Page last updated: 2024-10-20

pyridoxine and Neoplasms

pyridoxine has been researched along with Neoplasms in 55 studies

4,5-bis(hydroxymethyl)-2-methylpyridin-3-ol: structure in first source
vitamin B6 : Any member of the group of pyridines that exhibit biological activity against vitamin B6 deficiency. Vitamin B6 deficiency is associated with microcytic anemia, electroencephalographic abnormalities, dermatitis with cheilosis (scaling on the lips and cracks at the corners of the mouth) and glossitis (swollen tongue), depression and confusion, and weakened immune function. Vitamin B6 consists of the vitamers pyridoxine, pyridoxal, and pyridoxamine and their respective 5'-phosphate esters (and includes their corresponding ionized and salt forms).

Neoplasms: New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.

Research Excerpts

ExcerptRelevanceReference
"Hand-foot syndrome (HFS) is a common adverse effect of capecitabine treatment."9.24Predictors of Hand-Foot Syndrome and Pyridoxine for Prevention of Capecitabine-Induced Hand-Foot Syndrome: A Randomized Clinical Trial. ( Chay, WY; Chia, JWK; Choo, SP; Dent, RA; Koh, KX; Koo, WH; Kwok, LL; Lo, SK; Loh, M; Mok, ZY; Ng, RCH; Soong, RCT; Syn, N; Tan, S; Tham, CK; Toh, HC; Wong, NS; Yap, YS, 2017)
"Doxylamine-pyridoxine is the first-line agent for the treatment of nausea and vomiting of pregnancy (NVP) according to Canadian guidelines, and this combination is commonly prescribed to pregnant women."7.80Should doxylamine-pyridoxine be used for nausea and vomiting of pregnancy? ( Chin, J; Persaud, N; Walker, M, 2014)
"Hand-foot syndrome (HFS) is a common adverse effect of capecitabine treatment."5.24Predictors of Hand-Foot Syndrome and Pyridoxine for Prevention of Capecitabine-Induced Hand-Foot Syndrome: A Randomized Clinical Trial. ( Chay, WY; Chia, JWK; Choo, SP; Dent, RA; Koh, KX; Koo, WH; Kwok, LL; Lo, SK; Loh, M; Mok, ZY; Ng, RCH; Soong, RCT; Syn, N; Tan, S; Tham, CK; Toh, HC; Wong, NS; Yap, YS, 2017)
"Doxylamine-pyridoxine is the first-line agent for the treatment of nausea and vomiting of pregnancy (NVP) according to Canadian guidelines, and this combination is commonly prescribed to pregnant women."3.80Should doxylamine-pyridoxine be used for nausea and vomiting of pregnancy? ( Chin, J; Persaud, N; Walker, M, 2014)
"Pyridoxine deficiency and 4'-deoxypyridoxine produce acrodynia in rats and seborrheic dermatitis in man."3.67Pyridoxine deficiency and antagonism produce increased ground substance viscosity with resulting seborrheic dermatitis and increased tumor resistance. ( Stone, OJ, 1989)
"Celecoxib was effective in preventing HFS in patients who received capecitabine (50."2.82Prophylactic strategies for hand-foot syndrome/skin reaction associated with systemic cancer treatment: a meta-analysis of randomized controlled trials. ( Franco, PIG; Li, RK; Pandy, JGP, 2022)
"Subclinical riboflavin deficiency impairs psychomotor function and vitamin B2 requirement may be enhanced during increased physical activity."2.40Riboflavin metabolism--relevance to human nutrition. ( Lakshmi, AV, 1998)
"Diet has been associated with cancer, heart disease, diabetes, stroke and hypertension, arteriosclerosis, and cirrhosis of the liver."2.37Implications of nutritional status on human biochemistry, physiology, and health. ( Sauberlich, HE, 1984)
" No dose-response relationship was evident."1.27Inter-Regional Epidemiological Study of Childhood Cancer (IRESCC): childhood cancer and the consumption of debendox and related drugs in pregnancy. ( Birch, JM; Cartwright, RA; Hartley, AL; Hopton, PA; Johnston, HE; Mann, JR; McKinney, PA; Stiller, CA; Waterhouse, JA, 1985)

