pyridoxine has been researched along with Galactorrhea in 12 studies
4,5-bis(hydroxymethyl)-2-methylpyridin-3-ol: structure in first source
vitamin B6 : Any member of the group of pyridines that exhibit biological activity against vitamin B6 deficiency. Vitamin B6 deficiency is associated with microcytic anemia, electroencephalographic abnormalities, dermatitis with cheilosis (scaling on the lips and cracks at the corners of the mouth) and glossitis (swollen tongue), depression and confusion, and weakened immune function. Vitamin B6 consists of the vitamers pyridoxine, pyridoxal, and pyridoxamine and their respective 5'-phosphate esters (and includes their corresponding ionized and salt forms).
Galactorrhea: Excessive or inappropriate LACTATION in females or males, and not necessarily related to PREGNANCY. Galactorrhea can occur either unilaterally or bilaterally, and be profuse or sparse. Its most common cause is HYPERPROLACTINEMIA.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Sixteen patients, eight with acromegaly and eight with galactorrhea, were treated with pyridoxine (600 mg/day) for a three-month period." | 7.66 | Superiority of bromocriptine over pyridoxine in the treatment of patients with acromegaly or galactorrhea. ( Blum, I; Chowers, I; Kaufman, H; Sagiv, M; Segal, S; Shalit, M, 1980) |
| "The acute effect of pyridoxine (B6) on serum GH and PRL levels and its chronic effects on galactorrhea in nine subjects (group I, n=4, idiopathic galactorrhea with normal PRL levels and normal menses; Group II, n=5, galactorrhea-amenorrhea with increased PRL levels) have been studied." | 7.65 | Ineffectiveness of pyridoxine (B6) to alter secretion of growth hormone and prolactin and absence of therapeutic effects on galactorrhea-amenorrhea syndromes. ( Guyda, H; Laliberté, R; Naftolin, F; Tolis, G, 1977) |
| "Three women with the galactorrhea-amenorrhea syndrome and elevated prolactin concentrations experienced a return of regular ovulatory menses within 37-94 days after starting pyridoxine treatment (200-600 mg/day)." | 7.65 | Treatment of women with the galactorrhea-amenorrhea syndrome with pyridoxine (vitamin B6). ( McIntosh, EN, 1976) |
| "Sixteen patients, eight with acromegaly and eight with galactorrhea, were treated with pyridoxine (600 mg/day) for a three-month period." | 3.66 | Superiority of bromocriptine over pyridoxine in the treatment of patients with acromegaly or galactorrhea. ( Blum, I; Chowers, I; Kaufman, H; Sagiv, M; Segal, S; Shalit, M, 1980) |
| "The acute effect of pyridoxine (B6) on serum GH and PRL levels and its chronic effects on galactorrhea in nine subjects (group I, n=4, idiopathic galactorrhea with normal PRL levels and normal menses; Group II, n=5, galactorrhea-amenorrhea with increased PRL levels) have been studied." | 3.65 | Ineffectiveness of pyridoxine (B6) to alter secretion of growth hormone and prolactin and absence of therapeutic effects on galactorrhea-amenorrhea syndromes. ( Guyda, H; Laliberté, R; Naftolin, F; Tolis, G, 1977) |
| "Three women with the galactorrhea-amenorrhea syndrome and elevated prolactin concentrations experienced a return of regular ovulatory menses within 37-94 days after starting pyridoxine treatment (200-600 mg/day)." | 3.65 | Treatment of women with the galactorrhea-amenorrhea syndrome with pyridoxine (vitamin B6). ( McIntosh, EN, 1976) |
| "Pyridoxine has been reported as having an antilactogenic effect, presumably by suppressing prolactin secretion." | 2.64 | Failure of pyridoxine to suppress raised serum prolactin levels. ( de Waal, JM; Harms, JH; Pannall, PR; Slabber, CF; Steyn, AF, 1978) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 12 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kidd, GS | 1 |
| Dimond, R | 1 |
| Kark, JA | 1 |
| Whorton, N | 1 |
| Vigersky, RA | 1 |
| Blum, I | 1 |
| Segal, S | 1 |
| Kaufman, H | 1 |
| Sagiv, M | 1 |
| Shalit, M | 1 |
| Chowers, I | 1 |
| Presl, J | 1 |
| Tolis, G | 1 |
| Laliberté, R | 1 |
| Guyda, H | 1 |
| Naftolin, F | 1 |
| Goodenow, TJ | 1 |
| Malarkey, WB | 1 |
| Schindler, AE | 1 |
| Plieninger, M | 1 |
| Zubke, W | 1 |
| Göser, R | 1 |
| Keller, E | 1 |
| Bercovici, JP | 1 |
| Darragon, T | 1 |
| Khoury, S | 1 |
| Caroff, J | 1 |
| Lehtovirta, P | 1 |
| Ranta, T | 1 |
| Seppälä, M | 1 |
| de Waal, JM | 1 |
| Steyn, AF | 1 |
| Harms, JH | 1 |
| Slabber, CF | 1 |
| Pannall, PR | 1 |
| McIntosh, EN | 1 |
| Dickey, RP | 1 |
| Stone, SC | 1 |
| DeVane, GW | 1 |
| Guzick, DS | 1 |
1 review available for pyridoxine and Galactorrhea
| Article | Year |
|---|---|
Drugs that affect the breast and lactation.
