pyridoxine has been researched along with Metabolic Diseases in 36 studies
4,5-bis(hydroxymethyl)-2-methylpyridin-3-ol: structure in first source
vitamin B6 : Any member of the group of pyridines that exhibit biological activity against vitamin B6 deficiency. Vitamin B6 deficiency is associated with microcytic anemia, electroencephalographic abnormalities, dermatitis with cheilosis (scaling on the lips and cracks at the corners of the mouth) and glossitis (swollen tongue), depression and confusion, and weakened immune function. Vitamin B6 consists of the vitamers pyridoxine, pyridoxal, and pyridoxamine and their respective 5'-phosphate esters (and includes their corresponding ionized and salt forms).
Metabolic Diseases: Generic term for diseases caused by an abnormal metabolic process. It can be congenital due to inherited enzyme abnormality (METABOLISM, INBORN ERRORS) or acquired due to disease of an endocrine organ or failure of a metabolically important organ such as the liver. (Stedman, 26th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "We report intermittent seizures, lethargy, and Cohen's syndrome in a 4-year-old girl with hyper-beta-alaninemia and a partial deficiency of beta-alanyl-alpha-ketoglutarate transaminase (AKT)." | 7.69 | Pyridoxine-responsive hyper-beta-alaninemia associated with Cohen's syndrome. ( Barton, NW; Bernardini, I; Brady, RO; Higgins, JJ; Kaneski, CR, 1994) |
| " Antiquitin deficiency is the most common form of pyridoxine-dependent epilepsy." | 5.05 | Inherited Disorders of Lysine Metabolism: A Review. ( Bouchereau, J; Schiff, M, 2020) |
| "We report intermittent seizures, lethargy, and Cohen's syndrome in a 4-year-old girl with hyper-beta-alaninemia and a partial deficiency of beta-alanyl-alpha-ketoglutarate transaminase (AKT)." | 3.69 | Pyridoxine-responsive hyper-beta-alaninemia associated with Cohen's syndrome. ( Barton, NW; Bernardini, I; Brady, RO; Higgins, JJ; Kaneski, CR, 1994) |
| "Pyridoxine has been reported as having an antilactogenic effect, presumably by suppressing prolactin secretion." | 2.64 | Failure of pyridoxine to suppress raised serum prolactin levels. ( de Waal, JM; Harms, JH; Pannall, PR; Slabber, CF; Steyn, AF, 1978) |
| "About 7/18 (39%) of patients showed seizure-free with pyridoxine (PN) or pyridoxal-5'-phosphate treatment." | 1.91 | Analysis for variable manifestations and molecular characteristics of pyridox(am)ine-5'-phosphate oxidase (PNPO) deficiency. ( Gong, P; Jiao, X; Niu, Y; Xu, Z; Yang, Z; Zhang, Y, 2023) |
| " As vitamin C is a precursor of oxalate in patients on regular hemodialysis, we have measured plasma levels of vitamin C, oxalate, pyridoxine, thiamine and creatinine twice before and 4 weeks after a change of vitamin C dosage in 49 dialysis patients who had been receiving 500 mg of oral vitamin C daily for more than 6 months." | 1.27 | Secondary hyperoxalemia caused by vitamin C supplementation in regular hemodialysis patients. ( Ono, K, 1986) |
