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pyridoxine and Leukemia, Myelogenous, Chronic, BCR-ABL Positive

pyridoxine has been researched along with Leukemia, Myelogenous, Chronic, BCR-ABL Positive in 1 studies

4,5-bis(hydroxymethyl)-2-methylpyridin-3-ol: structure in first source
vitamin B6 : Any member of the group of pyridines that exhibit biological activity against vitamin B6 deficiency. Vitamin B6 deficiency is associated with microcytic anemia, electroencephalographic abnormalities, dermatitis with cheilosis (scaling on the lips and cracks at the corners of the mouth) and glossitis (swollen tongue), depression and confusion, and weakened immune function. Vitamin B6 consists of the vitamers pyridoxine, pyridoxal, and pyridoxamine and their respective 5'-phosphate esters (and includes their corresponding ionized and salt forms).

Leukemia, Myelogenous, Chronic, BCR-ABL Positive: Clonal hematopoetic disorder caused by an acquired genetic defect in PLURIPOTENT STEM CELLS. It starts in MYELOID CELLS of the bone marrow, invades the blood and then other organs. The condition progresses from a stable, more indolent, chronic phase (LEUKEMIA, MYELOID, CHRONIC PHASE) lasting up to 7 years, to an advanced phase composed of an accelerated phase (LEUKEMIA, MYELOID, ACCELERATED PHASE) and BLAST CRISIS.

Research Excerpts

ExcerptRelevanceReference
"Progression in chronic myeloid leukemia (CML) was initially thought to be due to mutations."1.30Prevention of progression in chronic myeloid leukemia by altering DNA methylation with a pyridoxine analogue. ( Sastry, PS, 1999)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Sastry, PS1

Other Studies

1 other study available for pyridoxine and Leukemia, Myelogenous, Chronic, BCR-ABL Positive

ArticleYear
Prevention of progression in chronic myeloid leukemia by altering DNA methylation with a pyridoxine analogue.
    Medical hypotheses, 1999, Volume: 53, Issue:6

    Topics: DNA Methylation; DNA, Neoplasm; Humans; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Models, Bi

1999