Page last updated: 2024-10-20

pyridoxine and Dystonia

pyridoxine has been researched along with Dystonia in 2 studies

4,5-bis(hydroxymethyl)-2-methylpyridin-3-ol: structure in first source
vitamin B6 : Any member of the group of pyridines that exhibit biological activity against vitamin B6 deficiency. Vitamin B6 deficiency is associated with microcytic anemia, electroencephalographic abnormalities, dermatitis with cheilosis (scaling on the lips and cracks at the corners of the mouth) and glossitis (swollen tongue), depression and confusion, and weakened immune function. Vitamin B6 consists of the vitamers pyridoxine, pyridoxal, and pyridoxamine and their respective 5'-phosphate esters (and includes their corresponding ionized and salt forms).

Dystonia: An attitude or posture due to the co-contraction of agonists and antagonist muscles in one region of the body. It most often affects the large axial muscles of the trunk and limb girdles. Conditions which feature persistent or recurrent episodes of dystonia as a primary manifestation of disease are referred to as DYSTONIC DISORDERS. (Adams et al., Principles of Neurology, 6th ed, p77)

Research Excerpts

ExcerptRelevanceReference
"Fourteen patients with spasmodic torticollis and other segmental dystonic syndromes, who were refractory to previous forms of therapy, were selected for treatment with drugs intended to elevate brain gamma-aminobutyric acid (GABA) levels."5.26Effect of L-glutamine and isoniazid on torticollis and segmental dystonia. ( Korein, J; Kupersmith, M; Levidow, L; Lieberman, A, 1981)
"Classical homocystinuria is caused by pathogenic variants in the CBS gene leading to a deficiency of the vitamin B6-dependent enzyme cystathionine beta synthase."1.91Classical homocystinuria presenting with transient basal ganglia pathology and dystonia. ( Averdunk, L; Distelmaier, F; Haack, TB; Klee, D; Thimm, E, 2023)
"Fourteen patients with spasmodic torticollis and other segmental dystonic syndromes, who were refractory to previous forms of therapy, were selected for treatment with drugs intended to elevate brain gamma-aminobutyric acid (GABA) levels."1.26Effect of L-glutamine and isoniazid on torticollis and segmental dystonia. ( Korein, J; Kupersmith, M; Levidow, L; Lieberman, A, 1981)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19901 (50.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's1 (50.00)2.80

Authors

AuthorsStudies
Averdunk, L1
Thimm, E1
Klee, D1
Haack, TB1
Distelmaier, F1
Korein, J1
Lieberman, A1
Kupersmith, M1
Levidow, L1

Other Studies

2 other studies available for pyridoxine and Dystonia

ArticleYear
Classical homocystinuria presenting with transient basal ganglia pathology and dystonia.
    Journal of inherited metabolic disease, 2023, Volume: 46, Issue:6

    Topics: Child; Cystathionine beta-Synthase; Dystonia; Dystonic Disorders; Homocysteine; Homocystinuria; Huma

2023
Effect of L-glutamine and isoniazid on torticollis and segmental dystonia.
    Annals of neurology, 1981, Volume: 10, Issue:3

    Topics: Adult; Diazepam; Drug Therapy, Combination; Dystonia; Glutamine; Humans; Isoniazid; Middle Aged; Pyr

1981