| " Cases of calciumoxalate urolithiasis have also been reported after chronic administration of piridoxilate." | 1.27 | [Acute renal failure caused by acute oxalosis after massive ingestion of pyridoxilate]. ( Benoit, O; Dequiedt, P; Dracon, M; Gosselin, B; Le Maguer, D; Lebleu, J; Lelièvre, G; MacNamara, E; Pagniez, D; Tacquet, A, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 31 (86.11) | 18.7374 |
| 1990's | 2 (5.56) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 3 (8.33) | 2.80 |
| Authors | Studies |
|---|---|
| Jiao, X | 1 |
| Gong, P | 1 |
| Niu, Y | 1 |
| Xu, Z | 1 |
| Zhang, Y | 1 |
| Yang, Z | 1 |
| Bouchereau, J | 1 |
| Schiff, M | 1 |
| Clayton, PT | 1 |
| BOGDANOVA, EV | 1 |
| RIEKE, JA | 1 |
| VERGA, G | 1 |
| BECKMANN, R | 1 |
| KOMROWER, GM | 1 |
| WILSON, V | 1 |
| CLAMP, JR | 1 |
| WESTALL, RG | 1 |
| MARIE, J | 1 |
| HENNEQUET, A | 1 |
| LYON, G | 1 |
| DEBRIS, P | 1 |
| LE BALLE, JC | 1 |
| Scheinman, JI | 1 |
| Najarian, JS | 1 |
| Mauer, SM | 1 |
| O'Regan, P | 1 |
| Constable, AR | 1 |
| Joekes, AM | 1 |
| Kasidas, GP | 1 |
| Rose, GA | 1 |
| Higgins, JJ | 1 |
| Kaneski, CR | 1 |
| Bernardini, I | 1 |
| Brady, RO | 1 |
| Barton, NW | 1 |
| Will, EJ | 1 |
| Bijvoet, OL | 1 |
| de Waal, JM | 1 |
| Steyn, AF | 1 |
| Harms, JH | 1 |
| Slabber, CF | 1 |
| Pannall, PR | 1 |
| Láhoda, F | 1 |
| Riva, E | 1 |
| Borzani, M | 1 |
| Motta, G | 1 |
| Giovannini, M | 1 |
| Bringmann, G | 1 |
| Feineis, D | 1 |
| Friedrich, H | 1 |
| Hille, A | 1 |
| Ono, K | 1 |
| Dequiedt, P | 1 |
| Gosselin, B | 1 |
| Benoit, O | 1 |
| Le Maguer, D | 1 |
| Lebleu, J | 1 |
| MacNamara, E | 1 |
| Pagniez, D | 1 |
| Dracon, M | 1 |
| Lelièvre, G | 1 |
| Tacquet, A | 1 |
| Tabolin, VA | 1 |
| Kruglov, BV | 1 |
| Lebedev, VP | 1 |
| Levitina, NO | 1 |
| Heinmets, F | 1 |
| Wilcken, B | 1 |
| Turner, B | 1 |
| Snodgrass, GJ | 1 |
| Gibbs, DA | 2 |
| Watts, RW | 2 |
| Easton, EJ | 1 |
| Simpson, I | 1 |
| Martin, JK | 1 |
| Campbell, M | 1 |
| Vibrans, U | 1 |
| Hilgenfeldt, J | 1 |
| Petres, J | 1 |
| Gaull, GE | 1 |
| Morrow, G | 1 |
| Barness, LA | 1 |
| Calandra, P | 1 |
| Lissitzky, S | 1 |
| Laurent, B | 1 |
| Bernard, P | 1 |
| Fenasse, R | 1 |
| Scriver, CR | 1 |
| Berariu, T | 1 |
| Băltescu, V | 1 |
| Proinov, I | 1 |
| Cătană, R | 1 |
| Heeley, AF | 1 |
| Roberts, GE | 1 |
5 reviews available for pyridoxine and Metabolic Diseases
| Article | Year |
|---|---|
Inherited Disorders of Lysine Metabolism: A Review.
Topics: 2-Aminoadipic Acid; Aldehyde Dehydrogenase; Amino Acid Metabolism, Inborn Errors; Arginine; Brain; B | 2020 |
[PYRIDOXINE IN THE PATHOGENESIS AND THERAPY OF NEUROLOGIC AND PSYCHIATRIC DISEASES].
Topics: Alcoholism; Brain Diseases; Chorea; Extrapyramidal Tracts; Genetics, Medical; Humans; Intellectual D | 1963 |
Endogenous alkaloids in man--synthesis, analytics, in vivo identification, and medicinal importance.
Topics: Alkaloids; Carbolines; Humans; Isoquinolines; Metabolic Diseases; Molecular Structure; Pyridoxine | 1991 |
[Chief clinical syndromes in children with tryptophan metabolism disorders (literature survey)].
