Page last updated: 2024-10-20

pyridoxine and Fatty Liver

pyridoxine has been researched along with Fatty Liver in 15 studies

4,5-bis(hydroxymethyl)-2-methylpyridin-3-ol: structure in first source
vitamin B6 : Any member of the group of pyridines that exhibit biological activity against vitamin B6 deficiency. Vitamin B6 deficiency is associated with microcytic anemia, electroencephalographic abnormalities, dermatitis with cheilosis (scaling on the lips and cracks at the corners of the mouth) and glossitis (swollen tongue), depression and confusion, and weakened immune function. Vitamin B6 consists of the vitamers pyridoxine, pyridoxal, and pyridoxamine and their respective 5'-phosphate esters (and includes their corresponding ionized and salt forms).

Fatty Liver: Lipid infiltration of the hepatic parenchymal cells resulting in a yellow-colored liver. The abnormal lipid accumulation is usually in the form of TRIGLYCERIDES, either as a single large droplet or multiple small droplets. Fatty liver is caused by an imbalance in the metabolism of FATTY ACIDS.

Research Excerpts

ExcerptRelevanceReference
"The therapeutic effect of metadoxine on alcoholic and non-alcoholic steatohepatitis."8.82[The therapeutic effect of metadoxine on alcoholic and non-alcoholic steatohepatitis]. ( Blázovics, A; Fehér, J; Váli, L, 2005)
"The therapeutic effect of metadoxine on alcoholic and non-alcoholic steatohepatitis."4.82[The therapeutic effect of metadoxine on alcoholic and non-alcoholic steatohepatitis]. ( Blázovics, A; Fehér, J; Váli, L, 2005)

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-199010 (66.67)18.7374
1990's1 (6.67)18.2507
2000's3 (20.00)29.6817
2010's1 (6.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kaimoto, T1
Shibuya, M1
Nishikawa, K1
Maeda, H1
Pal'tsev, AI1
Sharapov, IV1
Gorbunova, EN1
Khomchenko, TN1
Kurganova, IV1
Soldatova, GS1
Eremina, AA1
Nikolaev, IuA1
FARBER, S1
VAWTER, GF1
REID, ME1
WIZGIRD, JP1
GREENBERG, LD1
MOON, HD1
Leevy, CM2
Baker, H3
Tenhove, W1
Frank, O2
Cherrick, GR1
Váli, L1
Blázovics, A1
Fehér, J1
Ki, SH1
Choi, JH1
Kim, CW1
Kim, SG1
Marchi, S1
Polloni, A1
Costa, F1
Bellini, M1
Bonifazi, V1
Tumino, E1
Grassi, B1
Romano, MR1
De Bartolo, G1
Bertelli, A1
Petzold, H1
Weigel, K1
Pluvinage, R1
Luisada-Opper, A1
Sorrell, MF1
Thomson, AD1
Okada, M1
Ochi, A1
Yamada, K1
Kuzuya, F1
Yokoyama, T1
Oguri, T1
Okura, Y1
Yoshimine, N1
Mizuno, S1
Kuno, K1
Kitagawa, M1

Reviews

1 review available for pyridoxine and Fatty Liver

ArticleYear
[The therapeutic effect of metadoxine on alcoholic and non-alcoholic steatohepatitis].
    Orvosi hetilap, 2005, Nov-20, Volume: 146, Issue:47

    Topics: Alcohol Deterrents; Alcoholic Intoxication; Alcoholism; Drug Combinations; Fatty Liver; Fatty Liver,

2005

Trials

1 trial available for pyridoxine and Fatty Liver

ArticleYear
[Non-alcoholic fatty liver disease: age peculiarities, breakthrough in pathogenetic therapy].
    Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology, 2009, Issue:8

    Topics: Adult; Aged; Aging; Drug Combinations; Fatty Liver; Humans; Middle Aged; Pyridoxine; Pyrrolidonecarb

2009

Other Studies

13 other studies available for pyridoxine and Fatty Liver

ArticleYear
High incidence of lipid deposition in the liver of rats fed a diet supplemented with branched-chain amino acids under vitamin B6 deficiency.
    Journal of nutritional science and vitaminology, 2013, Volume: 59, Issue:1

