pyridoxine has been researched along with Inflammation in 14 studies
4,5-bis(hydroxymethyl)-2-methylpyridin-3-ol: structure in first source
vitamin B6 : Any member of the group of pyridines that exhibit biological activity against vitamin B6 deficiency. Vitamin B6 deficiency is associated with microcytic anemia, electroencephalographic abnormalities, dermatitis with cheilosis (scaling on the lips and cracks at the corners of the mouth) and glossitis (swollen tongue), depression and confusion, and weakened immune function. Vitamin B6 consists of the vitamers pyridoxine, pyridoxal, and pyridoxamine and their respective 5'-phosphate esters (and includes their corresponding ionized and salt forms).
Inflammation: A pathological process characterized by injury or destruction of tissues caused by a variety of cytologic and chemical reactions. It is usually manifested by typical signs of pain, heat, redness, swelling, and loss of function.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Epidemiological and laboratory studies suggest that increasing concentrations of plasma homocysteine (total homocysteine [tHcy]) accelerate cardiovascular disease by promoting vascular inflammation, endothelial dysfunction, and hypercoagulability." | 9.11 | Homocysteine-lowering treatment with folic acid, cobalamin, and pyridoxine does not reduce blood markers of inflammation, endothelial dysfunction, or hypercoagulability in patients with previous transient ischemic attack or stroke: a randomized substudy o ( Baker, R; Dusitanond, P; Eikelboom, JW; Gilmore, G; Hankey, GJ; Jamrozik, K; Klijn, CJ; Langton, P; Loh, K; Thom, J; van Bockxmeer, FM; Yi, Q, 2005) |
| "A negative association between systemic markers of inflammation and plasma vitamin B-6 has been observed in population-based and patient cohorts; however, vitamin B-6 (pyridoxine) treatment has mostly failed to improve inflammatory indexes." | 7.78 | Association of plasma B-6 vitamers with systemic markers of inflammation before and after pyridoxine treatment in patients with stable angina pectoris. ( Midttun, Ø; Nygård, O; Pedersen, ER; Ueland, PM; Ulvik, A, 2012) |
| " Chronic inflammation induced by dorsal injections of 200 microliters of a 1:40 saturated crystal solution of potassium permanganate (KMnO4) in mice treated or untreated with 4-DPD (400 micrograms/dose), has been investigated." | 7.69 | 4-Deoxypyridoxine inhibits chronic granuloma formation induced by potassium permanganate in vivo. ( Conti, P; Dotsika, E; Fridas, S; Himonas, C; Karagouni, E; Trakatellis, A, 1994) |
| "Patients with rheumatoid arthritis have subnormal vitamin B6 status, both quantitatively and functionally." | 6.71 | Pyridoxine supplementation corrects vitamin B6 deficiency but does not improve inflammation in patients with rheumatoid arthritis. ( Bagley, PJ; Chiang, EP; Dallal, G; Roubenoff, R; Selhub, J, 2005) |
| "0001) number of patients demonstrated improvement over their previous acne treatment regimens after both 4 and 8 weeks of NicAzel (nicotinamide, azelaic acid, zinc, pyridoxine, copper, folic acid; Elorac Inc, Vernon Hills, IL) use." | 5.16 | Inflammatory acne management with a novel prescription dietary supplement. ( Akhavan, A; Day, D; Falcon, R; Iannotta, P; Janiga, A; Kallal, JE; Olansky, A; Shalita, AR; Singri, P, 2012) |
