pyridoxine has been researched along with Nerve Degeneration in 7 studies
4,5-bis(hydroxymethyl)-2-methylpyridin-3-ol: structure in first source
vitamin B6 : Any member of the group of pyridines that exhibit biological activity against vitamin B6 deficiency. Vitamin B6 deficiency is associated with microcytic anemia, electroencephalographic abnormalities, dermatitis with cheilosis (scaling on the lips and cracks at the corners of the mouth) and glossitis (swollen tongue), depression and confusion, and weakened immune function. Vitamin B6 consists of the vitamers pyridoxine, pyridoxal, and pyridoxamine and their respective 5'-phosphate esters (and includes their corresponding ionized and salt forms).
Nerve Degeneration: Loss of functional activity and trophic degeneration of nerve axons and their terminal arborizations following the destruction of their cells of origin or interruption of their continuity with these cells. The pathology is characteristic of neurodegenerative diseases. Often the process of nerve degeneration is studied in research on neuroanatomical localization and correlation of the neurophysiology of neural pathways.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (42.86) | 18.7374 |
| 1990's | 2 (28.57) | 18.2507 |
| 2000's | 1 (14.29) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (14.29) | 2.80 |
| Authors | Studies |
|---|---|
| Theil, D | 1 |
| Kuhle, J | 1 |
| Brees, D | 1 |
| Tritto, E | 1 |
| Pognan, F | 1 |
| Frieauff, W | 1 |
| Penraat, K | 1 |
| Meseck, E | 1 |
| Valdez, R | 1 |
| Hartmann, A | 1 |
| Krinke, G | 2 |
| Schaumburg, HH | 1 |
| Spencer, PS | 1 |
| Suter, J | 1 |
| Thomann, P | 1 |
| Hess, R | 1 |
| Perry, T | 1 |
| Holloway, HW | 1 |
| Weerasuriya, A | 1 |
| Mouton, PR | 1 |
| Duffy, K | 1 |
| Mattison, JA | 1 |
| Greig, NH | 1 |
| Yamamoto, T | 1 |
| Becker, KW | 1 |
| Kienecker, EW | 1 |
| Dick, P | 1 |
| Schaeppi, U | 1 |
| Castellano, MA | 1 |
| Tórtora, JL | 1 |
| Germino, NI | 1 |
| Rama, F | 1 |
| Ohanian, C | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Long-acting Exenatide: a Tool to Stop Cognitive Decline in Dysglycemic Patients With Mild Cognitive Impairment?[NCT02847403] | Phase 3 | 40 participants (Anticipated) | Interventional | 2016-02-29 | Active, not recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
7 other studies available for pyridoxine and Nerve Degeneration
| Article | Year |
|---|---|
Neurofilament Light Chain: A Translational Safety Biomarker for Drug-Induced Peripheral Neurotoxicity.
Topics: Animals; Biomarkers; Dogs; Intermediate Filaments; Nerve Degeneration; Neurotoxicity Syndromes; Pyri | 2023 |
Pyridoxine megavitaminosis produces degeneration of peripheral sensory neurons (sensory neuronopathy) in the dog.
Topics: Animals; Dogs; Female; Male; Nerve Degeneration; Neurons, Afferent; Neurotoxicity Syndromes; Pyridox | 1981 |
Evidence of GLP-1-mediated neuroprotection in an animal model of pyridoxine-induced peripheral sensory neuropathy.
Topics: Amino Acid Sequence; Animals; Behavior, Animal; Blood Glucose; Body Weight; Exenatide; Ganglia, Spin | 2007 |
[Pathologic processes of lumbar primary sensory neurons produced by high doses of pyridoxine in rats--morphometric and electron microscopic studies].
Topics: Animals; Male; Microscopy, Electron; Nerve Degeneration; Nerve Fibers, Myelinated; Neurons, Afferent | 1991 |
A contribution to the scientific assessment of degenerative and regenerative processes of peripheral nerve fibers following axonotmesis under the systemic administration of vitamins B1, B6 and B12--light and electron microscopy findings of the saphenous n
Topics: Animals; Axons; Dose-Response Relationship, Drug; Hindlimb; Microscopy, Electron; Nerve Degeneration | 1990 |
Differential vulnerability of 3 rapidly conducting somatosensory pathways in the dog with vitamin B6 neuropathy.
Topics: Animals; Dogs; Electric Stimulation; Evoked Potentials, Somatosensory; Female; Locomotion; Muscle Co | 1985 |
The effects of isonicotinic acid hydrazide on the early chick embryo.
Topics: Abnormalities, Drug-Induced; Animals; Chick Embryo; Epithelium; Isoniazid; Nerve Degeneration; Neuro | 1973 |