Topics: Amino Acid Metabolism, Inborn Errors; Amino Acids; Carboxy-Lyases; Child; Child, Preschool; Diabetes | 1972 |
Oral contraceptive agents and vitamins.
Topics: Anemia, Macrocytic; Animals; Contraceptives, Oral; Estrogens; Female; Folic Acid; Glutamates; Humans | 1972 |
1 trial available for pyridoxine and Metabolic Diseases
| Article | Year |
|---|---|
Failure of pyridoxine to suppress raised serum prolactin levels.
Topics: Chlorpromazine; Female; Galactorrhea; Humans; Lactation; Metabolic Diseases; Pregnancy; Prolactin; P | 1978 |
30 other studies available for pyridoxine and Metabolic Diseases
| Article | Year |
|---|---|
Analysis for variable manifestations and molecular characteristics of pyridox(am)ine-5'-phosphate oxidase (PNPO) deficiency.
Topics: Brain Diseases, Metabolic; Humans; Hypoxia-Ischemia, Brain; Metabolic Diseases; Oxidoreductases; Pho | 2023 |
The effectiveness of correcting abnormal metabolic profiles.
Topics: 3-Hydroxysteroid Dehydrogenases; Administration, Oral; Bile Acids and Salts; Epilepsy; Humans; Metab | 2020 |
[Pyridoxine metabolism in normal humans and in patients with certain kidney diseases].
Topics: Humans; Kidney; Kidney Diseases; Metabolic Diseases; Pyridoxine; Vitamin B 6 | 1958 |
INHERITANCE OF GENE DIFFERENCES IN NEUROSPORA CRASSA.
Topics: Arginine; Culture Media; Heredity; Metabolic Diseases; Mutation; Neurospora; Neurospora crassa; Niac | 1963 |
[PATHOGENIC ELEMENTS AND THERAPEUTIC EXPERIENCES CONCERNING ERB'S PROGRESSIVE MUSCULAR DYSTROPHY].
Topics: Adenosine Triphosphate; Albumins; Ascorbic Acid; Calcium, Dietary; Choline; Diet; Diet Therapy; Frui | 1964 |
HYDROXYKYNURENINURIA: A CASE OF ABNORMAL TRYPTOPHAN METABOLISM PROBABLY DUE TO A DEFICIENCY OF KYNURENINASE.
Topics: Amino Acid Metabolism, Inborn Errors; Child; Chromatography; Electrophoresis; Humans; Hydrolases; Ky | 1964 |
[Pyridoxine-dependence, a metabolic disease manifested by pyridoxine-sensitive convulsive seizures. (First familial case)].
Topics: Child; Epilepsy; Humans; Infant; Metabolic Diseases; Pyridoxine; Seizures; Vitamin B 6 Deficiency | 1961 |
Successful strategies for renal transplantation in primary oxalosis.
Topics: Adult; Biopsy; Calcium Oxalate; Child; Child, Preschool; Diuretics; Female; Humans; Infant; Kidney; | 1984 |
Successful renal transplantation in primary hyperoxaluria.
Topics: Adult; Humans; Kidney Transplantation; Male; Metabolic Diseases; Oxalates; Pyridoxine | 1980 |
Pyridoxine-responsive hyper-beta-alaninemia associated with Cohen's syndrome.
Topics: 4-Aminobutyrate Transaminase; Abnormalities, Multiple; beta-Alanine; Child; Female; Humans; Intellec | 1994 |
Primary oxalosis: clinical and biochemical response to high-dose pyridoxine therapy.
Topics: Adult; Dose-Response Relationship, Drug; Female; Glyceric Acids; Glycolates; Humans; Metabolic Disea | 1979 |
[Disorders of methionine metabolism in polyneuropathies].
Topics: Adult; Alcoholism; Cystathionine; Diabetic Neuropathies; Female; Humans; Male; Metabolic Diseases; M | 1976 |
[Changes of serum ammonium in various pediatric diseases in relation to the treatment with anti-ammonemic drugs].
