pyridoxine has been researched along with Dyskinesia, Drug-Induced in 8 studies
4,5-bis(hydroxymethyl)-2-methylpyridin-3-ol: structure in first source
vitamin B6 : Any member of the group of pyridines that exhibit biological activity against vitamin B6 deficiency. Vitamin B6 deficiency is associated with microcytic anemia, electroencephalographic abnormalities, dermatitis with cheilosis (scaling on the lips and cracks at the corners of the mouth) and glossitis (swollen tongue), depression and confusion, and weakened immune function. Vitamin B6 consists of the vitamers pyridoxine, pyridoxal, and pyridoxamine and their respective 5'-phosphate esters (and includes their corresponding ionized and salt forms).
Dyskinesia, Drug-Induced: Abnormal movements, including HYPERKINESIS; HYPOKINESIA; TREMOR; and DYSTONIA, associated with the use of certain medications or drugs. Muscles of the face, trunk, neck, and extremities are most commonly affected. Tardive dyskinesia refers to abnormal hyperkinetic movements of the muscles of the face, tongue, and neck associated with the use of neuroleptic agents (see ANTIPSYCHOTIC AGENTS). (Adams et al., Principles of Neurology, 6th ed, p1199)
| Excerpt | Relevance | Reference |
|---|---|---|
| " This review summarises that available pharmacokinetic data involving levodopa, especially as it relates to therapeutic response of parkinsonian patients." | 2.35 | Clinical pharmacokinetics of levodopa in parkinson's disease. ( Bianchine, JR; Shaw, GM, 1976) |
| "Pyridoxine has been reported to attenuate the severity of levodopa-induced dyskinesias in patients with Parkinson's disease and it is suggested that pyridoxine supplementation should be considered in psychiatric patients with drug-induced movement disorders including persistent Parkinsonism." | 1.28 | Pyridoxine improves drug-induced parkinsonism and psychosis in a schizophrenic patient. ( Pardeshi, R; Sandyk, R, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (50.00) | 18.7374 |
| 1990's | 3 (37.50) | 18.2507 |
| 2000's | 1 (12.50) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Neumann, NU | 1 |
| Lerner, V | 2 |
| Liberman, M | 1 |
| Miodownik, C | 1 |
| Kaptsan, A | 1 |
| Cohen, H | 1 |
| Matar, M | 1 |
| Loewenthal, U | 1 |
| Kotler, M | 1 |
| Campanini, T | 1 |
| Catalano, A | 1 |
| De Risio, C | 1 |
| Forino, V | 1 |
| DeVeaugh-Geiss, J | 1 |
| Manion, L | 1 |
| Bianchine, JR | 1 |
| Shaw, GM | 1 |
| Dommisse, J | 1 |
| Sandyk, R | 1 |
| Pardeshi, R | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Randomized Controlled Trial of Pyridoxine for Tardive Dyskinesia[NCT03287778] | 17 participants (Actual) | Interventional | 2017-12-01 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for pyridoxine and Dyskinesia, Drug-Induced
| Article | Year |
|---|---|
Clinical pharmacokinetics of levodopa in parkinson's disease.
Topics: Carboxy-Lyases; Cardiovascular Diseases; Dopamine; Dose-Response Relationship, Drug; Dyskinesia, Dru | 1976 |
2 trials available for pyridoxine and Dyskinesia, Drug-Induced
| Article | Year |
|---|---|
Vitamin B(6) in the treatment of tardive dyskinesia: a double-blind, placebo-controlled, crossover study.
Topics: Adult; Aged; Cross-Over Studies; Double-Blind Method; Dyskinesia, Drug-Induced; Female; Hospitalizat | 2001 |
High-dose pyridoxine in tardive dyskinesia.
Topics: Aged; Clinical Trials as Topic; Drug Evaluation; Dyskinesia, Drug-Induced; Humans; Male; Middle Aged | 1978 |
5 other studies available for pyridoxine and Dyskinesia, Drug-Induced
| Article | Year |
|---|---|
[Drug therapy in tardive dyskinesia].
Topics: Diagnosis, Differential; Dopamine Antagonists; Dyskinesia, Drug-Induced; Humans; Lithium; Methyldopa | 1980 |
Movement disorders and psychotic symptoms treated with pyridoxine: a case report.
Topics: Adult; Antipsychotic Agents; Dyskinesia, Drug-Induced; Humans; Male; Movement Disorders; Psychotic D | 1998 |
[Tardive dyskinesia. Synthetic-critical review and case contribution].
Topics: Adult; Aged; Baclofen; Dyskinesia, Drug-Induced; Female; Humans; Iatrogenic Disease; Male; Mental Di | 1977 |
Nutritional treatment of tardive dyskinesia.
Topics: Dyskinesia, Drug-Induced; Humans; Niacin; Orthomolecular Therapy; Phosphatidylcholines; Pyridoxine; | 1991 |
Pyridoxine improves drug-induced parkinsonism and psychosis in a schizophrenic patient.
Topics: Adult; Dyskinesia, Drug-Induced; Humans; Male; Parkinson Disease, Secondary; Pyridoxine; Schizophren | 1990 |