Research

Studies (55)

TimeframeStudies, this research(%)All Research%
pre-199043 (78.18)18.7374
1990's3 (5.45)18.2507
2000's3 (5.45)29.6817
2010's4 (7.27)24.3611
2020's2 (3.64)2.80

Authors

AuthorsStudies
Pandy, JGP1
Franco, PIG1
Li, RK1
Charalambous, A1
Tsitsi, T1
Astras, G1
Paikousis, L1
Filippou, E1
Gay, F1
Aguera, K1
Sénéchal, K1
Tainturier, A1
Berlier, W1
Maucort-Boulch, D1
Honnorat, J1
Horand, F1
Godfrin, Y1
Bourgeaux, V1
Yap, YS1
Kwok, LL1
Syn, N1
Chay, WY1
Chia, JWK1
Tham, CK1
Wong, NS1
Lo, SK1
Dent, RA1
Tan, S1
Mok, ZY1
Koh, KX1
Toh, HC1
Koo, WH1
Loh, M1
Ng, RCH1
Choo, SP1
Soong, RCT1
Persaud, N1
Chin, J1
Walker, M1
Lipka, D1
Boratyński, J1
TATUM, EL1
RITCHEY, MG1
MILLER, EC2
BAUMANN, CA1
RUSCH, HP1
Yamaguchi, A1
Ogino, Y1
Iwakoshi, C1
Karasawa, K1
Ohki, M1
TEDESCHI, GG1
IWATSURU, R1
KAWATA, H1
MASUDA, T1
IKEDA, T1
KAWATA, Y1
BERENBAUM, MC1
BARTH, G1
DRECHSEL, H1
GRAEBNER, H1
FARRERASVALENTI, P1
ROZMAN, C1
WOESSNER, S1
AKSENOVA, OV1
VEENEMA, RJ1
FINGERHUT, B1
TANNENBAUM, M1
MELICOW, MM1
USON, AC1
PRICE, TD1
HOLTZ, P1
PALM, D1
LEVY, C1
LUSSANA, S1
ITO, K1
NAKAHARA, I1
SAKAMOTO, Y1
STOERK, HC1
SCHAEFER, AE1
COPELAND, DH1
SALMON, WD1
HALE, OM1
LOEFER, JB1
GELLHORN, A1
JONES, LO1
PRICE, JM1
MILLER, JA1
von Moos, R1
Thuerlimann, BJ1
Aapro, M1
Rayson, D1
Harrold, K1
Sehouli, J1
Scotte, F1
Lorusso, D1
Dummer, R1
Lacouture, ME1
Lademann, J1
Hauschild, A1
Pipino, G1
Raffaglio, E1
Dickerson, JW1
Sauberlich, HE1
Miyamoto, H1
Kokiya, T1
Kosuda, S1
Hashimoto, S1
Yasu, T1
Katayama, M1
Suzuki, S1
Yoshioka, T1
Masaki, E1
Kinoshita, F1
Maekawa, A1
Izumi, K1
Takada, I1
Tanaka, Y1
Ladner, HA2
Mitchell, JS1
King, EA1
Weisselberg, R1
Tryfiates, GP1
Gannett, PM1
Bishop, RE1
Shastri, PK1
Ammons, JR1
Arbogast, JG1
Lakshmi, AV1
Mason, RP1
Poirier, LA1
Wise, CK1
Delongchamp, RR1
Sinha, R1
Korzon, M1
Korzon, T1
Stone, OJ1
Chuvykin, MB1
Fortmeyer, HP1
Salkeld, RM1
Merrill, AH1
Henderson, JM1
Reynolds, RD1
McKinney, PA1
Cartwright, RA1
Stiller, CA1
Hopton, PA1
Mann, JR1
Birch, JM1
Hartley, AL1
Waterhouse, JA1
Johnston, HE1
Warburg, O1
Geissler, AW1
Lorenz, S1
Khristov, I1
Donchev, T1
Karlin, R1
Croizat, P1
Revol, L1
Pommatau, E1
Viala, JJ1
Dumont, M1
Raushenbakh, MO1
Kärcher, KH1
Holt, JA1
Coon, WW1
Nagler, E1
Mocchi, N1
Pollini, F1
Nichol, CA1
Gailani, SD1
Holland, JF1
Nussbaum, A1
Olson, KB1
Sicher, K1
Backhouse, TW1

