pyridoxine has been researched along with Diabetic Neuropathies in 14 studies
4,5-bis(hydroxymethyl)-2-methylpyridin-3-ol: structure in first source
vitamin B6 : Any member of the group of pyridines that exhibit biological activity against vitamin B6 deficiency. Vitamin B6 deficiency is associated with microcytic anemia, electroencephalographic abnormalities, dermatitis with cheilosis (scaling on the lips and cracks at the corners of the mouth) and glossitis (swollen tongue), depression and confusion, and weakened immune function. Vitamin B6 consists of the vitamers pyridoxine, pyridoxal, and pyridoxamine and their respective 5'-phosphate esters (and includes their corresponding ionized and salt forms).
Diabetic Neuropathies: Peripheral, autonomic, and cranial nerve disorders that are associated with DIABETES MELLITUS. These conditions usually result from diabetic microvascular injury involving small blood vessels that supply nerves (VASA NERVORUM). Relatively common conditions which may be associated with diabetic neuropathy include third nerve palsy (see OCULOMOTOR NERVE DISEASES); MONONEUROPATHY; mononeuropathy multiplex; diabetic amyotrophy; a painful POLYNEUROPATHY; autonomic neuropathy; and thoracoabdominal neuropathy. (From Adams et al., Principles of Neurology, 6th ed, p1325)
| Excerpt | Relevance | Reference |
|---|---|---|
| " The form of administration (ampoules, dragées), dosage and duration of treatment were left to the individual care-providing physician." | 2.67 | [Therapy of neuropathies with a vitamin B combination. Symptomatic treatment of painful diseases of the peripheral nervous system with a combination preparation of thiamine, pyridoxine and cyanocobalamin]. ( Eckert, M; Schejbal, P, 1992) |
| " The dosage plan for hospitalized patients differed from that for outpatients." | 1.26 | Influence of neurotropic vitamins on the nerve conduction velocity in diabetic neuropathy. ( Tong, HI, 1980) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (42.86) | 18.7374 |
| 1990's | 5 (35.71) | 18.2507 |
| 2000's | 3 (21.43) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cohen, KL | 1 |
| Gorecki, GA | 1 |
| Silverstein, SB | 1 |
| Ebersole, JS | 1 |
| Solomon, LR | 1 |
| Rieder, HP | 1 |
| Berger, W | 1 |
| Fridrich, R | 1 |
| Schneider, LJ | 1 |
| Tong, HI | 1 |
| Straub, RH | 1 |
| Rokitzki, L | 1 |
| Schumacher, T | 1 |
| Hillmann, C | 1 |
| Palitzsch, KD | 1 |
| Schölmerich, J | 1 |
| Stracke, H | 1 |
| Lindemann, A | 1 |
| Federlin, K | 1 |
| Abbas, ZG | 1 |
| Swai, AB | 1 |
| Sadekov, RA | 1 |
| Danilov, AB | 1 |
| Veĭn, AM | 1 |
| Okada, H | 1 |
| Moriwaki, K | 1 |
| Kanno, Y | 1 |
| Sugahara, S | 1 |
| Nakamoto, H | 1 |
| Yoshizawa, M | 1 |
| Suzuki, H | 1 |
| Ambrosch, A | 1 |
| Dierkes, J | 1 |
| Lobmann, R | 1 |
| Kühne, W | 1 |
| König, W | 1 |
| Luley, C | 1 |
| Lehnert, H | 1 |
| Láhoda, F | 1 |
| Eckert, M | 1 |
| Schejbal, P | 1 |
| Miyoshi, T | 1 |
| Goto, I | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Randomized Double Blinded Pilot Study of Oral Thiamine in the Symptomatic Treatment of Painful Diabetic Peripheral Neuropathy[NCT00279266] | 0 participants (Actual) | Interventional | 2006-01-31 | Withdrawn (stopped due to inadequate recruitment) | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
6 trials available for pyridoxine and Diabetic Neuropathies
| Article | Year |
|---|---|
Effect of pyridoxine (vitamin B6) on diabetic patients with peripheral neuropathy.
Topics: Aged; Clinical Trials as Topic; Diabetic Neuropathies; Humans; Middle Aged; Neurologic Examination; | 1984 |
A benfotiamine-vitamin B combination in treatment of diabetic polyneuropathy.
Topics: Administration, Oral; Aged; Capsules; Diabetic Neuropathies; Double-Blind Method; Drug Combinations; | 1996 |
Evaluation of the efficacy of thiamine and pyridoxine in the treatment of symptomatic diabetic peripheral neuropathy.
Topics: Analysis of Variance; Diabetic Neuropathies; Diet Surveys; Double-Blind Method; Drug Monitoring; Dru | 1997 |
[Diabetic polyneuropathy treatment by milgamma-100 preparation].
Topics: Adult; Chelating Agents; Diabetes Mellitus, Type 2; Diabetic Neuropathies; Drug Therapy, Combination | 1998 |
Vitamin B6 supplementation can improve peripheral polyneuropathy in patients with chronic renal failure on high-flux haemodialysis and human recombinant erythropoietin.
Topics: Chronic Disease; Diabetic Neuropathies; Erythropoietin; Female; Glomerulonephritis; Humans; Kidney F | 2000 |
[Therapy of neuropathies with a vitamin B combination. Symptomatic treatment of painful diseases of the peripheral nervous system with a combination preparation of thiamine, pyridoxine and cyanocobalamin].
Topics: Diabetic Neuropathies; Drug Combinations; Female; Humans; Male; Middle Aged; Neuralgia; Neurologic E | 1992 |
8 other studies available for pyridoxine and Diabetic Neuropathies
| Article | Year |
|---|---|
[Oral benfotiamine therapy. Thus you protect the nerves of diabetic patients].
Topics: Administration, Oral; Controlled Clinical Trials as Topic; Diabetes Mellitus, Type 1; Diabetes Melli | 2004 |
[Vitamin status in diabetic neuropathy (thiamine, riboflavin, pyridoxin, cobalamin and tocopherol)].
Topics: Diabetes Complications; Diabetes Mellitus; Diabetic Neuropathies; Diabetic Retinopathy; Female; Huma | 1980 |
Diabetic neuropathy.
Topics: Blood Glucose; Diabetic Neuropathies; Humans; Pyridoxine | 1982 |
Influence of neurotropic vitamins on the nerve conduction velocity in diabetic neuropathy.
Topics: Diabetic Neuropathies; Female; Humans; Male; Middle Aged; Neural Conduction; Pyridoxine; Thiamine; V | 1980 |
[Patients with type-II diabetes mellitus and neuropathy have no deficiency of vitamins A, E, beta-carotene, B1, B2, B6, B12 and folic acid].
Topics: Aged; Avitaminosis; beta Carotene; Carotenoids; Diabetes Mellitus, Type 2; Diabetic Neuropathies; Fe | 1993 |
Relation between homocysteinaemia and diabetic neuropathy in patients with Type 2 diabetes mellitus.
Topics: Adult; Aged; Biomarkers; Blood Glucose; Blood Pressure; Creatinine; Cystatin C; Cystatins; Diabetes | 2001 |
[Disorders of methionine metabolism in polyneuropathies].
Topics: Adult; Alcoholism; Cystathionine; Diabetic Neuropathies; Female; Humans; Male; Metabolic Diseases; M | 1976 |
Serial in vivo determinations of nerve conduction velocity in rat tails. Physiological and pathological changes.
Topics: Animals; Body Temperature; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Disease Models, A | 1973 |