pyridoxine has been researched along with Experimental Hepatoma in 14 studies
4,5-bis(hydroxymethyl)-2-methylpyridin-3-ol: structure in first source
vitamin B6 : Any member of the group of pyridines that exhibit biological activity against vitamin B6 deficiency. Vitamin B6 deficiency is associated with microcytic anemia, electroencephalographic abnormalities, dermatitis with cheilosis (scaling on the lips and cracks at the corners of the mouth) and glossitis (swollen tongue), depression and confusion, and weakened immune function. Vitamin B6 consists of the vitamers pyridoxine, pyridoxal, and pyridoxamine and their respective 5'-phosphate esters (and includes their corresponding ionized and salt forms).
| Excerpt | Relevance | Reference |
|---|---|---|
| "The growth of 9A and 7316A Morris hepatomas was studied in pyridoxine (PN)-depleted and in pair-fed control Buffalo rats." | 1.26 | Control of tumor growth by pyridoxine restriction or treatment with an antivitamin agent. ( Tryfiates, GP, 1981) |
| "Control rats or rats bearing Morris hepatoma 5123C (intact), 5123C (adrenalectomized), 7794A, 7800, 8999, 9121, or 9618A were fed a purified diet either deficient or adequate for vitamin B6." | 1.26 | Effects of dietary vitamin B6 on the in vitro inactivation of rat tyrosine aminotransferase in host liver and Morris hepatomas. ( Morris, HP; Reynolds, RD, 1979) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 13 (92.86) | 18.7374 |
| 1990's | 1 (7.14) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Meisler, NT | 5 |
| Nutter, LM | 2 |
| Thanassi, JW | 6 |
| Watanabe, A | 1 |
| Nagashima, H | 1 |
| Commers, P | 1 |
| Chiu, JF | 1 |
| Tryfiates, GP | 4 |
| Bishop, R | 1 |
| Smith, RR | 1 |
| Morris, HP | 2 |
| Sonidis, GP | 1 |
| Sattsangi, S | 1 |
| DiSorbo, DM | 2 |
| Paavola, LG | 1 |
| Litwack, G | 2 |
| Reynolds, RD | 1 |
| Kittler, JM | 1 |
2 reviews available for pyridoxine and Experimental Hepatoma
| Article | Year |
|---|---|
Vitamin B6 and cancer (review).
Topics: Animals; Biotransformation; Cell Division; Fluorodeoxyuridylate; Fluorouracil; Liver Neoplasms, Expe | 1981 |
Metabolism of pyridoxine in hepatomas.
Topics: Animals; Carrier Proteins; Liver; Liver Neoplasms, Experimental; Liver Regeneration; Pyridoxal Phosp | 1990 |
12 other studies available for pyridoxine and Experimental Hepatoma
| Article | Year |
|---|---|
Vitamin B6 metabolism in liver and liver-derived tumors.
Topics: Animals; Dexamethasone; Female; Liver; Liver Neoplasms, Experimental; Ornithine Decarboxylase; Phosp | 1982 |
Altered dynamics of alpha-fetoprotein production following pyridoxine and adenosine 5'-triphosphate administration to cirrhotic patients with or without primary hepatomas and to liver-injured and hepatoma-bearing rats.
Topics: Adenosine Triphosphate; alpha-Fetoproteins; Animals; Carbon Tetrachloride Poisoning; Carcinoma, Hepa | 1981 |
Vitamin B6 metabolism in Morris hepatomas.
Topics: Animals; Female; Kinetics; Liver; Liver Neoplasms, Experimental; Ornithine Decarboxylase; Phosphoric | 1981 |
Immunological studies involving vitamin B-6 and Morris hepatomas.
Topics: Animals; Antibodies, Monoclonal; Carrier Proteins; Enzyme-Linked Immunosorbent Assay; Immunosorbent | 1984 |
Novel vitamin B6 tumor metabolites.
Topics: Animals; Chromatography, High Pressure Liquid; Gas Chromatography-Mass Spectrometry; Liver Neoplasms | 1984 |
Separation of vitamin B6 compounds by paired-ion high-performance liquid chromatography.
Topics: Animals; Chromatography, High Pressure Liquid; Liver Neoplasms, Experimental; Pyridoxine | 1982 |
Pyridoxine resistance in a rat hepatoma cell line.
Topics: Animals; Biological Transport; Cell Line; Clone Cells; Drug Resistance; Kinetics; Liver Neoplasms, E | 1982 |
Vitamin B6 kills hepatoma cells in culture.
Topics: Adenosine Triphosphate; Animals; Antineoplastic Agents; Breast Neoplasms; Cell Count; Cell Division; | 1982 |
Control of tumor growth by pyridoxine restriction or treatment with an antivitamin agent.
Topics: Animals; Female; Liver Neoplasms, Experimental; Neoplasms, Experimental; Penicillamine; Pyridoxine; | 1981 |
Effects of dietary vitamin B6 on the in vitro inactivation of rat tyrosine aminotransferase in host liver and Morris hepatomas.
Topics: Animals; Cysteine; In Vitro Techniques; Kinetics; Liver; Liver Neoplasms, Experimental; Male; Pyrido | 1979 |
Azo dye-induced alterations in vitamin B-6 metabolism and in pyridoxal 5'-phosphate-binding proteins in rat liver.
Topics: Animals; Cytosol; Densitometry; Enzyme-Linked Immunosorbent Assay; Liver; Liver Neoplasms, Experimen | 1986 |
Vitamin B6 metabolism in McA-RH7777 cells.
Topics: Animals; Liver; Liver Neoplasms, Experimental; Pyridoxal Kinase; Pyridoxal Phosphate; Pyridoxamineph | 1988 |