pyridoxine has been researched along with Liver Diseases, Alcoholic in 9 studies
4,5-bis(hydroxymethyl)-2-methylpyridin-3-ol: structure in first source
vitamin B6 : Any member of the group of pyridines that exhibit biological activity against vitamin B6 deficiency. Vitamin B6 deficiency is associated with microcytic anemia, electroencephalographic abnormalities, dermatitis with cheilosis (scaling on the lips and cracks at the corners of the mouth) and glossitis (swollen tongue), depression and confusion, and weakened immune function. Vitamin B6 consists of the vitamers pyridoxine, pyridoxal, and pyridoxamine and their respective 5'-phosphate esters (and includes their corresponding ionized and salt forms).
Liver Diseases, Alcoholic: Liver diseases associated with ALCOHOLISM. It usually refers to the coexistence of two or more subentities, i.e., ALCOHOLIC FATTY LIVER; ALCOHOLIC HEPATITIS; and ALCOHOLIC CIRRHOSIS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The paper aims to evaluate the effects of metadoxine on liver function tests in chronic alcohol abusers without a clear alcohol dependence, by means of an open trial carried out in 7 hospitals in Tuscany." | 9.07 | [Effects of metadoxine on main biohumoral changes induced by chronic alcoholism]. ( Corsini, G; Gelso, E; Giuliano, G, 1992) |
| "The paper aims to evaluate the effects of metadoxine on liver function tests in chronic alcohol abusers without a clear alcohol dependence, by means of an open trial carried out in 7 hospitals in Tuscany." | 5.07 | [Effects of metadoxine on main biohumoral changes induced by chronic alcoholism]. ( Corsini, G; Gelso, E; Giuliano, G, 1992) |
| "Metadoxine is an active drug for treatment of acute and chronic alcohol intoxication, affecting both liver and brain function." | 1.28 | [Metadoxine in alcohol-related pathology]. ( Camarri, F; Corradini, P; Santoni, S; Zocchi, M, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (44.44) | 18.7374 |
| 1990's | 1 (11.11) | 18.2507 |
| 2000's | 2 (22.22) | 29.6817 |
| 2010's | 2 (22.22) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Mao, YM | 1 |
| Zeng, MD | 1 |
| Li, YM | 1 |
| Wang, BY | 1 |
| Shang, J | 1 |
| Shi, RH | 1 |
| Liu, JY | 1 |
| Lu, LG | 1 |
| Cao, AP | 1 |
| Leggio, L | 1 |
| Kenna, GA | 1 |
| Ferrulli, A | 1 |
| Zywiak, WH | 1 |
| Caputo, F | 1 |
| Swift, RM | 1 |
| Addolorato, G | 1 |
| Sil'vestrova, SIu | 1 |
| Fedotova, SIu | 1 |
| Drozdov, TF | 1 |
| Petrakov, AV | 1 |
| Bonjour, JP | 1 |
| Jacobs, RM | 1 |
| Sorrell, MF | 1 |
| Pár, A | 1 |
| Baker, H | 1 |
| Frank, O | 1 |
| Zetterman, RK | 1 |
| Rajan, KS | 1 |
| ten Hove, W | 1 |
| Leevy, CM | 1 |
| Corsini, G | 1 |
| Gelso, E | 1 |
| Giuliano, G | 1 |
| Santoni, S | 1 |
| Corradini, P | 1 |
| Zocchi, M | 1 |
| Camarri, F | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Novel Pharmacotherapy for Alcoholism and Alcohol Liver Disease[NCT01504295] | Phase 2 | 38 participants (Actual) | Interventional | 2012-04-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 reviews available for pyridoxine and Liver Diseases, Alcoholic
| Article | Year |
|---|---|
Vitamins and alcoholism. III. Vitamin B6.
Topics: Alcoholism; Anemia, Sideroblastic; Animals; Aspartate Aminotransferases; False Positive Reactions; F | 1980 |
The role of nutrition in the pathogenesis of alcoholic liver disease.
Topics: Alcoholic Beverages; Animals; Carbohydrates; Diet; Energy Intake; Ethanol; Folic Acid; Humans; Intes | 1981 |
[Treatment of alcoholic liver diseases. Abstinence, nutritional support, drug therapy, liver transplantation].
Topics: Alcohol Deterrents; Antioxidants; Drug Combinations; Fatty Liver, Alcoholic; Hormones; Humans; Liver | 2000 |
2 trials available for pyridoxine and Liver Diseases, Alcoholic
| Article | Year |
|---|---|
[Capsule metadoxine in the treatment of alcoholic liver disease: a randomized, double-blind, placebo-controlled, multicenter study].
Topics: Administration, Oral; Adult; Aged; Alanine Transaminase; Alcohol Deterrents; Analysis of Variance; A | 2009 |
[Effects of metadoxine on main biohumoral changes induced by chronic alcoholism].
Topics: Adult; Aged; Alcoholism; Drug Combinations; Female; Humans; Liver; Liver Diseases, Alcoholic; Liver | 1992 |
4 other studies available for pyridoxine and Liver Diseases, Alcoholic
| Article | Year |
|---|---|
Preliminary findings on the use of metadoxine for the treatment of alcohol dependence and alcoholic liver disease.
Topics: Adult; Alcohol Deterrents; Alcoholism; Dose-Response Relationship, Drug; Drug Combinations; Female; | 2011 |
[Dynamics of antipirin test at patients with alcoholic liver disease on the background of metadoksin drug receiving].
Topics: Adult; Alcohol Deterrents; Anti-Inflammatory Agents, Non-Steroidal; Antipyrine; Drug Combinations; F | 2011 |
Inability of chronic alcoholics with liver disease to use food as a source of folates, thiamin and vitamin B6.
Topics: Adult; Female; Folic Acid; Folic Acid Deficiency; Humans; Intestinal Absorption; Liver Diseases, Alc | 1975 |
[Metadoxine in alcohol-related pathology].
Topics: Adult; Aged; Drug Combinations; Female; Humans; Liver Diseases, Alcoholic; Male; Middle Aged; Pyrido | 1989 |