Page last updated: 2024-10-20

pyridoxine and Diabetic Nephropathies

pyridoxine has been researched along with Diabetic Nephropathies in 4 studies

4,5-bis(hydroxymethyl)-2-methylpyridin-3-ol: structure in first source
vitamin B6 : Any member of the group of pyridines that exhibit biological activity against vitamin B6 deficiency. Vitamin B6 deficiency is associated with microcytic anemia, electroencephalographic abnormalities, dermatitis with cheilosis (scaling on the lips and cracks at the corners of the mouth) and glossitis (swollen tongue), depression and confusion, and weakened immune function. Vitamin B6 consists of the vitamers pyridoxine, pyridoxal, and pyridoxamine and their respective 5'-phosphate esters (and includes their corresponding ionized and salt forms).

Diabetic Nephropathies: KIDNEY injuries associated with diabetes mellitus and affecting KIDNEY GLOMERULUS; ARTERIOLES; KIDNEY TUBULES; and the interstitium. Clinical signs include persistent PROTEINURIA, from microalbuminuria progressing to ALBUMINURIA of greater than 300 mg/24 h, leading to reduced GLOMERULAR FILTRATION RATE and END-STAGE RENAL DISEASE.

Research Excerpts

ExcerptRelevanceReference
"This study was designed to investigate the effects of combined administration of lipoic acid and pyridoxine on albuminuria, oxidative stress, blood pressure, serum advanced glycation end-products, nitric oxide (NO), and endothelin-1 in patients with diabetic nephropathy."9.17Effects of combined lipoic acid and pyridoxine on albuminuria, advanced glycation end-products, and blood pressure in diabetic nephropathy. ( Hedayati, M; Hosseinpanah, F; Nafar, M; Noori, N; Tabibi, H, 2013)
"This study was designed to investigate the effects of combined administration of lipoic acid and pyridoxine on albuminuria, oxidative stress, blood pressure, serum advanced glycation end-products, nitric oxide (NO), and endothelin-1 in patients with diabetic nephropathy."5.17Effects of combined lipoic acid and pyridoxine on albuminuria, advanced glycation end-products, and blood pressure in diabetic nephropathy. ( Hedayati, M; Hosseinpanah, F; Nafar, M; Noori, N; Tabibi, H, 2013)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19901 (25.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (75.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Noori, N1
Tabibi, H1
Hosseinpanah, F1
Hedayati, M1
Nafar, M1
Polizzi, FC1
Andican, G2
Çetin, E2
Civelek, S2
Yumuk, V2
Burçak, G2
Candan Polizzi, F1
De Lorenzi, F1

Trials

3 trials available for pyridoxine and Diabetic Nephropathies

ArticleYear
Effects of combined lipoic acid and pyridoxine on albuminuria, advanced glycation end-products, and blood pressure in diabetic nephropathy.
    International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition, 2013, Volume: 83, Issue:2

    Topics: Adult; Aged; Albuminuria; Arginine; Blood Pressure; Creatinine; Diabetic Nephropathies; Double-Blind

2013
Increased DNA-glycation in type 2 diabetic patients: the effect of thiamine and pyridoxine therapy.
    Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association, 2012, Volume: 120, Issue:6

    Topics: Aged; Blood Glucose; Diabetes Mellitus, Type 2; Diabetic Nephropathies; DNA; Female; Glycated Hemogl

2012
Plasma AGE-peptides and C-peptide in early-stage diabetic nephropathy patients on thiamine and pyridoxine therapy.
    Minerva medica, 2013, Volume: 104, Issue:1

    Topics: Aged; Aged, 80 and over; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 2; Diabetic Nephropathies

2013

Other Studies

1 other study available for pyridoxine and Diabetic Nephropathies

ArticleYear
[Action of a taurine-nucleotide-vitamin association on carbohydrate metabolism].
    La Clinica terapeutica, 1971, Jun-15, Volume: 57, Issue:5

    Topics: Adult; Aged; Arteriosclerosis; Biliary Tract Diseases; Carbohydrate Metabolism; Coronary Disease; Di

1971