pyridoxine has been researched along with Heart Defects, Congenital in 11 studies
4,5-bis(hydroxymethyl)-2-methylpyridin-3-ol: structure in first source
vitamin B6 : Any member of the group of pyridines that exhibit biological activity against vitamin B6 deficiency. Vitamin B6 deficiency is associated with microcytic anemia, electroencephalographic abnormalities, dermatitis with cheilosis (scaling on the lips and cracks at the corners of the mouth) and glossitis (swollen tongue), depression and confusion, and weakened immune function. Vitamin B6 consists of the vitamers pyridoxine, pyridoxal, and pyridoxamine and their respective 5'-phosphate esters (and includes their corresponding ionized and salt forms).
Heart Defects, Congenital: Developmental abnormalities involving structures of the heart. These defects are present at birth but may be discovered later in life.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Case infants (n = 998) had nonsyndromic congenital heart defects and control infants (n = 3,029) had no congenital defects." | 1.30 | Nausea during pregnancy and congenital heart defects: a population-based case-control study. ( Boneva, RS; Botto, L; Erickson, JD; Moore, CA; Wong, LY, 1999) |
| "One of twins was born with prune belly syndrome and congenital heart defect following exposure to Bendectin and Tigan." | 1.27 | Prune belly syndrome and heart defect in one of monozygotic twins, following exposure to Tigan and Bendectin. ( Greene, C; Shapira, E; Wilson, A, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (81.82) | 18.7374 |
| 1990's | 1 (9.09) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (9.09) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Koren, G | 1 |
| ZOLNIKOV, SM | 1 |
| GOLUBEV, IS | 1 |
| PARFENOV, AP | 1 |
| Cullen, SM | 1 |
| Cronk, CE | 1 |
| Pueschel, SM | 1 |
| Schnell, RR | 1 |
| Reed, RB | 1 |
| Eskenazi, B | 1 |
| Bracken, MB | 1 |
| Mitchell, AA | 1 |
| Rosenberg, L | 1 |
| Shapiro, S | 1 |
| Slone, D | 1 |
| Boneva, RS | 1 |
| Moore, CA | 1 |
| Botto, L | 1 |
| Wong, LY | 1 |
| Erickson, JD | 1 |
| Check, WA | 1 |
| Shiono, PH | 1 |
| Klebanoff, MA | 1 |
| Zierler, S | 1 |
| Rothman, KJ | 1 |
| Hendrickx, AG | 1 |
| Cukierski, M | 1 |
| Prahalada, S | 1 |
| Janos, G | 1 |
| Rowland, J | 1 |
| Greene, C | 1 |
| Wilson, A | 1 |
| Shapira, E | 1 |
11 other studies available for pyridoxine and Heart Defects, Congenital
| Article | Year |
|---|---|
Treating morning sickness in the United States--changes in prescribing are needed.
Topics: Antiemetics; Dicyclomine; Doxylamine; Drug Approval; Drug Combinations; Female; Heart Defects, Conge | 2014 |
[USE OF PYRIDOXINE IN PATIENTS WITH RHEUMATIC HEART DEFECTS AND ITS INFLUENCE ON ANESTHESIA].
Topics: Anesthesia; Anesthesia, Endotracheal; Anesthesia, Intravenous; Anesthesiology; Barbiturates; Cardiac | 1964 |
Social development and feeding milestones of young Down syndrome children.
Topics: 5-Hydroxytryptophan; Child; Down Syndrome; Feeding Behavior; Female; Heart Defects, Congenital; Huma | 1981 |
Bendectin (Debendox) as a risk factor for pyloric stenosis.
Topics: Abnormalities, Drug-Induced; Adult; Dicyclomine; Doxylamine; Drug Combinations; Female; Heart Defect | 1982 |
Birth defects related to bendectin use in pregnancy. I. Oral clefts and cardiac defects.
Topics: Antiemetics; Cleft Lip; Cleft Palate; Dicyclomine; Doxylamine; Drug Combinations; Drug Evaluation; F | 1981 |
Nausea during pregnancy and congenital heart defects: a population-based case-control study.
Topics: Adolescent; Adult; Antiemetics; Case-Control Studies; Female; Georgia; Heart Defects, Congenital; Hu | 1999 |
CDC study: no evidence for teratogenicity of Bendectin.
Topics: Abnormalities, Drug-Induced; Antiemetics; Dicyclomine; Doxylamine; Drug Combinations; Female; Heart | 1979 |
Bendectin and human congenital malformations.
Topics: Abnormalities, Drug-Induced; Central Nervous System; Dicyclomine; Digestive System Abnormalities; Do | 1989 |
Congenital heart disease in relation to maternal use of Bendectin and other drugs in early pregnancy.
Topics: Acetaminophen; Adult; Anti-Bacterial Agents; Antiemetics; Aspirin; Dicyclomine; Doxylamine; Drug Com | 1985 |
Evaluation of bendectin embryotoxicity in nonhuman primates: I. Ventricular septal defects in prenatal macaques and baboon.
Topics: Animals; Dicyclomine; Dose-Response Relationship, Drug; Doxylamine; Drug Combinations; Female; Fetus | 1985 |
Prune belly syndrome and heart defect in one of monozygotic twins, following exposure to Tigan and Bendectin.
Topics: Benzamides; Dicyclomine; Doxylamine; Drug Combinations; Heart Defects, Congenital; Humans; Prune Bel | 1985 |