Topics: Androgens; Apomorphine; Barbiturates; Breast; Breast Neoplasms; Bromocriptine; Contraceptives, Oral, | 1975 |
2 trials available for pyridoxine and Galactorrhea
| Article | Year |
|---|---|
Failure of pyridoxine to suppress raised serum prolactin levels.
Topics: Chlorpromazine; Female; Galactorrhea; Humans; Lactation; Metabolic Diseases; Pregnancy; Prolactin; P | 1978 |
Bromocriptine therapy in normoprolactinemic women with unexplained infertility and galactorrhea.
Topics: Adult; Analysis of Variance; Bromocriptine; Clomiphene; Drug Therapy, Combination; Female; Follow-Up | 1986 |
9 other studies available for pyridoxine and Galactorrhea
| Article | Year |
|---|---|
The effects of pyridoxine on pituitary hormone secretion in amenorrhea-galactorrhea syndromes.
Topics: Adult; Amenorrhea; Chlorpromazine; Female; Galactorrhea; Humans; Lactation Disorders; Levodopa; Pitu | 1982 |
Superiority of bromocriptine over pyridoxine in the treatment of patients with acromegaly or galactorrhea.
Topics: Acromegaly; Adult; Aged; Blood Pressure; Bromocriptine; Drug Evaluation; Female; Galactorrhea; Human | 1980 |
[Pyridoxine and hyperprolactinemia].
Topics: Amenorrhea; Animals; Female; Galactorrhea; Haplorhini; Humans; Pregnancy; Prolactin; Pyridoxine; Syn | 1979 |
Ineffectiveness of pyridoxine (B6) to alter secretion of growth hormone and prolactin and absence of therapeutic effects on galactorrhea-amenorrhea syndromes.
Topics: Amenorrhea; Bromocriptine; Female; Galactorrhea; Growth Hormone; Humans; Lactation Disorders; Menstr | 1977 |
Ineffectiveness of pyridoxine in evaluation and treatment of the hyperprolactinemic amenorrhea-galactorrhea syndrome.
Topics: Administration, Oral; Adult; Amenorrhea; Drug Evaluation; Female; Galactorrhea; Humans; Injections, | 1979 |
[Longtime study on bromoergocryptine therapy and pyridoxine therapy of amenorrhea-galactorrhea].
Topics: Amenorrhea; Bromocriptine; Female; Galactorrhea; Humans; Lactation Disorders; Pregnancy; Pyridoxine; | 1979 |
[Female hyperprolactinaemia. 19 cases (author's transl)].
Topics: Adolescent; Adult; Amenorrhea; Bromocriptine; Female; Galactorrhea; Humans; Pituitary Gland; Pregnan | 1979 |
Pyridoxine treatment of galactorrhoea-amenorrhoea syndromes.
Topics: Adult; Amenorrhea; Drug Evaluation; Female; Galactorrhea; Humans; Lactation Disorders; Ovulation; Pr | 1978 |
Treatment of women with the galactorrhea-amenorrhea syndrome with pyridoxine (vitamin B6).
Topics: Adult; Amenorrhea; Female; Galactorrhea; Humans; Lactation Disorders; Menstruation; Pregnancy; Prola | 1976 |