pyridoxine has been researched along with Multiple Sclerosis in 8 studies
4,5-bis(hydroxymethyl)-2-methylpyridin-3-ol: structure in first source
vitamin B6 : Any member of the group of pyridines that exhibit biological activity against vitamin B6 deficiency. Vitamin B6 deficiency is associated with microcytic anemia, electroencephalographic abnormalities, dermatitis with cheilosis (scaling on the lips and cracks at the corners of the mouth) and glossitis (swollen tongue), depression and confusion, and weakened immune function. Vitamin B6 consists of the vitamers pyridoxine, pyridoxal, and pyridoxamine and their respective 5'-phosphate esters (and includes their corresponding ionized and salt forms).
Multiple Sclerosis: An autoimmune disorder mainly affecting young adults and characterized by destruction of myelin in the central nervous system. Pathologic findings include multiple sharply demarcated areas of demyelination throughout the white matter of the central nervous system. Clinical manifestations include visual loss, extra-ocular movement disorders, paresthesias, loss of sensation, weakness, dysarthria, spasticity, ataxia, and bladder dysfunction. The usual pattern is one of recurrent attacks followed by partial recovery (see MULTIPLE SCLEROSIS, RELAPSING-REMITTING), but acute fulminating and chronic progressive forms (see MULTIPLE SCLEROSIS, CHRONIC PROGRESSIVE) also occur. (Adams et al., Principles of Neurology, 6th ed, p903)
| Excerpt | Relevance | Reference |
|---|---|---|
| "A pilot study of the effect of D-penicillamine in multiple sclerosis (MS) was undertaken because of D-penicillamine's activity against RNA neurotropic viruses, because it is effective against the auto-immune disease, rheumatoid arthritis, and because both viruses and autoimmunity have been implicated in multiple sclerosis." | 7.66 | Pilot study of d-penicillamine, vitamins and minerals in multiple sclerosis. ( Alba, A; Berger, AR; Rudez, A; Seelig, MS; Tarlau, M, 1978) |
| "A pilot study of the effect of D-penicillamine in multiple sclerosis (MS) was undertaken because of D-penicillamine's activity against RNA neurotropic viruses, because it is effective against the auto-immune disease, rheumatoid arthritis, and because both viruses and autoimmunity have been implicated in multiple sclerosis." | 3.66 | Pilot study of d-penicillamine, vitamins and minerals in multiple sclerosis. ( Alba, A; Berger, AR; Rudez, A; Seelig, MS; Tarlau, M, 1978) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (87.50) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (12.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Evans, E | 1 |
| Piccio, L | 1 |
| Cross, AH | 1 |
| PRITZSCHE, G | 1 |
| Seelig, MS | 1 |
| Alba, A | 1 |
| Berger, AR | 1 |
| Rudez, A | 1 |
| Tarlau, M | 1 |
| Husemann, F | 1 |
| Kugler, J | 1 |
| Frank, I | 1 |
| Schwarz, D | 1 |
| Mitchell, DA | 1 |
| Schandl, EK | 1 |
| Cook, DC | 1 |
| Lenský, P | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Adjuvant Effects of Vitamin A and Vitamin D Supplementation on Treatment of Children With ADHD:A Randomized, Double Blind, Placebo-controlled, Multicentric Trial.[NCT04284059] | Phase 4 | 504 participants (Anticipated) | Interventional | 2021-02-25 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for pyridoxine and Multiple Sclerosis
| Article | Year |
|---|---|
Use of Vitamins and Dietary Supplements by Patients With Multiple Sclerosis: A Review.
Topics: Acetylcarnitine; Animals; Ascorbic Acid; Biotin; Caffeine; Creatine; Curcumin; Dietary Supplements; | 2018 |
Carbon monoxide, vitamin B6, and multiple sclerosis: a theory of interrelationship.
Topics: Age Factors; Air Pollution; Animals; Automobiles; Carbon Monoxide; Climate; Diet Therapy; Dietary Fa | 1973 |
1 trial available for pyridoxine and Multiple Sclerosis
| Article | Year |
|---|---|
[Relaxation-promoting effect of vitamin B with anabolics].
Topics: Action Potentials; Adult; Anabolic Agents; Androstanes; Attention; Blood Pressure; Cerebral Hemorrha | 1970 |
5 other studies available for pyridoxine and Multiple Sclerosis
| Article | Year |
|---|---|
[On the treatment of inflammatory neurological diseases with a vitamin-enzyme combination].
Topics: Adenine Nucleotides; Herpes Zoster; Humans; Multiple Sclerosis; Nervous System Diseases; Neuralgia; | 1962 |
Pilot study of d-penicillamine, vitamins and minerals in multiple sclerosis.
Topics: Adult; Autoimmune Diseases; Brain; Dose-Response Relationship, Drug; Female; Humans; Magnesium; Male | 1978 |
[Microcirculatory therapy of multiple sclerosis].
Topics: Adult; Ascorbic Acid; Blood Circulation; Blood Coagulation; Diet Therapy; Female; Humans; Male; Midd | 1970 |
Letter: Environmental carbon monoxide and multiple sclerosis.
Topics: Air Pollution; Carbon Monoxide; Environmental Exposure; Humans; Multiple Sclerosis; Pyridoxine | 1974 |
[Emetine in the management of multiple sclerosis].
Topics: Adult; Emetine; Female; Humans; Male; Middle Aged; Multiple Sclerosis; Neurologic Examination; Pyrid | 1968 |