Clinical Trials (5)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Double Blind Placebo Control Randomised Trial to Test the Effectiveness of Vitamin B6 in Hand Foot Syndrome[NCT02625415]54 participants (Actual)Interventional2016-07-31Completed
Randomized Double-Blind Placebo-Controlled Trial of Pyridoxine for Prevention of Capecitabine-Induced Hand-Foot Syndrome (HFS)[NCT00486213]Phase 3210 participants (Actual)Interventional2007-06-30Terminated (stopped due to Slow accrual)
Effect of Topical Diclofenac on Clinical Outcome in Breast Cancer Patients Treated With Capecitabine: A Randomized Controlled Trial.[NCT05641246]Phase 266 participants (Anticipated)Interventional2022-12-08Active, not recruiting
Prevalence and Burden of Nausea and Vomiting in Pregnant Women in Switzerland: Survey Purity 2022[NCT06055192]200 participants (Anticipated)Observational2023-09-30Not yet recruiting
Double-blind, Prospective Comparison of Medications Used in Trigger Point Injections - Ketorolac, Lidocaine, or Dexamethasone[NCT03028012]Phase 410 participants (Actual)Interventional2017-05-02Terminated (stopped due to Poor enrollment.)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Number of Participants With a Responder Rate Greater Than 50% on the Numeric Rating Pain Scale (NRS) Improvement

Participants in this study underwent TPIs by the following method. The needle was inserted into the trigger point with the goal of eliciting a local twitch responses(LTRs). When a LTR was obtained, 0.1mL of randomized drug was injected into that location within the muscle. This was repeated until LTRs disappeared, or 1.0mL had been injected, whichever came first. This was performed in a similar manner for all affected muscles, up to a maximum of 2mL. Participants self-report their brief pain inventory at each of their injections (up to four subsequent injections) based off of the standardized Numeric Rating pain Scale (NRS). The NRS is nationally recognized numeric scale from zero to ten, with zero being an example of no pain, one to three would demonstrate mild pain, four to six would be moderate pain, seven to nine would be severe pain and a ten would be the worst pain possible. Improvement in BPI was determined if their NRS score went down with each injection(s). (NCT03028012)
Timeframe: Pre-Post Injections Up to Three Months

InterventionParticipants (Count of Participants)
Ketorolac1
Lidocaine0
Dexamethasone0

Brief Pain Inventory (BPI) - Modified

The BPI was evaluated on a scale from 0-10. Zero would mean no interference and 10 would be calculated at complete interferences. We used a 7-point questionnaire about pain. All scores were calculated at baseline and three months. (NCT03028012)
Timeframe: Baseline and Three Months

Interventionscore on a scale (Number)
Participant Number #3 at BaselineParticipant Number #3 at 3 MonthsParticipant Number #8 at BaselineParticipant #8 at 3 Months
Ketorolac8353

Numeric Rating Pain Scale (NRS) at Baseline and Three Months.

TPI were treated with a needle inserted into the trigger point with the goal of eliciting a local twitch responses(LTRs). When a LTR was obtained, 0.1mL of randomized drug was injected into that location within the muscle. This was repeated until LTRs disappeared, or 1.0mL had been injected, whichever came first. Such was performed in a similar manner for all affected muscles, up to a maximum of 2mL. Participants self-report their brief pain inventory at each of their injections (up to four subsequent injections) based off of the standardized Numeric Rating pain Scale (NRS). The NRS is nationally recognized numeric scale from zero to ten, with zero being an example of no pain,one to three would demonstrate mild pain, four to six would be moderate pain, seven to nine would be severe pain and a ten would be the worst pain possible. Improvement in BPI was determined if their NRS score went down with each injection(s). (NCT03028012)
Timeframe: Pre-Injection and Three Month Post Injection(s)

