pyridoxine has been researched along with Epilepsy, Tonic-Clonic in 13 studies
4,5-bis(hydroxymethyl)-2-methylpyridin-3-ol: structure in first source
vitamin B6 : Any member of the group of pyridines that exhibit biological activity against vitamin B6 deficiency. Vitamin B6 deficiency is associated with microcytic anemia, electroencephalographic abnormalities, dermatitis with cheilosis (scaling on the lips and cracks at the corners of the mouth) and glossitis (swollen tongue), depression and confusion, and weakened immune function. Vitamin B6 consists of the vitamers pyridoxine, pyridoxal, and pyridoxamine and their respective 5'-phosphate esters (and includes their corresponding ionized and salt forms).
Epilepsy, Tonic-Clonic: A generalized seizure disorder characterized by recurrent major motor seizures. The initial brief tonic phase is marked by trunk flexion followed by diffuse extension of the trunk and extremities. The clonic phase features rhythmic flexor contractions of the trunk and limbs, pupillary dilation, elevations of blood pressure and pulse, urinary incontinence, and tongue biting. This is followed by a profound state of depressed consciousness (post-ictal state) which gradually improves over minutes to hours. The disorder may be cryptogenic, familial, or symptomatic (caused by an identified disease process). (From Adams et al., Principles of Neurology, 6th ed, p329)
Excerpt | Relevance | Reference |
---|---|---|
"A 14-yr old previously healthy girl receiving preventive isoniazid therapy who suddenly developed generalized tonic-clonic seizures and coma." | 3.70 | Acute isoniazid neurotoxicity during preventive therapy. ( Gorjup, V; Horvat, M; Martinjak-Dvorsek, I; Noc, M, 2000) |
"A 11-year-old girl suffering from grand mal epilepsy underwent antiepileptic therapy with carbamazepine (600 mg/daily)." | 1.30 | [Dose-dependent pellagroid skin reaction caused by carbamazepine]. ( Heyer, G; Schell, H; Simon, M, 1998) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 6 (46.15) | 18.7374 |
1990's | 1 (7.69) | 18.2507 |
2000's | 5 (38.46) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 1 (7.69) | 2.80 |
Authors | Studies |
---|---|
Azuma, F | 1 |
Nokura, K | 1 |
Kako, T | 1 |
Kobayashi, D | 1 |
Yoshimura, T | 1 |
Wada, K | 1 |
Kalaci, A | 1 |
Duru, M | 1 |
Karazincir, S | 1 |
Sevinç, TT | 1 |
Kuvandik, G | 1 |
Balci, A | 1 |
Naasan, G | 1 |
Yabroudi, M | 1 |
Rahi, A | 1 |
Mikati, MA | 1 |
ARCANGELI, A | 1 |
DEVADATTA, S | 1 |
Thompson, MD | 1 |
Killoran, A | 1 |
Percy, ME | 1 |
Nezarati, M | 1 |
Cole, DE | 1 |
Hwang, PA | 1 |
Ozyurek, H | 1 |
Turker, H | 1 |
Akbalik, M | 1 |
Bayrak, AO | 1 |
Ince, H | 1 |
Duru, F | 1 |
Heyer, G | 1 |
Simon, M | 1 |
Schell, H | 1 |
Martinjak-Dvorsek, I | 1 |
Gorjup, V | 1 |
Horvat, M | 1 |
Noc, M | 1 |
Reinken, L | 1 |
Houillon, G | 1 |
Samulak, G | 1 |
Houillon, P | 1 |
Kochen, W | 2 |
Feist, D | 1 |
13 other studies available for pyridoxine and Epilepsy, Tonic-Clonic
Article | Year |
---|---|
An Adult Case of Generalized Convulsions Caused by the Ingestion of Ginkgo biloba Seeds with Alcohol.
Topics: Alcoholic Beverages; Epilepsy, Tonic-Clonic; Female; Ginkgo biloba; Humans; Middle Aged; Pyridoxal P | 2020 |
Thoracic spine compression fracture during isoniazid-induced seizures: case report.
Topics: Antidotes; Back Pain; Charcoal; Child; Drug Overdose; Epilepsy, Tonic-Clonic; Female; Fractures, Com | 2008 |
Electroencephalographic changes in pyridoxine-dependant epilepsy: new observations.
Topics: Age of Onset; Electroencephalography; Epilepsies, Partial; Epilepsy, Generalized; Epilepsy, Tonic-Cl | 2009 |
[EPILEPTIC SYNDROMES WITHIN THE FRAMEWORK OF CHRONIC HEADACHE].
Topics: Anticonvulsants; Diencephalon; Endocrinology; Epilepsy; Epilepsy, Absence; Epilepsy, Temporal Lobe; | 1964 |
ISONIAZID-INDUCED ENCEPHALOPATHY.
Topics: Brain Diseases; Drug Therapy; Epilepsy; Epilepsy, Tonic-Clonic; Isoniazid; Peripheral Nervous System | 1965 |
Hyperphosphatasia with neurologic deficit: a pyridoxine-responsive seizure disorder?
Topics: Alkaline Phosphatase; Child, Preschool; Developmental Disabilities; Epilepsy, Tonic-Clonic; Female; | 2006 |
Pyridoxine and pyridostigmine treatment in vincristine-induced neuropathy.
Topics: Antineoplastic Combined Chemotherapy Protocols; Axonal Transport; Blepharoptosis; Child, Preschool; | 2007 |
[Dose-dependent pellagroid skin reaction caused by carbamazepine].
Topics: Anticonvulsants; Biopsy; Carbamazepine; Child; Diagnosis, Differential; Drug Eruptions; Epilepsy, To | 1998 |
Acute isoniazid neurotoxicity during preventive therapy.
Topics: Acute Disease; Adolescent; Antitubercular Agents; Coma; Conscious Sedation; Electroencephalography; | 2000 |
[The effect of hydantoin and succinimide on vitamin B 6 metabolism].
Topics: Child; Child, Preschool; Epilepsy, Absence; Epilepsy, Tonic-Clonic; Humans; Hydantoins; Infant; Pyri | 1973 |
[Apropos of a case of Gayet-Wernicke's encephalopathy in a latent epileptic. Centrophenoxine and thiamine. Electro-clinical contraindications].
Topics: Acetates; Adult; Central Nervous System Stimulants; Epilepsy, Tonic-Clonic; Humans; Hydroxocobalamin | 1968 |
[Tryptophan metabolism in pyridoxine-dependent convulsions].
Topics: Chemistry, Clinical; Child; Child, Preschool; Chromatography, Thin Layer; Epilepsy, Tonic-Clonic; Hu | 1971 |
[Studies of tryptophan metabolism in pyridoxin-dependent convulsions].
Topics: Child, Preschool; Epilepsy, Tonic-Clonic; Humans; Metabolism, Inborn Errors; Pyridoxine; Tryptophan; | 1971 |