pyridoxine has been researched along with HIV Coinfection in 10 studies
4,5-bis(hydroxymethyl)-2-methylpyridin-3-ol: structure in first source
vitamin B6 : Any member of the group of pyridines that exhibit biological activity against vitamin B6 deficiency. Vitamin B6 deficiency is associated with microcytic anemia, electroencephalographic abnormalities, dermatitis with cheilosis (scaling on the lips and cracks at the corners of the mouth) and glossitis (swollen tongue), depression and confusion, and weakened immune function. Vitamin B6 consists of the vitamers pyridoxine, pyridoxal, and pyridoxamine and their respective 5'-phosphate esters (and includes their corresponding ionized and salt forms).
| Excerpt | Relevance | Reference |
|---|---|---|
| " It is evident that guidelines established for the prevention and treatment of this problem differ between industrialised and developing countries, and that further research is needed to define the optimum dosing of pyridoxine supplementation in populations where there is a significant burden of TB and HIV." | 6.47 | Polyneuropathy, anti-tuberculosis treatment and the role of pyridoxine in the HIV/AIDS era: a systematic review. ( Benatar, M; Harrison, TB; Heckmann, JM; van der Watt, JJ, 2011) |
| " It is evident that guidelines established for the prevention and treatment of this problem differ between industrialised and developing countries, and that further research is needed to define the optimum dosing of pyridoxine supplementation in populations where there is a significant burden of TB and HIV." | 2.47 | Polyneuropathy, anti-tuberculosis treatment and the role of pyridoxine in the HIV/AIDS era: a systematic review. ( Benatar, M; Harrison, TB; Heckmann, JM; van der Watt, JJ, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (40.00) | 18.2507 |
| 2000's | 1 (10.00) | 29.6817 |
| 2010's | 5 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hakim, J | 1 |
| Musiime, V | 1 |
| Szubert, AJ | 1 |
| Mallewa, J | 1 |
| Siika, A | 1 |
| Agutu, C | 1 |
| Walker, S | 1 |
| Pett, SL | 1 |
| Bwakura-Dangarembizi, M | 1 |
| Lugemwa, A | 1 |
| Kaunda, S | 1 |
| Karoney, M | 1 |
| Musoro, G | 1 |
| Kabahenda, S | 1 |
| Nathoo, K | 1 |
| Maitland, K | 1 |
| Griffiths, A | 1 |
| Thomason, MJ | 1 |
| Kityo, C | 1 |
| Mugyenyi, P | 1 |
| Prendergast, AJ | 1 |
| Walker, AS | 1 |
| Gibb, DM | 1 |
| Tincati, C | 1 |
| Savoldi, A | 1 |
| Cannizzo, ES | 1 |
| Bellistrì, GM | 1 |
| Termini, R | 1 |
| Garau, M | 1 |
| Mancusi, D | 1 |
| d'Arminio Monforte, A | 1 |
| Marchetti, G | 1 |
| van der Watt, JJ | 2 |
| Benatar, MG | 1 |
| Harrison, TB | 2 |
| Carrara, H | 1 |
| Heckmann, JM | 2 |
| Fielding, KL | 1 |
| Grant, AD | 1 |
| Hayes, RJ | 1 |
| Chaisson, RE | 1 |
| Corbett, EL | 1 |
| Churchyard, GJ | 1 |
| Benatar, M | 1 |
| Visser, ME | 1 |
| Texeira-Swiegelaar, C | 1 |
| Maartens, G | 1 |
| Pape, JW | 1 |
| Jean, SS | 1 |
| Ho, JL | 1 |
| Hafner, A | 1 |
| Johnson, WD | 1 |
| Fisher, M | 1 |
| Tomlinson, DR | 1 |
| Coker, RJ | 1 |
| Salhany, JM | 1 |
| Stevenson, M | 1 |
| James, JS | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| PROvide MIner-friendly SErvices for Integrated TB/HIV Care in Lesotho Study (PROMISE Study)[NCT03537872] | 248 participants (Actual) | Interventional | 2018-03-13 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for pyridoxine and HIV Coinfection
| Article | Year |
|---|---|
Polyneuropathy, anti-tuberculosis treatment and the role of pyridoxine in the HIV/AIDS era: a systematic review.
Topics: Antitubercular Agents; HIV Infections; Humans; Isoniazid; Polyneuropathies; Practice Guidelines as T | 2011 |
Hypothesis: potential utility of pyridoxal 5'-phosphate (vitamin B6) and levamisole in immune modulation and HIV-1 infection.
Topics: Adjuvants, Immunologic; CD4 Lymphocyte Count; HIV Infections; HIV-1; Humans; Levamisole; Pyridoxal P | 1996 |
4 trials available for pyridoxine and HIV Coinfection
| Article | Year |
|---|---|
Enhanced Prophylaxis plus Antiretroviral Therapy for Advanced HIV Infection in Africa.
Topics: Adolescent; Adult; Africa South of the Sahara; Aged; AIDS-Related Opportunistic Infections; Anti-Inf | 2017 |
Thibela TB: design and methods of a cluster randomised trial of the effect of community-wide isoniazid preventive therapy on tuberculosis amongst gold miners in South Africa.
Topics: AIDS-Related Opportunistic Infections; Antitubercular Agents; Female; Gold; HIV Infections; Humans; | 2011 |
The short-term effects of anti-tuberculosis therapy on plasma pyridoxine levels in patients with pulmonary tuberculosis.
Topics: Adult; Antitubercular Agents; Ethambutol; Female; Follow-Up Studies; HIV Infections; Humans; Isoniaz | 2004 |
Effect of isoniazid prophylaxis on incidence of active tuberculosis and progression of HIV infection.
Topics: Acquired Immunodeficiency Syndrome; Adult; AIDS-Related Opportunistic Infections; Drug Therapy, Comb | 1993 |
4 other studies available for pyridoxine and HIV Coinfection
| Article | Year |
|---|---|
T-cell phenotype and function following a first cART regimen containing either a protease inhibitor or a non-nucleoside reverse transcriptase inhibitor in HIV-infected late presenters: results from a retrospective, ex vivo study.
Topics: Adult; Anti-HIV Agents; Ascorbic Acid; Darunavir; Drug Combinations; Female; HIV Infections; HIV Pro | 2016 |
Isoniazid exposure and pyridoxine levels in human immunodeficiency virus associated distal sensory neuropathy.
Topics: Adult; Antiretroviral Therapy, Highly Active; Arylamine N-Acetyltransferase; Coinfection; Female; HI | 2015 |
The management of mycobacterial infections in HIV seropositive individuals. Jefferiss Wing Therapeutics and Protocols Group.
Topics: Adrenal Cortex Hormones; Amikacin; Anti-Bacterial Agents; Anti-Infective Agents; Antibiotics, Antitu | 1996 |
Neuropathy: nutritional prevention/treatment suggested.
Topics: Anti-HIV Agents; Calcium; HIV Infections; Humans; Magnesium; Peripheral Nervous System Diseases; Pyr | 1999 |