| "Epidemiological and laboratory studies suggest that increasing concentrations of plasma homocysteine (total homocysteine [tHcy]) accelerate cardiovascular disease by promoting vascular inflammation, endothelial dysfunction, and hypercoagulability." | 5.11 | Homocysteine-lowering treatment with folic acid, cobalamin, and pyridoxine does not reduce blood markers of inflammation, endothelial dysfunction, or hypercoagulability in patients with previous transient ischemic attack or stroke: a randomized substudy o ( Baker, R; Dusitanond, P; Eikelboom, JW; Gilmore, G; Hankey, GJ; Jamrozik, K; Klijn, CJ; Langton, P; Loh, K; Thom, J; van Bockxmeer, FM; Yi, Q, 2005) |
| "A negative association between systemic markers of inflammation and plasma vitamin B-6 has been observed in population-based and patient cohorts; however, vitamin B-6 (pyridoxine) treatment has mostly failed to improve inflammatory indexes." | 3.78 | Association of plasma B-6 vitamers with systemic markers of inflammation before and after pyridoxine treatment in patients with stable angina pectoris. ( Midttun, Ø; Nygård, O; Pedersen, ER; Ueland, PM; Ulvik, A, 2012) |
| " Chronic inflammation induced by dorsal injections of 200 microliters of a 1:40 saturated crystal solution of potassium permanganate (KMnO4) in mice treated or untreated with 4-DPD (400 micrograms/dose), has been investigated." | 3.69 | 4-Deoxypyridoxine inhibits chronic granuloma formation induced by potassium permanganate in vivo. ( Conti, P; Dotsika, E; Fridas, S; Himonas, C; Karagouni, E; Trakatellis, A, 1994) |
| "Pyridoxine deficiency and 4'-deoxypyridoxine produce acrodynia in rats and seborrheic dermatitis in man." | 3.67 | Pyridoxine deficiency and antagonism produce increased ground substance viscosity with resulting seborrheic dermatitis and increased tumor resistance. ( Stone, OJ, 1989) |
| "Patients with rheumatoid arthritis have subnormal vitamin B6 status, both quantitatively and functionally." | 2.71 | Pyridoxine supplementation corrects vitamin B6 deficiency but does not improve inflammation in patients with rheumatoid arthritis. ( Bagley, PJ; Chiang, EP; Dallal, G; Roubenoff, R; Selhub, J, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (35.71) | 18.7374 |
| 1990's | 1 (7.14) | 18.2507 |
| 2000's | 6 (42.86) | 29.6817 |
| 2010's | 2 (14.29) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| WINTROBE, MM | 1 |
| GREENBERG, GR | 1 |
| Ulvik, A | 1 |
| Midttun, Ø | 1 |
| Pedersen, ER | 1 |
| Nygård, O | 1 |
| Ueland, PM | 1 |
| Shalita, AR | 1 |
| Falcon, R | 1 |
| Olansky, A | 1 |
| Iannotta, P | 1 |
| Akhavan, A | 1 |
| Day, D | 1 |
| Janiga, A | 1 |
| Singri, P | 1 |
| Kallal, JE | 1 |
| Dusitanond, P | 1 |
| Eikelboom, JW | 1 |
| Hankey, GJ | 1 |
| Thom, J | 1 |
| Gilmore, G | 1 |
| Loh, K | 1 |
| Yi, Q | 1 |
| Klijn, CJ | 1 |
| Langton, P | 1 |
| van Bockxmeer, FM | 1 |
| Baker, R | 1 |
| Jamrozik, K | 1 |
| Jonasson, T | 1 |
| Ohlin, AK | 1 |
| Gottsäter, A | 1 |
| Hultberg, B | 1 |
| Ohlin, H | 1 |
| Chiang, EP | 1 |
| Selhub, J | 2 |
| Bagley, PJ | 1 |
| Dallal, G | 1 |
| Roubenoff, R | 1 |
| Meacock, SC | 1 |
| Swann, BP | 1 |
| Dawson, W | 1 |
| Fridas, S | 1 |
| Trakatellis, A | 1 |
| Karagouni, E | 1 |
| Dotsika, E | 1 |
| Himonas, C | 1 |
| Conti, P | 1 |
| Daumer, KM | 1 |
| Khan, AU | 1 |
| Steinbeck, MJ | 1 |
| McCarty, MF | 1 |
| Friso, S | 1 |
| Jacques, PF | 1 |
| Wilson, PW | 1 |
| Rosenberg, IH | 1 |
| Stone, OJ | 2 |
| Chukichev, EM | 1 |
| Willis, CJ | 1 |
1 review available for pyridoxine and Inflammation
| Article | Year |
|---|---|
The dynamics and possible roles of metal complexes in inflammation.
