pyridoxine has been researched along with Hypoglycemia in 9 studies
4,5-bis(hydroxymethyl)-2-methylpyridin-3-ol: structure in first source
vitamin B6 : Any member of the group of pyridines that exhibit biological activity against vitamin B6 deficiency. Vitamin B6 deficiency is associated with microcytic anemia, electroencephalographic abnormalities, dermatitis with cheilosis (scaling on the lips and cracks at the corners of the mouth) and glossitis (swollen tongue), depression and confusion, and weakened immune function. Vitamin B6 consists of the vitamers pyridoxine, pyridoxal, and pyridoxamine and their respective 5'-phosphate esters (and includes their corresponding ionized and salt forms).
Hypoglycemia: A syndrome of abnormally low BLOOD GLUCOSE level. Clinical hypoglycemia has diverse etiologies. Severe hypoglycemia eventually lead to glucose deprivation of the CENTRAL NERVOUS SYSTEM resulting in HUNGER; SWEATING; PARESTHESIA; impaired mental function; SEIZURES; COMA; and even DEATH.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Pyridoxine-dependent epilepsy (PDE) was first described in 1954." | 7.78 | Profound neonatal hypoglycemia and lactic acidosis caused by pyridoxine-dependent epilepsy. ( Connolly, MB; Coulter-Mackie, M; Horvath, GA; Jakobs, C; Mercimek-Mahmutoglu, S; Nelson, T; Sargent, M; Stockler-Ipsiroglu, S; Struys, E; Waters, PJ, 2012) |
| " Disruptions of glutamate metabolism have been implicated in other clinical disorders, such as pyridoxine-dependent seizures, confirming the importance of intact glutamate metabolism." | 4.81 | Disorders of glutamate metabolism. ( Kelly, A; Stanley, CA, 2001) |
| "Pyridoxine-dependent epilepsy (PDE) was first described in 1954." | 3.78 | Profound neonatal hypoglycemia and lactic acidosis caused by pyridoxine-dependent epilepsy. ( Connolly, MB; Coulter-Mackie, M; Horvath, GA; Jakobs, C; Mercimek-Mahmutoglu, S; Nelson, T; Sargent, M; Stockler-Ipsiroglu, S; Struys, E; Waters, PJ, 2012) |
| "Neonatal seizures, as distinguished from nonconvulsive abnormal movements, are a significant problem in neonatal intensive care units." | 2.37 | Neonatal seizures. ( Bergman, I; Crumrine, P; Painter, MJ, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (66.67) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (11.11) | 29.6817 |
| 2010's | 2 (22.22) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Orlov, MY | 1 |
| Mercimek-Mahmutoglu, S | 1 |
| Horvath, GA | 1 |
| Coulter-Mackie, M | 1 |
| Nelson, T | 1 |
| Waters, PJ | 1 |
| Sargent, M | 1 |
| Struys, E | 1 |
| Jakobs, C | 1 |
| Stockler-Ipsiroglu, S | 1 |
| Connolly, MB | 1 |
| Kelly, A | 1 |
| Stanley, CA | 1 |
| Strickler, RC | 1 |
| Painter, MJ | 1 |
| Bergman, I | 1 |
| Crumrine, P | 1 |
| Yaryura-Tobias, JA | 1 |
| Carson, NA | 1 |
| Saad, SF | 1 |
| Keuth, U | 1 |
3 reviews available for pyridoxine and Hypoglycemia
| Article | Year |
|---|---|
Disorders of glutamate metabolism.
Topics: Acetyltransferases; Amino-Acid N-Acetyltransferase; ATP-Binding Cassette Transporters; Bacterial Pro | 2001 |
Endocrine hypotheses for the etiology of premenstrual syndrome.
Topics: Endocrine Glands; Endorphins; Estrogens; Female; Humans; Hypoglycemia; Neurotransmitter Agents; Ovar | 1987 |
Neonatal seizures.
Topics: Adrenoleukodystrophy; Amino Acid Metabolism, Inborn Errors; Ammonia; Anesthetics, Local; Anticonvuls | 1986 |
6 other studies available for pyridoxine and Hypoglycemia
| Article | Year |
|---|---|
[TREATMENT OF A NEWBORN BABIES FOR AN ACUTE DISORDER OF THE BRAIN BLOOD CIRCULATION OF A HEMORRHAGIC TYPE].
Topics: Acute Disease; Anticonvulsants; Brain; Cerebrovascular Circulation; Female; Fluid Therapy; Hematoma; | 2015 |
Profound neonatal hypoglycemia and lactic acidosis caused by pyridoxine-dependent epilepsy.
Topics: 2-Aminoadipic Acid; Acidosis, Lactic; Aldehyde Dehydrogenase; Alleles; Anticonvulsants; Brain; Diffu | 2012 |
Behavioral-gluco-dysrhythmic triad.
Topics: Brain; Diet Therapy; Electroencephalography; Glucose Tolerance Test; Humans; Hypoglycemia; Phenytoin | 1973 |
Chemical pathology of amino acid diseases.
Topics: Adolescent; Adult; Amino Acid Metabolism, Inborn Errors; Chemical Phenomena; Chemistry; Child; Child | 1968 |
Further observations on the role of -aminobutyric acid in insulin-induced hypoglycaemic convulsions.
Topics: Acetates; Amino Acids; Aminobutyrates; Animals; Anticonvulsants; Blood Glucose; Brain; Brain Chemist | 1972 |
[Seizures in newborn infants].
Topics: Birth Injuries; Cerebral Hemorrhage; Diazepam; Female; Glucose; Humans; Hypernatremia; Hypoglycemia; | 1969 |