pyridoxine has been researched along with Dysesthesia in 12 studies
4,5-bis(hydroxymethyl)-2-methylpyridin-3-ol: structure in first source
vitamin B6 : Any member of the group of pyridines that exhibit biological activity against vitamin B6 deficiency. Vitamin B6 deficiency is associated with microcytic anemia, electroencephalographic abnormalities, dermatitis with cheilosis (scaling on the lips and cracks at the corners of the mouth) and glossitis (swollen tongue), depression and confusion, and weakened immune function. Vitamin B6 consists of the vitamers pyridoxine, pyridoxal, and pyridoxamine and their respective 5'-phosphate esters (and includes their corresponding ionized and salt forms).
| Excerpt | Relevance | Reference |
|---|---|---|
| "The limiting toxicity of low dose continuous infusion 5-fluorouracil (200-300 mg/m2/day) is often palmar-plantar erythrodysesthesia (PPE)." | 7.68 | Pyridoxine therapy for palmar-plantar erythrodysesthesia associated with continuous 5-fluorouracil infusion. ( Dahlberg, S; Fabian, CJ; Giri, S; Molina, R; Slavik, M; Stephens, R, 1990) |
| "The limiting toxicity of low dose continuous infusion 5-fluorouracil (200-300 mg/m2/day) is often palmar-plantar erythrodysesthesia (PPE)." | 3.68 | Pyridoxine therapy for palmar-plantar erythrodysesthesia associated with continuous 5-fluorouracil infusion. ( Dahlberg, S; Fabian, CJ; Giri, S; Molina, R; Slavik, M; Stephens, R, 1990) |
| "The exact prevalence of vitamin B6 deficiency related to neurological manifestations has not been previously reported." | 1.31 | Vitamin B6 deficiency in elderly patients on chronic peritoneal dialysis. ( Kanno, Y; Moriwaki, K; Nakamoto, H; Okada, H; Suzuki, H, 2000) |
| "We report peripheral paresthesias that occurred in a 39-year-old female during five years of amitriptyline administration." | 1.26 | Amitriptyline-related peripheral neuropathy relieved during pyridoxine hydrochloride administration. ( Fredericks, S; Huff, MR; Meadows, GG, 1982) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (66.67) | 18.7374 |
| 1990's | 2 (16.67) | 18.2507 |
| 2000's | 2 (16.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| REZNIK, SE | 1 |
| VILDERMAN, AM | 1 |
| Rossi, D | 1 |
| Catalano, G | 1 |
| Meadows, GG | 1 |
| Huff, MR | 1 |
| Fredericks, S | 1 |
| Vukelja, SJ | 1 |
| Baker, WJ | 1 |
| Burris, HA | 1 |
| Keeling, JH | 1 |
| Von Hoff, D | 1 |
| Moriwaki, K | 1 |
| Kanno, Y | 1 |
| Nakamoto, H | 1 |
| Okada, H | 1 |
| Suzuki, H | 1 |
| Kellner, H | 1 |
| Fabian, CJ | 1 |
| Molina, R | 1 |
| Slavik, M | 1 |
| Dahlberg, S | 1 |
| Giri, S | 1 |
| Stephens, R | 1 |
| Ramilo, O | 1 |
| Kinane, BT | 1 |
| McCracken, GH | 1 |
| Dalton, K | 1 |
| Dalton, MJ | 1 |
| Morris, JS | 1 |
| Ajdukiewicz, AB | 1 |
| Read, AE | 1 |
| Shub, C | 1 |
| Salmonsen, PC | 1 |
| Jordan, JE | 1 |
| Hofmann, MA | 1 |
| Alexander, BB | 1 |
| Raskin, NH | 1 |
| Fishman, RA | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Multicentre Randomized Phase II Study of Neoadjuvant Trastuzumab Plus Docetaxel With and Without Bevacizumab and Trastuzumab Plus Docetaxel Plus Non-pegylated Liposome-encapsulated Doxorubicin (NPLD) With and Without Bevacizumab in HER2-positive Early Bre[NCT01367028] | Phase 2 | 100 participants (Actual) | Interventional | 2011-06-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 trial available for pyridoxine and Dysesthesia
| Article | Year |
|---|---|
[Treatment of cerebral degenerative symptoms due to age. Double blind trial on the effect of Juston (author's transl)].
Topics: Activities of Daily Living; Aged; Aging; Ascorbic Acid; Cachexia; Central Nervous System Diseases; D | 1975 |
11 other studies available for pyridoxine and Dysesthesia
| Article | Year |
|---|---|
[USE OF PYRIDOXINE IN THE TREATMENT OF SIDE EFFECTS OF ANTITUBERCULAR AGENTS].
Topics: Antitubercular Agents; Cycloserine; Depression; Drug Therapy; Eye Manifestations; Isoniazid; Paresth | 1963 |
Pyridoxine as prophylactic therapy for palmar-plantar erythrodysesthesia associated with administration of pegylated liposomal doxorubicin (caelyx): a single-center experience.
Topics: Administration, Oral; Antibiotics, Antineoplastic; Clinical Trials as Topic; Doxorubicin; Erythema; | 2007 |
Amitriptyline-related peripheral neuropathy relieved during pyridoxine hydrochloride administration.
Topics: Adult; Amitriptyline; Humans; Lithium; Male; Paresthesia; Peripheral Nervous System Diseases; Pyrido | 1982 |
Pyridoxine therapy for palmar-plantar erythrodysesthesia associated with taxotere.
Topics: Antineoplastic Agents, Phytogenic; Docetaxel; Erythema; Female; Foot Dermatoses; Hand Dermatoses; Hu | 1993 |
Vitamin B6 deficiency in elderly patients on chronic peritoneal dialysis.
Topics: Adolescent; Adult; Age Factors; Aged; Female; Humans; Male; Middle Aged; Paresthesia; Peritoneal Dia | 2000 |
Pyridoxine therapy for palmar-plantar erythrodysesthesia associated with continuous 5-fluorouracil infusion.
Topics: Colonic Neoplasms; Edema; Erythema; Fluorouracil; Follow-Up Studies; Foot Dermatoses; Hand Dermatose | 1990 |
Chloramphenicol neurotoxicity.
Topics: Child; Chloramphenicol; Humans; Male; Optic Neuritis; Paresthesia; Pyridoxine; Time Factors; Visual | 1988 |
Characteristics of pyridoxine overdose neuropathy syndrome.
Topics: Dose-Response Relationship, Drug; Female; Humans; Hyperesthesia; Middle Aged; Nervous System Disease | 1987 |
Neurological disorders and adult coeliac disease.
Topics: Action Potentials; Adult; Aged; Anemia; Calcium; Celiac Disease; Depression; Diet; Epilepsy; Female; | 1970 |
Safety of INH chemoprophylaxis in aviation personnel.
Topics: Adult; Aerospace Medicine; Alanine Transaminase; Aspartate Aminotransferases; Electroencephalography | 1971 |
Pyridoxine-deficiency neuropathy due to hydralazine.
Topics: Female; Humans; Hydralazine; Hypertension; Middle Aged; Paresthesia; Pyridoxine; Tryptophan; Urine; | 1965 |