Interventionscore on a scale (Number)
Participant Number 3 at BaselineParticipant Number 3 at 3 MonthsParticipant Number 8 at BaselineParticipant Number 8 at 3 Months
Ketorolac8353

Reviews

12 reviews available for pyridoxine and Neoplasms

ArticleYear
Prophylactic strategies for hand-foot syndrome/skin reaction associated with systemic cancer treatment: a meta-analysis of randomized controlled trials.
    Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2022, Volume: 30, Issue:11

    Topics: Capecitabine; Celecoxib; Hand-Foot Syndrome; Humans; Neoplasms; Pyridoxine; Randomized Controlled Tr

2022
[Metalloproteinases. Structure and function].
    Postepy higieny i medycyny doswiadczalnej (Online), 2008, Jul-03, Volume: 62

    Topics: 4-Aminobenzoic Acid; Animals; Apoptosis; Arthritis; Autoimmune Diseases; Cell Movement; Chloroquine;

2008
PHARMACOLOGICAL ASPECTS OF VITAMIN B6.
    Pharmacological reviews, 1964, Volume: 16

    Topics: Amino Acids; Antimetabolites; Enzymes; Fatty Acids; Humans; Lipid Metabolism; Metabolism; Neoplasms;

1964
Nutrition of the cancer patient.
    Advances in nutritional research, 1983, Volume: 5

    Topics: Anorexia; Ascorbic Acid; Cachexia; Drug-Related Side Effects and Adverse Reactions; Enteral Nutritio

1983
Implications of nutritional status on human biochemistry, physiology, and health.
    Clinical biochemistry, 1984, Volume: 17, Issue:2

    Topics: Alcoholism; Anemia, Hypochromic; Animals; Ascorbic Acid; Avitaminosis; Climate; Dietary Fats; Female

1984
Riboflavin metabolism--relevance to human nutrition.
    The Indian journal of medical research, 1998, Volume: 108

    Topics: Diabetes Mellitus; Female; Humans; Neoplasms; Nutrition Disorders; Pregnancy; Pyridoxine; Respirator

1998
Transmembrane pH gradients in vivo: measurements using fluorinated vitamin B6 derivatives.
    Current medicinal chemistry, 1999, Volume: 6, Issue:6

    Topics: Animals; Fluorescence; Fluorine Radioisotopes; Forecasting; Humans; Hydrogen-Ion Concentration; Magn

1999
[Clinical importance of tryptophan metabolism disorders].
    Polski tygodnik lekarski (Warsaw, Poland : 1960), 1978, May-08, Volume: 33, Issue:19

    Topics: Amino Acid Metabolism, Inborn Errors; Hartnup Disease; Humans; Neoplasms; Pyridoxine; Tryptophan; Tr

1978
[The role of vitamin B6 in tumor growth].
    Eksperimental'naia onkologiia, 1989, Volume: 11, Issue:5

    Topics: Animals; Humans; Neoplasms; Polyamines; Pyridoxine; Tetrahydrofolates; Thymidylate Synthase

1989
Vitamin B6 status in cancer patients: effect of tumor site, irradiation, hormones and chemotherapy.
    Progress in clinical and biological research, 1988, Volume: 259

    Topics: Breast Neoplasms; Estrogens; Female; Genital Neoplasms, Female; Humans; Neoplasms; Ovarian Neoplasms

1988
Diseases associated with defects in vitamin B6 metabolism or utilization.
    Annual review of nutrition, 1987, Volume: 7

    Topics: Alkaline Phosphatase; Arteriosclerosis; Celiac Disease; Female; Hematologic Diseases; Humans; Kidney

1987
[Mechanism of the formation and accumulation of blastomogenic (leukozogenic) metabolites of tryptophan].
    Problemy gematologii i perelivaniia krovi, 1969, Volume: 14, Issue:11