Topics: Ammonia; Arginine; Carboxylic Acids; Child, Preschool; Citrates; Female; Humans; Infant; Male; Metab | 1976 |
Secondary hyperoxalemia caused by vitamin C supplementation in regular hemodialysis patients.
Topics: Ascorbic Acid; Female; Humans; Male; Metabolic Diseases; Oxalates; Oxalic Acid; Pyridoxine; Renal Di | 1986 |
[Acute renal failure caused by acute oxalosis after massive ingestion of pyridoxilate].
Topics: Acute Kidney Injury; Adult; Humans; Kidney; Kidney Calculi; Male; Metabolic Diseases; Oxalates; Pyri | 1985 |
Biochemistry and pathology of tryptoPHAN METABOLISM AND ITS REGULATION BY AMINO ACIDS, vitamin B 6 and steroid hormones.
Topics: Amino Acids; Animals; Congresses as Topic; Feedback; Humans; Metabolic Diseases; Pyridoxine; Steroid | 1971 |
Computer simulation and analysis of tryptophan metabolism via kynurenine pathway in liver.
Topics: Coenzymes; Computers, Analog; Diagnosis, Computer-Assisted; Feedback; Humans; Kynurenic Acid; Kynure | 1974 |
Homocystinuria. Reduced folate levels during pyridoxine treatment.
Topics: Child; Child, Preschool; Cystine; Erythrocytes; Female; Folic Acid; Homocysteine; Homocystine; Homoc | 1973 |
Seizures in newborn infants.
Topics: Birth Injuries; Brain; Calcium; Diazepam; Gluconates; Glucose; Humans; Hypocalcemia; Hypoxia; Infant | 1974 |
Biochemical studies on the treatment of primary hyperoxaluria.
Topics: Adolescent; Allopurinol; Child; Dietary Proteins; Disulfiram; Enzyme Inhibitors; Female; Folic Acid; | 1967 |
Tyrosinemia induced by a pyridoxine antagonist, desoxypyridoxine.
Topics: Depression, Chemical; Female; In Vitro Techniques; Lactation; Liver; Liver Cirrhosis; Male; Metaboli | 1972 |
[Pyridoxal-5-phosphate in porphyria cutanea tarda].
Topics: Adult; Alanine Transaminase; Alkaline Phosphatase; Aspartate Aminotransferases; Copper; Female; Foll | 1972 |
Homocystinuria, vitamin B 6 , and folate: metabolic interrelationships and clinical significance.
Topics: Alcohol Oxidoreductases; Cystathionine; Folic Acid; Glycine; Homocystine; Homocystinuria; Humans; L- | 1972 |
Combined vitamin responsiveness in homocystinuria.
Topics: Adolescent; Adult; Amino Acids; Child; Drug Synergism; Female; Folic Acid; Folic Acid Deficiency; Gl | 1972 |
The action of pyridoxine in primary hyperoxaluria.
Topics: Adolescent; Adult; Child; Female; Humans; Kynurenic Acid; Kynurenine; Male; Metabolic Diseases; Mixe | 1970 |
[New viewpoints on the pathogenesis of pellagra].
Topics: Humans; Kynurenine; Metabolic Diseases; Pellagra; Pyridoxine; Riboflavin; Tryptophan | 1970 |
[Experimental studies in a case of tyrosinosis. New pathogenic hypothesis].
Topics: Adult; Amino Acids; Animals; Blood Glucose; Carbon Dioxide; Chromatography; Depression, Chemical; Di | 1969 |
Vitamin B 6 dependency syndromes: their larger significance.
Topics: Genetics; Humans; Metabolic Diseases; Pyridoxine | 1966 |
[Studies on disturbances of mineral metabolism in oxalurilithiasis and their adjustment].
Topics: Calcium; Citrates; Humans; Magnesium; Metabolic Diseases; Oxalates; Pyridoxine; Urinary Calculi | 1966 |
A study of tryptophan metabolism in psychotic children.
Topics: Autoradiography; Carbon Isotopes; Child; Child, Preschool; Female; Humans; Kynurenine; Male; Metabol | 1966 |