pyridoxine has been researched along with Fetal Death in 11 studies
4,5-bis(hydroxymethyl)-2-methylpyridin-3-ol: structure in first source
vitamin B6 : Any member of the group of pyridines that exhibit biological activity against vitamin B6 deficiency. Vitamin B6 deficiency is associated with microcytic anemia, electroencephalographic abnormalities, dermatitis with cheilosis (scaling on the lips and cracks at the corners of the mouth) and glossitis (swollen tongue), depression and confusion, and weakened immune function. Vitamin B6 consists of the vitamers pyridoxine, pyridoxal, and pyridoxamine and their respective 5'-phosphate esters (and includes their corresponding ionized and salt forms).
Fetal Death: Death of the developing young in utero. BIRTH of a dead FETUS is STILLBIRTH.
| Excerpt | Relevance | Reference |
|---|---|---|
| ""Perinatal" hypophosphatasia is the most severe form of this inborn error of metabolism, which is characterized by deficient activity of the tissue-nonspecific (liver/bone/kidney) isoenzyme of alkaline phosphatase (ALP) (TNSALP)." | 5.27 | Perinatal hypophosphatasia: tissue levels of vitamin B6 are unremarkable despite markedly increased circulating concentrations of pyridoxal-5'-phosphate. Evidence for an ectoenzyme role for tissue-nonspecific alkaline phosphatase. ( Coburn, SP; Cole, FS; Fedde, KN; Mahuren, JD; McCabe, ER; Whyte, MP, 1988) |
| ""Perinatal" hypophosphatasia is the most severe form of this inborn error of metabolism, which is characterized by deficient activity of the tissue-nonspecific (liver/bone/kidney) isoenzyme of alkaline phosphatase (ALP) (TNSALP)." | 1.27 | Perinatal hypophosphatasia: tissue levels of vitamin B6 are unremarkable despite markedly increased circulating concentrations of pyridoxal-5'-phosphate. Evidence for an ectoenzyme role for tissue-nonspecific alkaline phosphatase. ( Coburn, SP; Cole, FS; Fedde, KN; Mahuren, JD; McCabe, ER; Whyte, MP, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (90.91) | 18.7374 |
| 1990's | 1 (9.09) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Clarke, M | 1 |
| Clayton, DG | 1 |
| Lubbers, MF | 1 |
| Aarnoudse, JG | 1 |
| van Doormaal, JJ | 1 |
| Milkovich, L | 1 |
| van den Berg, BJ | 1 |
| Khera, KS | 1 |
| Whyte, MP | 1 |
| Mahuren, JD | 1 |
| Fedde, KN | 1 |
| Cole, FS | 1 |
| McCabe, ER | 1 |
| Coburn, SP | 1 |
| Porter, JB | 1 |
| Hunter-Mitchell, J | 1 |
| Jick, H | 1 |
| Walker, AM | 1 |
| Mahmoud, F | 1 |
| De Silva, K | 1 |
| Driskell, JA | 1 |
| Strickland, LA | 1 |
| Poon, CH | 1 |
| Foshee, DP | 1 |
| Clarke, HC | 1 |
| Heller, S | 1 |
| Salkeld, RM | 1 |
| Körner, WF | 1 |
| Lee, SH | 1 |
| Aleyassine, H | 1 |
1 trial available for pyridoxine and Fetal Death
| Article | Year |
|---|---|
An evaluation of the teratogenicity of certain antinauseant drugs.
Topics: Abnormalities, Drug-Induced; Antiemetics; Clinical Trials as Topic; Cyclizine; Dicyclomine; Doxylami | 1976 |
10 other studies available for pyridoxine and Fetal Death
| Article | Year |
|---|---|
Safety of Debendox.
Topics: Abnormalities, Drug-Induced; Dicyclomine; Doxylamine; Drug Combinations; Female; Fetal Death; Humans | 1981 |
[Obstetric problems followed by stroke].
Topics: Abortion, Habitual; Adult; Arteriosclerosis; Cerebral Infarction; Diagnosis, Differential; Female; F | 1999 |
Teratogenicity study in rats given high doses of pyridoxine (vitamin B6) during organogenesis.
Topics: Abnormalities, Drug-Induced; Administration, Oral; Animals; Dose-Response Relationship, Drug; Female | 1975 |
Perinatal hypophosphatasia: tissue levels of vitamin B6 are unremarkable despite markedly increased circulating concentrations of pyridoxal-5'-phosphate. Evidence for an ectoenzyme role for tissue-nonspecific alkaline phosphatase.
Topics: Alkaline Phosphatase; Female; Fetal Death; Humans; Hypophosphatasia; Infant, Newborn; Male; Pregnanc | 1988 |
Drugs and stillbirth.
Topics: Abnormalities, Drug-Induced; Adult; Anti-Bacterial Agents; Contraceptives, Oral; Dicyclomine; Doxyla | 1986 |
Herpes gestationis.
Topics: Dermatitis Herpetiformis; Female; Fetal Death; Humans; Prednisolone; Pregnancy; Pregnancy Complicati | 1972 |
The vitamin B 6 requirement of the male rat as determined by behavioral patterns, brain pyridoxal phosphate and nucleic acid composition and erythrocyte alanine aminotransferase activity.
Topics: Age Factors; Alanine Transaminase; Animals; Behavior, Animal; Brain; DNA; Dose-Response Relationship | 1973 |
B-vitamins in human amniotic fluid.
Topics: Amniocentesis; Amniotic Fluid; Female; Fetal Death; Folic Acid; Humans; Pre-Eclampsia; Pregnancy; Py | 1973 |
Vitamin B6 status in pregnancy.
Topics: Abortion, Spontaneous; Adolescent; Adult; Aspartate Aminotransferases; Birth Weight; Diabetes Mellit | 1973 |
Hydrazine toxicity in pregnant rats.
Topics: Animals; Body Weight; Embryonic and Fetal Development; Female; Fetal Death; Fetus; Gestational Age; | 1970 |