    Topics: Animals; Carcinogens; Drosophila; Female; Humans; Indican; Indoleacetic Acids; Indoles; Leukemia; Le

1969

Trials

3 trials available for pyridoxine and Neoplasms

ArticleYear
A pilot randomized double-blind, placebo-controlled study on the effects of the topical application of pyridoxine on palmar-plantar erythrodysesthesia (PPE) induced by capecitabine or pegylated liposomal doxorubicin (PLD).
    European journal of oncology nursing : the official journal of European Oncology Nursing Society, 2021, Volume: 50

    Topics: Activities of Daily Living; Administration, Topical; Adult; Aged; Antibiotics, Antineoplastic; Antim

2021
Predictors of Hand-Foot Syndrome and Pyridoxine for Prevention of Capecitabine-Induced Hand-Foot Syndrome: A Randomized Clinical Trial.
    JAMA oncology, 2017, Nov-01, Volume: 3, Issue:11

    Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Asian People; Capecitabine; Chi-Squ

2017
Predictors of Hand-Foot Syndrome and Pyridoxine for Prevention of Capecitabine-Induced Hand-Foot Syndrome: A Randomized Clinical Trial.
    JAMA oncology, 2017, Nov-01, Volume: 3, Issue:11

    Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Asian People; Capecitabine; Chi-Squ

2017
Predictors of Hand-Foot Syndrome and Pyridoxine for Prevention of Capecitabine-Induced Hand-Foot Syndrome: A Randomized Clinical Trial.
    JAMA oncology, 2017, Nov-01, Volume: 3, Issue:11

    Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Asian People; Capecitabine; Chi-Squ

2017
Predictors of Hand-Foot Syndrome and Pyridoxine for Prevention of Capecitabine-Induced Hand-Foot Syndrome: A Randomized Clinical Trial.
    JAMA oncology, 2017, Nov-01, Volume: 3, Issue:11

    Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Asian People; Capecitabine; Chi-Squ

2017
An assessment of thiethylperazine (Torecan) in the control of radiation-induced nausea and vomiting.
    Clinical radiology, 1968, Volume: 19, Issue:2

    Topics: Antiemetics; Humans; Nausea; Neoplasms; Pyridoxine; Radiotherapy; Thiethylperazine; Vomiting

1968

Other Studies

40 other studies available for pyridoxine and Neoplasms

ArticleYear
Methionine tumor starvation by erythrocyte-encapsulated methionine gamma-lyase activity controlled with per os vitamin B6.
    Cancer medicine, 2017, Volume: 6, Issue:6

    Topics: Animals; Antineoplastic Agents; Carbon-Sulfur Lyases; Cell Line, Tumor; Cell Proliferation; Cell Sur

2017
Should doxylamine-pyridoxine be used for nausea and vomiting of pregnancy?
    Journal of obstetrics and gynaecology Canada : JOGC = Journal d'obstetrique et gynecologie du Canada : JOGC, 2014, Volume: 36, Issue:4

    Topics: Abnormalities, Drug-Induced; Antiemetics; Dicyclomine; Doxylamine; Drug Combinations; Female; Humans

2014
Vitamin content of mouse epidermis during methylcholanthrene carcinogenesis; biotin, choline, inositol, rho-aminobenzoic acid, and pyridoxine.
    The Journal of biological chemistry, 1946, Volume: 163

    Topics: 4-Aminobenzoic Acid; Acids; Biotin; Carcinogenesis; Choline; Epidermis; Inositol; Methylcholanthrene

1946
Certain effects of dietery pyridoxine and casein on the carcinogenicity of P-dime-thylaminoazobenzene.
    Cancer research, 1945, Volume: 5

    Topics: Azo Compounds; Caseins; Humans; Neoplasms; Pyridoxine

1945
[Trigger point therapy for myofascial pain in cancer patients (second report) analysis results of special use-results surveillance by neovitacain® injection].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2012, Volume: 39, Issue:4

    Topics: Dibucaine; Humans; Injections; Myofascial Pain Syndromes; Neoplasms; Pyridoxine; Sodium Salicylate;

