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pyridoxine and Eosinophilia-Myalgia Syndrome

pyridoxine has been researched along with Eosinophilia-Myalgia Syndrome in 3 studies

4,5-bis(hydroxymethyl)-2-methylpyridin-3-ol: structure in first source
vitamin B6 : Any member of the group of pyridines that exhibit biological activity against vitamin B6 deficiency. Vitamin B6 deficiency is associated with microcytic anemia, electroencephalographic abnormalities, dermatitis with cheilosis (scaling on the lips and cracks at the corners of the mouth) and glossitis (swollen tongue), depression and confusion, and weakened immune function. Vitamin B6 consists of the vitamers pyridoxine, pyridoxal, and pyridoxamine and their respective 5'-phosphate esters (and includes their corresponding ionized and salt forms).

Eosinophilia-Myalgia Syndrome: A complex systemic syndrome with inflammatory and autoimmune components that affect the skin, fascia, muscle, nerve, blood vessels, lung, and heart. Diagnostic features generally include EOSINOPHILIA, myalgia severe enough to limit usual activities of daily living, and the absence of coexisting infectious, autoimmune or other conditions that may induce eosinophilia. Biopsy of affected tissue reveals a microangiopathy associated with diffuse inflammation involving connective tissue. (From Spitzer et al., J Rheumatol Suppl 1996 Oct;46:73-9; Blackburn WD, Semin Arthritis Rheum 1997 Jun;26(6):788-93)

Research Excerpts

ExcerptRelevanceReference
"To estimate the attack rate for eosinophilia-myalgia syndrome and to identify potential risk factors for illness among patients attending a New York City medical clinic, who purchased L-tryptophan containing products produced exclusively by Showa Denko K."7.68Eosinophilia-myalgia syndrome in patients ingesting a single source of L-tryptophan. ( Friedman, SM; Henning, KJ; Hill, RH; Jean-Baptiste, E; Singh, T, 1993)
"Abnormal metabolism of tryptophan is one of the possible aetiological factors in the L-tryptophan-induced eosinophilia-myalgia syndrome (EMS)."7.68L-tryptophan-induced eosinophilia-myalgia syndrome. II. Partial correction of abnormal tryptophan metabolism by pyridoxine. ( Fathi, M; Mainetti, C; Saurat, JH, 1991)
"To estimate the attack rate for eosinophilia-myalgia syndrome and to identify potential risk factors for illness among patients attending a New York City medical clinic, who purchased L-tryptophan containing products produced exclusively by Showa Denko K."3.68Eosinophilia-myalgia syndrome in patients ingesting a single source of L-tryptophan. ( Friedman, SM; Henning, KJ; Hill, RH; Jean-Baptiste, E; Singh, T, 1993)
"Abnormal metabolism of tryptophan is one of the possible aetiological factors in the L-tryptophan-induced eosinophilia-myalgia syndrome (EMS)."3.68L-tryptophan-induced eosinophilia-myalgia syndrome. II. Partial correction of abnormal tryptophan metabolism by pyridoxine. ( Fathi, M; Mainetti, C; Saurat, JH, 1991)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
McKeon, P1
Swanwick, G1
Manley, P1
Henning, KJ1
Jean-Baptiste, E1
Singh, T1
Hill, RH1
Friedman, SM1
Mainetti, C1
Fathi, M1
Saurat, JH1

Other Studies

3 other studies available for pyridoxine and Eosinophilia-Myalgia Syndrome

ArticleYear
L-tryptophan and the eosinophilia-myalgia syndrome: a clinical and laboratory study.
    Acta psychiatrica Scandinavica, 1994, Volume: 90, Issue:6

    Topics: Antibodies, Antinuclear; Antidepressive Agents; Ascorbic Acid; Diagnosis, Differential; Dose-Respons

1994
Eosinophilia-myalgia syndrome in patients ingesting a single source of L-tryptophan.
    The Journal of rheumatology, 1993, Volume: 20, Issue:2

    Topics: Case-Control Studies; Chromium; Dose-Response Relationship, Drug; Drug Interactions; Eosinophilia-My

1993
L-tryptophan-induced eosinophilia-myalgia syndrome. II. Partial correction of abnormal tryptophan metabolism by pyridoxine.
    Dermatologica, 1991, Volume: 183, Issue:1

    Topics: Adult; Eosinophilia-Myalgia Syndrome; Female; Humans; Hydroxyindoleacetic Acid; Kynurenine; Middle A

1991