Topics: Chemotaxis; Collagen; Copper; Humans; Immunity; In Vitro Techniques; Inflammation; Iron; Manganese; | 1981 |
4 trials available for pyridoxine and Inflammation
| Article | Year |
|---|---|
Inflammatory acne management with a novel prescription dietary supplement.
Topics: Acne Vulgaris; Adolescent; Adult; Anti-Bacterial Agents; Child; Copper; Dicarboxylic Acids; Dietary | 2012 |
Homocysteine-lowering treatment with folic acid, cobalamin, and pyridoxine does not reduce blood markers of inflammation, endothelial dysfunction, or hypercoagulability in patients with previous transient ischemic attack or stroke: a randomized substudy o
Topics: Biomarkers; Blood Coagulation; Cardiovascular Diseases; Endothelium, Vascular; Folic Acid; Homocyste | 2005 |
Plasma homocysteine and markers for oxidative stress and inflammation in patients with coronary artery disease--a prospective randomized study of vitamin supplementation.
Topics: Aged; Biomarkers; Coronary Artery Disease; Female; Folic Acid; Homocysteine; Humans; Hyperhomocystei | 2005 |
Pyridoxine supplementation corrects vitamin B6 deficiency but does not improve inflammation in patients with rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; Double-Blind Method; Female; Health Status; Humans; Inflammation; Male; Middl | 2005 |
9 other studies available for pyridoxine and Inflammation
| Article | Year |
|---|---|
The anemia of infection the uptake of radioactive iron in iron-deficient and in pyridoxine-deficient pigs before and after acute inflammation.
Topics: Anemia; Animals; Infections; Inflammation; Iron; Pyridoxine; Sus scrofa; Swine | 1947 |
Association of plasma B-6 vitamers with systemic markers of inflammation before and after pyridoxine treatment in patients with stable angina pectoris.
Topics: Aged; Angina, Stable; Biomarkers; C-Reactive Protein; Cross-Sectional Studies; Dietary Supplements; | 2012 |
4-Deoxypyridoxine inhibits chronic granuloma formation induced by potassium permanganate in vivo.
Topics: Animals; Granuloma; Inflammation; Interleukin-6; Lymphocytes; Mice; Potassium Permanganate; Pyridoxi | 1994 |
Chlorination of pyridinium compounds. Possible role of hypochlorite, N-chloramines, and chlorine in the oxidation of pyridinoline cross-links of articular cartilage collagen type II during acute inflammation.
Topics: Cartilage, Articular; Chlorine; Collagen; Humans; Inflammation; Oxidation-Reduction; Pyridoxamine; P | 2000 |
Increased homocyst(e)ine associated with smoking, chronic inflammation, and aging may reflect acute-phase induction of pyridoxal phosphatase activity.
Topics: Acute-Phase Reaction; Aged; Aging; Chronic Disease; Coffee; Enzyme Induction; Homocysteine; Homocyst | 2000 |
Low circulating vitamin B(6) is associated with elevation of the inflammation marker C-reactive protein independently of plasma homocysteine levels.
Topics: Aged; Aged, 80 and over; C-Reactive Protein; Cohort Studies; Creatinine; Diet; Female; Folic Acid; H | 2001 |
Pyridoxine deficiency and antagonism produce increased ground substance viscosity with resulting seborrheic dermatitis and increased tumor resistance.
Topics: Acrodynia; Animals; Dermatitis, Seborrheic; Humans; Inflammation; Models, Biological; Neoplasms; Pyr | 1989 |
[Combined action of penicillin, levomycetin and some water-soluble vitamins on aseptic inflammation and phagocytosis].
Topics: Animals; Ascorbic Acid; Chloramphenicol; Drug Synergism; Female; Folic Acid; Inflammation; Male; Nia | 1966 |
Chloroquine enhancement of inflammation.
Topics: Animals; Chloroquine; Dimethyl Sulfoxide; Inflammation; Phosphates; Pyridoxine; Rabbits; Skin | 1968 |