2012
[Effect of pyridoxine phosphoric esters and of desoxypyridoxine on benzopyrene induced sarcoma in rat].
    Tumori, 1952, Volume: 38, Issue:6

    Topics: Animals; Benzopyrenes; Esters; Neoplasms; Pyridoxine; Rats; Sarcoma; Sarcoma, Experimental; Vitamin

1952
[Studies on the biochemical changes during experimental carcinogenesis. I. The effects of pyridoxine and glutamic acid].
    Gan, 1957, Volume: 48, Issue:4

    Topics: Carcinogenesis; Glutamates; Glutamic Acid; Neoplasms; Pyridoxine; Vitamin B 6

1957
A screen for agents inhibiting the immune response and the growth of tumours.
    Nature, 1962, Oct-27, Volume: 196

    Topics: Alloxan; Anti-Bacterial Agents; Antibiotics, Antitubercular; Antibody Formation; Antineoplastic Agen

1962
[ADDITIONAL DRUG TREATMENT OF TUMOR BEDS. V. ON THE EFFECT OF PYRIDOXINE ON TUMOR GROWTH AND SURVIVAL RATE OF MICE OF THE INBRED NMRI STRAIN IN THE RADIOTHERAPY OF EXPERIMENTAL TUMORS].
    Strahlentherapie, 1963, Volume: 121

    Topics: Animals; Animals, Laboratory; Mice; Neoplasms; Neoplasms, Experimental; Pyridoxine; Research; Sarcom

1963
[PRENEOPLASTIC, SIDEROBLASTIC REFRACTORY ANEMIAS].
    Revista clinica espanola, 1964, Jan-15, Volume: 92

    Topics: Abdominal Neoplasms; Anemia; Anemia, Refractory; Anemia, Sideroblastic; Cecal Neoplasms; Humans; Leu

1964
[DETERMINATION OF VITAMINS OF THE B6 GROUP BY ELECTROPHORESIS ON PAPER].
    Laboratornoe delo, 1964, Volume: 10

    Topics: Electrophoresis; Humans; Leukemia; Liver Cirrhosis; Neoplasms; Pyridoxine; Vitamin A; Vitamin K; Vit

1964
THE EFFECT OF GONADECTOMY ON THE EXPERIMENTAL PRODUCTION OF BLADDER CARCINOMA IN THE FISCHER RAT (F-FU).
    Investigative urology, 1964, Volume: 1

    Topics: Animals; Castration; Diet; Fluorenes; Humans; Male; Neoplasms; Neoplasms, Experimental; Orchiectomy;

1964
BLADDER TUMOR INDUCTION IN RATS FED 2-ACETAMIDOFLUORENE (2-AAF) AND A PYRIDOXINE-DEFICIENT DIET.
    The Journal of urology, 1964, Volume: 91

    Topics: 2-Acetylaminofluorene; Carcinogens; Diet; Fluorenes; Liver; Liver Cirrhosis; Liver Cirrhosis, Experi

1964
[PRACTICAL APPLICATIONS OF PYRIDOSCORBINE].
    Clinique (Paris, France), 1964, Volume: 59

    Topics: Alcoholism; Ascorbic Acid; Drug Synergism; Drug Therapy; Fatigue; Geriatrics; Humans; Neoplasms; Pyr

1964
[CLINICAL OBSERVATIONS ON THE SUBJECT OF VITAMIN THERAPY].
    La Clinica terapeutica, 1964, Dec-15, Volume: 31

    Topics: Alcoholism; Drug Therapy; Humans; Kidney Diseases; Liver Cirrhosis; Neoplasms; Pyridoxine; Thiamine;

1964
[STUDIES ON VITAMIN B6 METABOLISM OF CANCER CELLS AND TUMOR-BEARING RAT LIVER. II. UPTAKE OF PYRIDOXINE DERIVATIVES BY TUMOR CELLS AND THE LIVER OF TUMOR-BEARING RATS].
    Gan, 1964, Volume: 55

