pyridoxine has been researched along with Drug Withdrawal Symptoms in 15 studies
4,5-bis(hydroxymethyl)-2-methylpyridin-3-ol: structure in first source
vitamin B6 : Any member of the group of pyridines that exhibit biological activity against vitamin B6 deficiency. Vitamin B6 deficiency is associated with microcytic anemia, electroencephalographic abnormalities, dermatitis with cheilosis (scaling on the lips and cracks at the corners of the mouth) and glossitis (swollen tongue), depression and confusion, and weakened immune function. Vitamin B6 consists of the vitamers pyridoxine, pyridoxal, and pyridoxamine and their respective 5'-phosphate esters (and includes their corresponding ionized and salt forms).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Sixty patients, recognized as chronic alcoholics on the grounds of the case history and with a score above 11 of the Munich Alcoholism Test (MALT) have been treated with metadoxine or placebo for thirty days according to a double blind randomized design." | 9.07 | [Therapeutic use of metadoxine in chronic alcoholism. Double blind study of patients in a department of general medicine]. ( Breda, A; Dotta, C; Gelso, E; Moretto, F; Pace, M; Rizzo, A; Sanzuol, F; Tossani, C, 1993) |
| "Pyridoxine-dependent epilepsy (PDE) is an autosomal recessive disorder characterized by early onset and recurrent seizures that can be controlled by a high dose of pyridoxine." | 7.81 | Seizure recurrence following pyridoxine withdrawal in a patient with pyridoxine-dependent epilepsy. ( Iai, M; Osaka, H; Shimbo, H; Tamaura, M; Yamashita, S, 2015) |
| "Sixty patients, recognized as chronic alcoholics on the grounds of the case history and with a score above 11 of the Munich Alcoholism Test (MALT) have been treated with metadoxine or placebo for thirty days according to a double blind randomized design." | 5.07 | [Therapeutic use of metadoxine in chronic alcoholism. Double blind study of patients in a department of general medicine]. ( Breda, A; Dotta, C; Gelso, E; Moretto, F; Pace, M; Rizzo, A; Sanzuol, F; Tossani, C, 1993) |
| "Pyridoxine-dependent epilepsy (PDE) is an autosomal recessive disorder characterized by early onset and recurrent seizures that can be controlled by a high dose of pyridoxine." | 3.81 | Seizure recurrence following pyridoxine withdrawal in a patient with pyridoxine-dependent epilepsy. ( Iai, M; Osaka, H; Shimbo, H; Tamaura, M; Yamashita, S, 2015) |
| "Neonatal seizures, as distinguished from nonconvulsive abnormal movements, are a significant problem in neonatal intensive care units." | 2.37 | Neonatal seizures. ( Bergman, I; Crumrine, P; Painter, MJ, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (60.00) | 18.7374 |
| 1990's | 5 (33.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (6.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Tamaura, M | 1 |
| Shimbo, H | 1 |
| Iai, M | 1 |
| Yamashita, S | 1 |
| Osaka, H | 1 |
| Alhadeff, L | 1 |
| Gualtieri, CT | 1 |
| Lipton, M | 1 |
| Rizzo, A | 1 |
| Breda, A | 1 |
| Moretto, F | 1 |
| Pace, M | 1 |
| Dotta, C | 1 |
| Gelso, E | 2 |
| Sanzuol, F | 1 |
| Tossani, C | 1 |
| South, M | 1 |
| Yoshikawa, H | 1 |
| Abe, T | 1 |
| Oda, Y | 1 |
| Iakovlev, VA | 1 |
| Brenner, A | 1 |
| Wapnir, RA | 1 |
| Campanini, T | 1 |
| Catalano, A | 1 |
| De Risio, C | 1 |
| Forino, V | 1 |
| Siu, PM | 1 |
| West, S | 1 |
| Bogdanove, AJ | 1 |
| Hillbom, ME | 1 |
| Kosunen, AL | 1 |
| Nikander, P | 1 |
| Pösö, AR | 1 |
| Bono, G | 1 |
| Sinforiani, E | 1 |
| Merlo, P | 1 |
| Belloni, G | 1 |
| Soldati, M | 1 |
| Shipman, AJ | 1 |
| Parker, SJ | 1 |
| Painter, MJ | 1 |
| Bergman, I | 1 |
| Crumrine, P | 1 |
| Houillon, G | 1 |
| Samulak, G | 1 |
| Houillon, P | 1 |
| Jancy, J | 1 |
3 reviews available for pyridoxine and Drug Withdrawal Symptoms
| Article | Year |
|---|---|
Toxic effects of water-soluble vitamins.