    Topics: Amino Acids, Branched-Chain; Animals; Apolipoproteins B; Apolipoproteins E; Caseins; Cholesterol; Ch

2013
THE CHILDREN'S HOSPITAL MEDICAL CENTER, BOSTON, MASS.
    The Journal of pediatrics, 1964, Volume: 64

    Topics: Asphyxia Neonatorum; Boston; Child; Fatty Liver; Hospitals; Hospitals, Pediatric; Humans; Infant; In

1964
NUTRITIONAL STUDIES WITH THE GUINEA PIGS. XI. PYRIDOXINE.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1964, Volume: 116

    Topics: Adrenal Gland Diseases; Animals; Cecum; Fatty Liver; Genitalia; Guinea Pigs; Intestine, Large; Intes

1964
HEPATIC LESIONS IN PYRIDOXINE-DEFICIENT MONKEYS.
    Archives of pathology, 1965, Volume: 79

    Topics: Amino Acids; Animals; Fatty Liver; Haplorhini; Liver; Liver Cirrhosis; Necrosis; Pathology; Proteins

1965
B-COMPLEX VITAMINS IN LIVER DISEASE OF THE ALCOHOLIC.
    The American journal of clinical nutrition, 1965, Volume: 16

    Topics: Alcoholism; Autoradiography; Biopsy; Biotin; Blood Chemical Analysis; DNA; Drug Therapy; Fatty Liver

1965
Combined metadoxine and garlic oil treatment efficaciously abrogates alcoholic steatosis and CYP2E1 induction in rat liver with restoration of AMPK activity.
    Chemico-biological interactions, 2007, Aug-30, Volume: 169, Issue:2

    Topics: Adenylate Kinase; Alcoholism; Allyl Compounds; Animals; Cytochrome P-450 CYP2E1; Drug Combinations;

2007
Liver triglyceride accumulation after chronic ethanol administration: a possible protective role of metadoxina and ubiquinone.
    International journal of tissue reactions, 1990, Volume: 12, Issue:4

    Topics: Animals; Drug Combinations; Ethanol; Fatty Liver; Liver; Male; Osmolar Concentration; Pyridoxine; Py

1990
[Influence of B complex vitamins on experimental liver damage in rats].
    Internationale Zeitschrift fur Vitaminforschung. International journal of vitamin research. Journal international de vitaminologie, 1968, Volume: 38, Issue:1

    Topics: Acid Phosphatase; Adenosine Triphosphatases; Alkaline Phosphatase; Animals; Carbon Tetrachloride Poi

1968
[Study of the therapeutic action of a combination of vitamins B1, B6 and hydroxocobalamin in large doses].
    La semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de Paris, 1968, Jan-20, Volume: 44, Issue:4

    Topics: Adult; Aged; Anemia; Brain Diseases; Epilepsy; Facial Paralysis; Fatty Liver; Female; Hemiplegia; He

1968
Nutritional deficiencies in liver disease.
    The Medical clinics of North America, 1970, Volume: 54, Issue:2

    Topics: Carcinoma, Hepatocellular; Diet Therapy; Fatty Liver; Hepatitis; Humans; Liver Cirrhosis; Liver Dise

1970
Vitamin deficits in severe alcoholic fatty liver of man calculated from multiple reference units.
    Experimental and molecular pathology, 1971, Volume: 15, Issue:2

    Topics: Alcoholism; Autopsy; Biotin; DNA; Fatty Liver; Folic Acid; Humans; Nicotinic Acids; Pantothenic Acid

1971
The effect of dietary protein level on transaminase activities and fat deposition in vitamin B 6 -depleted rat liver.
    Journal of biochemistry, 1971, Volume: 70, Issue:4

    Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Caseins; Cortisone; Dietary Proteins; Fa

1971
Effects of vitamin B6 and safflower oil on dietarily induced hyperlipemia and fat in the liver of rats.
    The Journal of vitaminology, 1965, Sep-10, Volume: 11, Issue:3

    Topics: Animals; Fatty Acids, Essential; Fatty Liver; Hyperlipidemias; Pyridoxine; Rats

1965