    Topics: Carcinoma, Hepatocellular; Liver; Liver Neoplasms; Neoplasms; Neoplasms, Experimental; Permeability;

1964
Growth retardation of lymphosarcoma implants in pyridoxine deficient rats by testosterone and cortisone.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1950, Volume: 74, Issue:4

    Topics: Androgens; Animals; Cortisone; Lymphoma; Lymphoma, Non-Hodgkin; Neoplasms; Pyridoxine; Rats; Sarcoma

1950
The influence of riboflavin, pyridoxine, inositol, and protein depletion- repletion upon the induction of neoplasms by choline deficiency.
    Cancer research, 1950, Volume: 10, Issue:12

    Topics: Choline Deficiency; Folic Acid; Humans; Inositol; Neoplasms; Pyridoxine; Riboflavin; Vitamin B Compl

1950
Effect of pyridoxine and desoxypyridoxine on rat fibrosarcoma grafts.
    Cancer research, 1951, Volume: 11, Issue:7

    Topics: Fibrosarcoma; Neoplasms; Pyridoxine; Sarcoma; Vitamin B 6

1951
Pyridoxine deficient diet and desoxypyridoxine in the therapy of lymphosarcoma and acute leukemia in man.
    Blood, 1949, Volume: 4, Issue:1

    Topics: Diet; Humans; Leukemia; Lymphoma; Lymphoma, Non-Hodgkin; Male; Neoplasms; Pyridoxine

1949
Intracellular distribution of vitamin B6 in rat and mouse livers and induced rat liver tumors.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1949, Volume: 71, Issue:4

    Topics: Animals; Cytoplasm; Liver; Mice; Neoplasms; Neoplasms, Experimental; Pyridoxine; Rats; Vitamin B 6

1949
Pegylated liposomal doxorubicin-associated hand-foot syndrome: recommendations of an international panel of experts.
    European journal of cancer (Oxford, England : 1990), 2008, Volume: 44, Issue:6

    Topics: Adrenal Cortex Hormones; Dermatologic Agents; Doxorubicin; Drug Eruptions; Erythema; Foot Dermatoses

2008
[Treatment of the secondary collateral toxic effects of antiblastic drugs].
    Minerva medica, 1967, Dec-15, Volume: 58, Issue:100

    Topics: Adrenal Glands; Antineoplastic Agents; Asthenia; Headache; Humans; Hypotension; Nausea; Neoplasms; P

1967
[The effect of Neolamin 3B to the anemia of cancer patients (author's transl)].
    Rinsho hoshasen. Clinical radiography, 1981, Volume: 26, Issue:6

    Topics: Anemia; Drug Therapy, Combination; Humans; Neoplasms; Pyridoxine; Thiamine; Vitamin B 12; Vitamin B

1981
[Influence of vitamins of the B-group upon cancer patients treated by irradiation: I. Vitamin B6 in local irradiation of tumour rats (author's transl)].
    Strahlentherapie, 1980, Volume: 156, Issue:12

    Topics: Animals; Female; Male; Neoplasms; Pyridoxine; Radiation-Protective Agents; Radiotherapy Dosage; Rats

1980
Vitamin B6 and cancer: synthesis and occurrence of adenosine-N6-diethylthioether-N-pyridoximine-5'-phosphate, a circulating human tumor marker.
    Cancer research, 1996, Aug-15, Volume: 56, Issue:16

    Topics: Adenosine; Animals; Biomarkers, Tumor; Humans; Hydrogen-Ion Concentration; Neoplasms; Pyridoxine; Ra

1996
Blood determinations of S-adenosylmethionine, S-adenosylhomocysteine, and homocysteine: correlations with diet.
    Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2001, Volume: 10, Issue:6

    Topics: Body Mass Index; Diet; Dietary Fats; Erythrocytes; Female; Folic Acid; Homocysteine; Humans; Male; N

2001
Pyridoxine deficiency and antagonism produce increased ground substance viscosity with resulting seborrheic dermatitis and increased tumor resistance.
    Medical hypotheses, 1989, Volume: 30, Issue:4