Topics: Adult; Ascorbic Acid; Child; Dose-Response Relationship, Drug; Drug Interactions; Folic Acid; Humans | 1984 |
Pyridoxine-dependent seizures in an older child.
Topics: Child; Child, Preschool; Electroencephalography; Female; Follow-Up Studies; Humans; Infant; Infant, | 1999 |
Neonatal seizures.
Topics: Adrenoleukodystrophy; Amino Acid Metabolism, Inborn Errors; Ammonia; Anesthetics, Local; Anticonvuls | 1986 |
3 trials available for pyridoxine and Drug Withdrawal Symptoms
| Article | Year |
|---|---|
[Therapeutic use of metadoxine in chronic alcoholism. Double blind study of patients in a department of general medicine].
Topics: Alcoholic Intoxication; Alcoholism; Double-Blind Method; Drug Combinations; Drug Evaluation; Female; | 1993 |
[The treatment of alcoholism with metadoxil].
Topics: Adult; Alcohol Deterrents; Alcoholism; Drug Combinations; Drug Therapy, Combination; Ethanol; Humans | 1999 |
Alcoholic abstinence syndrome: short-term treatment with metadoxine.
Topics: Adult; Anti-Anxiety Agents; Benzodiazepines; Double-Blind Method; Drug Combinations; Ethanol; Humans | 1991 |
9 other studies available for pyridoxine and Drug Withdrawal Symptoms
| Article | Year |
|---|---|
Seizure recurrence following pyridoxine withdrawal in a patient with pyridoxine-dependent epilepsy.
Topics: Aldehyde Dehydrogenase; Anticonvulsants; Brain; Diagnosis, Differential; DNA Mutational Analysis; El | 2015 |
Neonatal seizures after use of pyridoxine in pregnancy.
Topics: Adult; Female; Humans; Infant, Newborn; Pregnancy; Pyridoxine; Seizures; Self Medication; Substance | 1999 |
A pyridoxine-dependent behavioral disorder unmasked by isoniazid.
Topics: Child Behavior Disorders; Child, Preschool; Female; Humans; Hyperkinesis; Isoniazid; Kynurenine; Nia | 1978 |
[Tardive dyskinesia. Synthetic-critical review and case contribution].
Topics: Adult; Aged; Baclofen; Dyskinesia, Drug-Induced; Female; Humans; Iatrogenic Disease; Male; Mental Di | 1977 |
Morphine dependency in rats on a pyridoxine-deficient, a pyridoxine-repleted and a normal chow diet plus pyridoxine injections.
Topics: Animal Feed; Animals; Humans; Injections, Intraperitoneal; Male; Morphine; Naloxone; Pyridoxine; Rat | 1976 |
Effects of single doses and daily administration of pyrithioxine (pyritinolum,NFN, RINN) on the alcohol withdrawal syndrome in rats.
Topics: Animals; Body Weight; Electrolytes; Ethanol; Humans; Male; Pyridoxine; Pyrithioxin; Rats; Seizures; | 1975 |
Toxicity of vitamins.
Topics: Humans; Pyridoxine; Substance Withdrawal Syndrome | 1986 |
[Apropos of a case of Gayet-Wernicke's encephalopathy in a latent epileptic. Centrophenoxine and thiamine. Electro-clinical contraindications].
Topics: Acetates; Adult; Central Nervous System Stimulants; Epilepsy, Tonic-Clonic; Humans; Hydroxocobalamin | 1968 |
Lack of sobering effect of fructose-vitamin tablets.
Topics: Alcohol Drinking; Caffeine; Chlorophyll; Ethanol; Fructose; Humans; Pyridoxine; Substance Withdrawal | 1970 |