pyridoxine has been researched along with Harelip in 8 studies
4,5-bis(hydroxymethyl)-2-methylpyridin-3-ol: structure in first source
vitamin B6 : Any member of the group of pyridines that exhibit biological activity against vitamin B6 deficiency. Vitamin B6 deficiency is associated with microcytic anemia, electroencephalographic abnormalities, dermatitis with cheilosis (scaling on the lips and cracks at the corners of the mouth) and glossitis (swollen tongue), depression and confusion, and weakened immune function. Vitamin B6 consists of the vitamers pyridoxine, pyridoxal, and pyridoxamine and their respective 5'-phosphate esters (and includes their corresponding ionized and salt forms).
| Excerpt | Relevance | Reference |
|---|---|---|
| " The pregnancy was complicated by chronic maternal schizophrenia, severe toxaemia and maternal use of fluphenazine enanthate, dicyclomine hydrochloride, doxylamine succinate, pyridoxine hydrochloride and other drugs." | 7.66 | Multiple congenital abnormalities in a newborn boy associated with maternal use of fluphenazine enanthate and other drugs during pregnancy. ( Bury, RG; Donaldson, GL, 1982) |
| " The pregnancy was complicated by chronic maternal schizophrenia, severe toxaemia and maternal use of fluphenazine enanthate, dicyclomine hydrochloride, doxylamine succinate, pyridoxine hydrochloride and other drugs." | 3.66 | Multiple congenital abnormalities in a newborn boy associated with maternal use of fluphenazine enanthate and other drugs during pregnancy. ( Bury, RG; Donaldson, GL, 1982) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (75.00) | 18.7374 |
| 1990's | 1 (12.50) | 18.2507 |
| 2000's | 1 (12.50) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Krapels, IP | 1 |
| van Rooij, IA | 1 |
| Ocké, MC | 1 |
| van Cleef, BA | 1 |
| Kuijpers-Jagtman, AM | 2 |
| Steegers-Theunissen, RP | 2 |
| Donaldson, GL | 1 |
| Bury, RG | 1 |
| Mitchell, AA | 1 |
| Rosenberg, L | 1 |
| Shapiro, S | 1 |
| Slone, D | 1 |
| Wong, WY | 1 |
| Eskes, TK | 1 |
| Spauwen, PH | 1 |
| Steegers, EA | 1 |
| Thomas, CM | 1 |
| Hamel, BC | 1 |
| Blom, HJ | 1 |
| Briggs, RM | 1 |
| Elbourne, D | 2 |
| Mutch, L | 2 |
| Dauncey, M | 1 |
| Campbell, H | 1 |
| Samphier, M | 1 |
8 other studies available for pyridoxine and Harelip
| Article | Year |
|---|---|
Maternal dietary B vitamin intake, other than folate, and the association with orofacial cleft in the offspring.
Topics: Adult; Case-Control Studies; Cleft Lip; Cleft Palate; Diet; Energy Intake; Female; Folic Acid; Human | 2004 |
Multiple congenital abnormalities in a newborn boy associated with maternal use of fluphenazine enanthate and other drugs during pregnancy.
Topics: Abnormalities, Drug-Induced; Cleft Lip; Cleft Palate; Dicyclomine; Doxylamine; Female; Fluphenazine; | 1982 |
Birth defects related to bendectin use in pregnancy. I. Oral clefts and cardiac defects.
Topics: Antiemetics; Cleft Lip; Cleft Palate; Dicyclomine; Doxylamine; Drug Combinations; Drug Evaluation; F | 1981 |
Nonsyndromic orofacial clefts: association with maternal hyperhomocysteinemia.
Topics: Adult; Case-Control Studies; Child, Preschool; Cleft Lip; Cleft Palate; Erythrocytes; Fasting; Femal | 1999 |
Vitamin supplementation as a possible factor in the incidence of cleft lip/palate deformities in humans.
Topics: Ascorbic Acid; Calcium; Cleft Lip; Cleft Palate; Female; Folic Acid; Humans; Infant, Newborn; Matern | 1976 |
Congenital deformities associated with Bendectin.
Topics: Abnormalities, Drug-Induced; Adult; Cleft Lip; Cleft Palate; Cyclohexanecarboxylic Acids; Dicyclomin | 1977 |
Debendox.
Topics: Abnormalities, Drug-Induced; Antiemetics; Cleft Lip; Cleft Palate; Dicyclomine; Doxylamine; Drug Com | 1986 |
Debendox revisited.
Topics: Abnormalities, Drug-Induced; Antiemetics; Cleft Lip; Cleft Palate; Dicyclomine; Doxylamine; Drug Com | 1985 |