volume: 190, Issue:1

    Topics: Animals; Cell Count; Cell Size; Disease Models, Animal; Disease Progression; Electrophysiology; Gang

2004
Pyridoxine induced neuropathy by subcutaneous administration in dogs.
    Journal of veterinary science, 2008, Volume: 9, Issue:2

    Topics: Animals; Body Weight; Disease Models, Animal; Dogs; Electrophysiology; Neurodegenerative Diseases; P

2008