pyridoxine has been researched along with Diseases in Twins in 2 studies
4,5-bis(hydroxymethyl)-2-methylpyridin-3-ol: structure in first source
vitamin B6 : Any member of the group of pyridines that exhibit biological activity against vitamin B6 deficiency. Vitamin B6 deficiency is associated with microcytic anemia, electroencephalographic abnormalities, dermatitis with cheilosis (scaling on the lips and cracks at the corners of the mouth) and glossitis (swollen tongue), depression and confusion, and weakened immune function. Vitamin B6 consists of the vitamers pyridoxine, pyridoxal, and pyridoxamine and their respective 5'-phosphate esters (and includes their corresponding ionized and salt forms).
Diseases in Twins: Disorders affecting TWINS, one or both, at any age.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Pyridoxine treatment had no clinical effect but led to a fall in CSF L-dopa and 3-methoxytyrosine and a rise in S-adenosylmethionine." | 1.28 | Aromatic L-amino acid decarboxylase deficiency: clinical features, diagnosis, and treatment of a new inborn error of neurotransmitter amine synthesis. ( Clayton, PT; Hyland, K; Rodeck, C; Surtees, RA, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hyland, K | 2 |
| Surtees, RA | 1 |
| Rodeck, C | 1 |
| Clayton, PT | 2 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| SIngle-Stage, Open-Label, Safety and Efficacy Study of Adeno-Associated Virus Encoding Human Aromatic L-Amino Acid Decarboxylase by Magnetic Resonance MR-guided Infusion Into Midbrain in Pediatric Patients With AADC Deficiency[NCT02852213] | Phase 1 | 31 participants (Anticipated) | Interventional | 2016-07-31 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 other studies available for pyridoxine and Diseases in Twins
| Article | Year |
|---|---|
Aromatic L-amino acid decarboxylase deficiency: clinical features, diagnosis, and treatment of a new inborn error of neurotransmitter amine synthesis.
Topics: Amniotic Fluid; Aromatic-L-Amino-Acid Decarboxylases; Biogenic Amines; Bromocriptine; Cerebrospinal | 1992 |
Aromatic amino acid decarboxylase deficiency in twins.
Topics: Aromatic-L-Amino-Acid Decarboxylases; Bromocriptine; Diseases in Twins; Homovanillic Acid; Humans; H | 1990 |