pyridoxine has been researched along with Hepatitis, Alcoholic in 4 studies
4,5-bis(hydroxymethyl)-2-methylpyridin-3-ol: structure in first source
vitamin B6 : Any member of the group of pyridines that exhibit biological activity against vitamin B6 deficiency. Vitamin B6 deficiency is associated with microcytic anemia, electroencephalographic abnormalities, dermatitis with cheilosis (scaling on the lips and cracks at the corners of the mouth) and glossitis (swollen tongue), depression and confusion, and weakened immune function. Vitamin B6 consists of the vitamers pyridoxine, pyridoxal, and pyridoxamine and their respective 5'-phosphate esters (and includes their corresponding ionized and salt forms).
Hepatitis, Alcoholic: INFLAMMATION of the LIVER due to ALCOHOL ABUSE. It is characterized by NECROSIS of HEPATOCYTES, infiltration by NEUTROPHILS, and deposit of MALLORY BODIES. Depending on its severity, the inflammatory lesion may be reversible or progress to LIVER CIRRHOSIS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To evaluate the impact of metadoxine (MTD) on the 3- and 6-mo survival of patients with severe alcoholic hepatitis (AH)." | 9.20 | Metadoxine improves the three- and six-month survival rates in patients with severe alcoholic hepatitis. ( Abdo-Francis, JM; Cruz-Herrera, J; Higuera-de la Tijera, F; Pérez-Hernández, JL; Pérez-Torres, E; Salas-Gordillo, F; Serralde-Zúñiga, AE; Servín-Caamaño, AI, 2015) |
| "The therapeutic effect of metadoxine on alcoholic and non-alcoholic steatohepatitis." | 8.82 | [The therapeutic effect of metadoxine on alcoholic and non-alcoholic steatohepatitis]. ( Blázovics, A; Fehér, J; Váli, L, 2005) |
| "To evaluate the impact of metadoxine (MTD) on the 3- and 6-mo survival of patients with severe alcoholic hepatitis (AH)." | 5.20 | Metadoxine improves the three- and six-month survival rates in patients with severe alcoholic hepatitis. ( Abdo-Francis, JM; Cruz-Herrera, J; Higuera-de la Tijera, F; Pérez-Hernández, JL; Pérez-Torres, E; Salas-Gordillo, F; Serralde-Zúñiga, AE; Servín-Caamaño, AI, 2015) |
| "The therapeutic effect of metadoxine on alcoholic and non-alcoholic steatohepatitis." | 4.82 | [The therapeutic effect of metadoxine on alcoholic and non-alcoholic steatohepatitis]. ( Blázovics, A; Fehér, J; Váli, L, 2005) |
| "The relationship between pyridoxal phosphate deficiency and activities of serum and liver aminotransferases was studied in 12 patients with alcoholic hepatitis." | 3.67 | Relationship between pyridoxal 5'-phosphate deficiency and aminotransferase levels in alcoholic hepatitis. ( Boitnott, J; Diehl, AM; Herlong, HF; Mezey, E; Potter, J; Van Duyn, MA, 1984) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (50.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Higuera-de la Tijera, F | 1 |
| Servín-Caamaño, AI | 1 |
| Serralde-Zúñiga, AE | 1 |
| Cruz-Herrera, J | 1 |
| Pérez-Torres, E | 1 |
| Abdo-Francis, JM | 1 |
| Salas-Gordillo, F | 1 |
| Pérez-Hernández, JL | 1 |
| Váli, L | 1 |
| Blázovics, A | 1 |
| Fehér, J | 1 |
| Diehl, AM | 1 |
| Potter, J | 1 |
| Boitnott, J | 1 |
| Van Duyn, MA | 1 |
| Herlong, HF | 1 |
| Mezey, E | 1 |
| Nami, R | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effect of Omega-5 Fatty Acid Supplement on Markers of Inflammation and Oxidative Stress in Patients With Severe Alcoholic Hepatitis Treated With Prednisone[NCT03732586] | 40 participants (Actual) | Interventional | 2018-09-30 | Completed | |||
| Impact of Metadoxine in the Oxidative Stress and Early Mortality in Patients With Severe Alcoholic Hepatitis[NCT02161653] | Phase 4 | 135 participants (Actual) | Interventional | 2010-04-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for pyridoxine and Hepatitis, Alcoholic
| Article | Year |
|---|---|
[The therapeutic effect of metadoxine on alcoholic and non-alcoholic steatohepatitis].
Topics: Alcohol Deterrents; Alcoholic Intoxication; Alcoholism; Drug Combinations; Fatty Liver; Fatty Liver, | 2005 |
1 trial available for pyridoxine and Hepatitis, Alcoholic
| Article | Year |
|---|---|
Metadoxine improves the three- and six-month survival rates in patients with severe alcoholic hepatitis.
Topics: Adult; Alcohol Abstinence; Alcohol Deterrents; Drug Administration Schedule; Drug Combinations; Drug | 2015 |
Metadoxine improves the three- and six-month survival rates in patients with severe alcoholic hepatitis.
Topics: Adult; Alcohol Abstinence; Alcohol Deterrents; Drug Administration Schedule; Drug Combinations; Drug | 2015 |
Metadoxine improves the three- and six-month survival rates in patients with severe alcoholic hepatitis.
Topics: Adult; Alcohol Abstinence; Alcohol Deterrents; Drug Administration Schedule; Drug Combinations; Drug | 2015 |
Metadoxine improves the three- and six-month survival rates in patients with severe alcoholic hepatitis.
Topics: Adult; Alcohol Abstinence; Alcohol Deterrents; Drug Administration Schedule; Drug Combinations; Drug | 2015 |
2 other studies available for pyridoxine and Hepatitis, Alcoholic
| Article | Year |
|---|---|
Relationship between pyridoxal 5'-phosphate deficiency and aminotransferase levels in alcoholic hepatitis.
Topics: Acute Disease; Adult; Alanine Transaminase; Aspartate Aminotransferases; Female; Hepatitis, Alcoholi | 1984 |
[Hepatic damage caused by drugs and evaluation of the therapeutic effectiveness of pyridoxine pyrrolidone carboxylate].
Topics: Adult; Aged; Chemical and Drug Induced Liver Injury; Female; Hepatitis, Alcoholic; Humans; Liver Dis | 1979 |