pyridoxine has been researched along with Genetic Diseases in 3 studies
4,5-bis(hydroxymethyl)-2-methylpyridin-3-ol: structure in first source
vitamin B6 : Any member of the group of pyridines that exhibit biological activity against vitamin B6 deficiency. Vitamin B6 deficiency is associated with microcytic anemia, electroencephalographic abnormalities, dermatitis with cheilosis (scaling on the lips and cracks at the corners of the mouth) and glossitis (swollen tongue), depression and confusion, and weakened immune function. Vitamin B6 consists of the vitamers pyridoxine, pyridoxal, and pyridoxamine and their respective 5'-phosphate esters (and includes their corresponding ionized and salt forms).
| Excerpt | Relevance | Reference |
|---|---|---|
| "An abnormality in the pyridoxal-5'-phosphate (PLP) dependent enzyme, glutamic acid decarboxylase (GAD), which synthesizes gamma-aminobutyric acid (GABA), may underlie the epileptic syndrome of pyridoxine-dependent seizures." | 7.69 | Reduced GABA synthesis in pyridoxine-dependent seizures. ( Gospe, SM; Keen, CL; Olin, KL, 1994) |
| "An abnormality in the pyridoxal-5'-phosphate (PLP) dependent enzyme, glutamic acid decarboxylase (GAD), which synthesizes gamma-aminobutyric acid (GABA), may underlie the epileptic syndrome of pyridoxine-dependent seizures." | 3.69 | Reduced GABA synthesis in pyridoxine-dependent seizures. ( Gospe, SM; Keen, CL; Olin, KL, 1994) |
| " (1) The chronic administration of isoniazid for the prevention or treatment of tuberculosis can produce peripheral neuropathy which can be prevented by the concurrent administration of pyridoxine." | 2.36 | Drug-pyridoxal phosphate interactions. ( Al-Sayegh, A; Ebadi, M; Gessert, CF, 1982) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (66.67) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ebadi, M | 1 |
| Gessert, CF | 1 |
| Al-Sayegh, A | 1 |
| Mudd, SH | 1 |
| Gospe, SM | 1 |
| Olin, KL | 1 |
| Keen, CL | 1 |
2 reviews available for pyridoxine and Genetic Diseases
| Article | Year |
|---|---|
Drug-pyridoxal phosphate interactions.
Topics: Animals; Contraceptives, Oral, Hormonal; Depressive Disorder; Disease; Drug Interactions; Drug Thera | 1982 |
Vitamin-responsive genetic abnormalities.
Topics: 3-Methyl-2-Oxobutanoate Dehydrogenase (Lipoamide); Apoenzymes; Cystathionine beta-Synthase; Genetic | 1982 |
1 other study available for pyridoxine and Genetic Diseases
| Article | Year |
|---|---|
Reduced GABA synthesis in pyridoxine-dependent seizures.
Topics: Administration, Oral; Electroencephalography; Female; Fibroblasts; gamma-Aminobutyric Acid; Genetic | 1994 |