pyridoxine has been researched along with Myoclonic Jerk in 11 studies
4,5-bis(hydroxymethyl)-2-methylpyridin-3-ol: structure in first source
vitamin B6 : Any member of the group of pyridines that exhibit biological activity against vitamin B6 deficiency. Vitamin B6 deficiency is associated with microcytic anemia, electroencephalographic abnormalities, dermatitis with cheilosis (scaling on the lips and cracks at the corners of the mouth) and glossitis (swollen tongue), depression and confusion, and weakened immune function. Vitamin B6 consists of the vitamers pyridoxine, pyridoxal, and pyridoxamine and their respective 5'-phosphate esters (and includes their corresponding ionized and salt forms).
| Excerpt | Relevance | Reference |
|---|---|---|
| "In mice, the ED(50) values for seizures following intraperitoneal injection were allylglycine 1." | 5.25 | Seizures induced by allylglycine, 3-mercaptopropionic acid and 4-deoxypyridoxine in mice and photosensitive baboons, and different modes of inhibition of cerebral glutamic acid decarboxylase. ( Horton, RW; Meldrum, BS, 1973) |
| "The clinical features included confusion and/or clouding of consciousness, marked oppositional hypertonus ('gegenhalten') and myoclonus." | 1.27 | The clinical spectrum of alcoholic pellagra encephalopathy. A retrospective analysis of 22 cases studied pathologically. ( Buge, A; Castaigne, P; Goulon, M; Hausser-Hauw, C; Hauw, JJ; Laplane, D; Lhermitte, F; Serdaru, M, 1988) |
| "In mice, the ED(50) values for seizures following intraperitoneal injection were allylglycine 1." | 1.25 | Seizures induced by allylglycine, 3-mercaptopropionic acid and 4-deoxypyridoxine in mice and photosensitive baboons, and different modes of inhibition of cerebral glutamic acid decarboxylase. ( Horton, RW; Meldrum, BS, 1973) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (90.91) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (9.09) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gospe, SM | 1 |
| FRENCH, JH | 1 |
| GRUETER, BB | 1 |
| DRUCKMAN, R | 1 |
| O'BRIEN, D | 1 |
| Serdaru, M | 1 |
| Hausser-Hauw, C | 1 |
| Laplane, D | 1 |
| Buge, A | 1 |
| Castaigne, P | 1 |
| Goulon, M | 1 |
| Lhermitte, F | 1 |
| Hauw, JJ | 1 |
| Meldrum, BS | 2 |
| Balzano, E | 1 |
| Gadea, M | 1 |
| Naquet, R | 1 |
| Rohmer, F | 1 |
| Warter, JM | 1 |
| Coquillat, G | 1 |
| Maitrot, D | 1 |
| Kurtz, D | 1 |
| Micheletti, G | 1 |
| Mack, G | 1 |
| Mandel, P | 1 |
| Horton, RW | 1 |
| Hartmann-von Monakow, K | 1 |
| Grossi-Bianchi, ML | 2 |
| Pistone, FM | 2 |
| Gandullia, E | 2 |
| Segni, G | 2 |
| Gallagher, BB | 2 |
| Smith, DB | 1 |
1 trial available for pyridoxine and Myoclonic Jerk
| Article | Year |
|---|---|
[Pharmacological and biochemical approach to a syndrome of action and intention myoclonus in the course of degenerative disease of the nervous system].
Topics: 5-Hydroxytryptophan; Adult; Benzazepines; Cerebellar Ataxia; Clinical Trials as Topic; Diagnosis, Di | 1973 |
10 other studies available for pyridoxine and Myoclonic Jerk
| Article | Year |
|---|---|
Pyridoxine-dependent epilepsy and pyridoxine phosphate oxidase deficiency: unique clinical symptoms and non-specific EEG characteristics.
Topics: Anticonvulsants; Brain; Brain Diseases, Metabolic; Electroencephalography; Epilepsy; Eye Movements; | 2010 |
PYRIDOXINE AND INFANTILE MYOCLONIC SEIZURES.
Topics: Amino Acids; Drug Therapy; Electroencephalography; Epilepsies, Myoclonic; Humans; Infant; Kynurenic | 1965 |
The clinical spectrum of alcoholic pellagra encephalopathy. A retrospective analysis of 22 cases studied pathologically.
Topics: Adult; Aged; Alcoholism; Cognition Disorders; Confusion; Consciousness Disorders; Female; Humans; Ma | 1988 |
Photic and drug-induced epilepsy in the baboon (Papio papio): the effects of isoniazid, thiosemicarbazide, pyridoxine and amino-oxyacetic acid.
Topics: Acetates; Aminobutyrates; Animals; Behavior, Animal; Cerebral Cortex; Electroencephalography; Haplor | 1970 |
Seizures induced by allylglycine, 3-mercaptopropionic acid and 4-deoxypyridoxine in mice and photosensitive baboons, and different modes of inhibition of cerebral glutamic acid decarboxylase.
Topics: Allyl Compounds; Animals; Brain; Carboxy-Lyases; Electroencephalography; Glutamates; Glycine; Haplor | 1973 |
[Specific therapy of extrapyramidal-motor syndromes].
Topics: Analgesics; Athetosis; Chorea; Datura stramonium; Dihydroxyphenylalanine; Dystonia Musculorum Deform | 1969 |
[Association of pyridoxine and ACTH in the treatment of infantile myoclonic encephalopathy with hypsarrhythmia].
Topics: Adrenocorticotropic Hormone; Brain Diseases; Humans; Infant; Myoclonus; Pyridoxine; Spasms, Infantil | 1966 |
[The role of pyridoxine in the pathogenesis and therapy of the spastic-hypsarrhythmia syndrome. Studies and considerations on 56 cases].
Topics: Adrenocorticotropic Hormone; Drug Synergism; Electroencephalography; Humans; Infant; Infant, Newborn | 1967 |
The influence of tyrosine, phenylpyruvate and vitamin B 6 upon seizure thresholds.
Topics: Amino Acids; Animals; Brain; Brain Chemistry; Central Nervous System Stimulants; Ethers; Fluorine; M | 1971 |
The effect of penicillamine on seizure threshold. The role of pyridoxine.
Topics: Animals; Disease Models, Animal; Male; Myoclonus; Penicillamine; Pyridoxine; Rats; Seizures; Tryptop | 1970 |