    Topics: Acrodynia; Animals; Dermatitis, Seborrheic; Humans; Inflammation; Models, Biological; Neoplasms; Pyr

1989
Possible consequences of vitamin B6 responsive growth in certain malignant tumors of human origin.
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 1989, Volume: 165, Issue:7

    Topics: Humans; Neoplasms; Pyridoxine

1989
Vitamin B6 deficiency and carcinogenesis.
    Advances in experimental medicine and biology, 1986, Volume: 206

    Topics: Animals; Humans; Melanoma; Neoplasms; Neoplasms, Experimental; Pyridoxine; Tryptophan; Vitamin B 6 D

1986
Inter-Regional Epidemiological Study of Childhood Cancer (IRESCC): childhood cancer and the consumption of debendox and related drugs in pregnancy.
    British journal of cancer, 1985, Volume: 52, Issue:6

    Topics: Adolescent; Antiemetics; Child; Cyclohexanecarboxylic Acids; Dicyclomine; Dose-Response Relationship

1985
[Genesis of tumor metabolism by vitamin B1 deficiency (thiamine deficiency)].
    Zeitschrift fur Naturforschung. Teil B, Chemie, Biochemie, Biophysik, Biologie und verwandte Gebiete, 1970, Volume: 25, Issue:3

    Topics: Animals; Carbon Dioxide; Chick Embryo; Culture Media; Culture Techniques; NAD; Neoplasms; Oxygen Con

1970
[Treatment of leukopenic and anemic states in patients with malignant neoplasms, treated by chemotherapy and radiation therapy].
    Vutreshni bolesti, 1974, Volume: 13, Issue:1

    Topics: Anemia; Blood Transfusion; Humans; Leukopenia; Neoplasms; Pyridoxine; Vitamin B 12

1974
[Studies on vitamin B6 deficiency during pregnacy and in various pathological states using pyridoxine saturation test].
    Pathologie et biologie, 1968, Volume: 16, Issue:21

    Topics: Anemia, Hypochromic; Anemia, Macrocytic; Anemia, Pernicious; Bone Marrow Diseases; Diabetes Mellitus

1968
[Treatment of local and generalized radiation side-effects].
    Langenbecks Archiv fur Chirurgie, 1969, Volume: 325

    Topics: Aprotinin; Bronchial Neoplasms; Electrolytes; Humans; Intestinal Neoplasms; Neoplasms; Pancreatic Ne

1969
A trial of thiethylperazine ("Torecan") in patients suffering from radiation sickness.
    The Medical journal of Australia, 1965, Aug-14, Volume: 2, Issue:7

    Topics: Dimenhydrinate; Feeding and Eating Disorders; Humans; Nausea; Neoplasms; Pyridoxine; Radiation Injur

1965
The tryptophan load as a test for pyridoxine deficiency in hospitalized patients.
    Annals of the New York Academy of Sciences, 1969, Sep-30, Volume: 166, Issue:1

    Topics: Adult; Aged; Arteriosclerosis; Female; Gastrointestinal Diseases; Humans; Kynurenine; Male; Middle A

1969
[Clinical trials of the combination: orthoxyquinoline sulfonate of aminophenazone-vitamin B 6- vitamin B 12 (Liocausyth) in rheumatological and neuritic diseases].
    Minerva medica, 1967, Mar-03, Volume: 58, Issue:18 Suppl

    Topics: Adult; Aged; Aminopyrine; Analgesics; Female; Humans; Male; Middle Aged; Neoplasms; Neuralgia; Neuri

1967
The manipulation of metabolism by drugs and nutrients.
    Cancer research, 1969, Volume: 29, Issue:12

    Topics: Antimetabolites; Asparaginase; Folic Acid Antagonists; Models, Chemical; Neoplasms; Nutritional Phys

1969
Clinical and biochemical studies of pyridoxine deficiency in patients with neoplastic diseases.
    Cancer, 1968, Volume: 21, Issue:5

    Topics: Adult; Aged; Aspartate Aminotransferases; Diet; Female; Humans; Leukocytes; Male; Middle Aged; Neopl

1968