pyridoxine has been researched along with Diabetes Mellitus, Type 2 in 15 studies
4,5-bis(hydroxymethyl)-2-methylpyridin-3-ol: structure in first source
vitamin B6 : Any member of the group of pyridines that exhibit biological activity against vitamin B6 deficiency. Vitamin B6 deficiency is associated with microcytic anemia, electroencephalographic abnormalities, dermatitis with cheilosis (scaling on the lips and cracks at the corners of the mouth) and glossitis (swollen tongue), depression and confusion, and weakened immune function. Vitamin B6 consists of the vitamers pyridoxine, pyridoxal, and pyridoxamine and their respective 5'-phosphate esters (and includes their corresponding ionized and salt forms).
Diabetes Mellitus, Type 2: A subclass of DIABETES MELLITUS that is not INSULIN-responsive or dependent (NIDDM). It is characterized initially by INSULIN RESISTANCE and HYPERINSULINEMIA; and eventually by GLUCOSE INTOLERANCE; HYPERGLYCEMIA; and overt diabetes. Type II diabetes mellitus is no longer considered a disease exclusively found in adults. Patients seldom develop KETOSIS but often exhibit OBESITY.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Pyridoxine is an important co-factor for many biochemical reactions in cellular metabolism related to the synthesis and catabolism of amino acids, fatty acids, neurotransmitters." | 6.72 | Isolated Pyridoxine Deficiency Presenting as Muscle Spasms in a Patient With Type 2 Diabetes: A Case Report and Literature Review. ( Effiong, U; Zhou, J, 2021) |
| "Pyridoxine is an important co-factor for many biochemical reactions in cellular metabolism related to the synthesis and catabolism of amino acids, fatty acids, neurotransmitters." | 2.72 | Isolated Pyridoxine Deficiency Presenting as Muscle Spasms in a Patient With Type 2 Diabetes: A Case Report and Literature Review. ( Effiong, U; Zhou, J, 2021) |
| "In study II, 41 patients with type 2 diabetes and mild hyperhomocysteinaemia were analysed after 6 months treatment with 5 mg of folic acid or placebo." | 2.72 | No effect of B vitamins on ADMA levels in patients at increased cardiovascular risk. ( Brouwer, CB; Rauwerda, JA; Smulders, YM; Spoelstra-de Man, AM; Stehouwer, CD; Teerlink, T, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (6.67) | 18.7374 |
| 1990's | 5 (33.33) | 18.2507 |
| 2000's | 4 (26.67) | 29.6817 |
| 2010's | 4 (26.67) | 24.3611 |
| 2020's | 1 (6.67) | 2.80 |
| Authors | Studies |
|---|---|
| Zhou, J | 1 |
| Effiong, U | 1 |
| Dzyurkevich, MS | 1 |
| Babkov, DA | 1 |
| Shtyrlin, NV | 1 |
| Mayka, OY | 1 |
| Iksanova, AG | 1 |
| Vassiliev, PM | 1 |
| Balakin, KV | 1 |
| Spasov, AA | 1 |
| Tarasov, VV | 1 |
| Barreto, G | 1 |
| Shtyrlin, YG | 1 |
| Aliev, G | 1 |
| Merigliano, C | 1 |
| Mascolo, E | 1 |
| La Torre, M | 1 |
| Saggio, I | 1 |
| Vernì, F | 1 |
| Polizzi, FC | 1 |
| Andican, G | 2 |
| Çetin, E | 2 |
| Civelek, S | 2 |
| Yumuk, V | 2 |
| Burçak, G | 2 |
| Candan Polizzi, F | 1 |
| Ji, Y | 1 |
| Han, Y | 1 |
| Diao, J | 1 |
| Huang, Y | 1 |
| Chen, Q | 1 |
| Ferro, A | 1 |
| Spoelstra-de Man, AM | 1 |
| Teerlink, T | 1 |
| Brouwer, CB | 1 |
| Rauwerda, JA | 1 |
| Stehouwer, CD | 1 |
| Smulders, YM | 1 |
| Straub, RH | 1 |
| Rokitzki, L | 1 |
| Schumacher, T | 1 |
| Hillmann, C | 1 |
| Palitzsch, KD | 1 |
| Schölmerich, J | 1 |
| Spirichev, VB | 1 |
| Shatniuk, LN | 1 |
| Kodentsova, VM | 1 |
| Vrzhesinskaia, OA | 1 |
| Beketova NA et, AL | 1 |
| Sadekov, RA | 1 |
| Danilov, AB | 1 |
| Veĭn, AM | 1 |
| Chait, A | 1 |
| Malinow, MR | 1 |
| Nevin, DN | 1 |
| Morris, CD | 1 |
| Eastgard, RL | 1 |
| Kris-Etherton, P | 1 |
| Pi-Sunyer, FX | 1 |
| Oparil, S | 1 |
| Resnick, LM | 1 |
| Stern, JS | 1 |
| Haynes, RB | 1 |
| Hatton, DC | 1 |
| Metz, JA | 1 |
| Clark, S | 1 |
| McMahon, M | 1 |
| Holcomb, S | 1 |
| Reusser, ME | 1 |
| Snyder, GW | 1 |
| McCarron, DA | 1 |
| Ambrosch, A | 1 |
| Dierkes, J | 1 |
| Lobmann, R | 1 |
| Kühne, W | 1 |
| König, W | 1 |
| Luley, C | 1 |
| Lehnert, H | 1 |
| Hernández García, P | 1 |
| Martínez Cruz, F | 1 |
| Cayuelas Martínez, T | 1 |
| Solomon, LR | 1 |
| Cohen, K | 1 |
1 review available for pyridoxine and Diabetes Mellitus, Type 2
| Article | Year |
|---|---|
Isolated Pyridoxine Deficiency Presenting as Muscle Spasms in a Patient With Type 2 Diabetes: A Case Report and Literature Review.
Topics: Diabetes Mellitus, Type 2; Diagnosis, Differential; Female; Humans; Middle Aged; Pyridoxine; Spasm; | 2021 |
5 trials available for pyridoxine and Diabetes Mellitus, Type 2
| Article | Year |
|---|---|
Increased DNA-glycation in type 2 diabetic patients: the effect of thiamine and pyridoxine therapy.
Topics: Aged; Blood Glucose; Diabetes Mellitus, Type 2; Diabetic Nephropathies; DNA; Female; Glycated Hemogl | 2012 |
Plasma AGE-peptides and C-peptide in early-stage diabetic nephropathy patients on thiamine and pyridoxine therapy.
Topics: Aged; Aged, 80 and over; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 2; Diabetic Nephropathies | 2013 |
No effect of B vitamins on ADMA levels in patients at increased cardiovascular risk.
Topics: Adolescent; Adult; Arginine; Atherosclerosis; Cardiovascular Diseases; Diabetes Mellitus, Type 2; Do | 2006 |
[Diabetic polyneuropathy treatment by milgamma-100 preparation].
Topics: Adult; Chelating Agents; Diabetes Mellitus, Type 2; Diabetic Neuropathies; Drug Therapy, Combination | 1998 |
Increased dietary micronutrients decrease serum homocysteine concentrations in patients at high risk of cardiovascular disease.
Topics: Adult; Aged; Analysis of Variance; Cardiovascular Diseases; Diabetes Mellitus, Type 2; Diet; Female; | 1999 |
9 other studies available for pyridoxine and Diabetes Mellitus, Type 2
| Article | Year |
|---|---|
Pyridoxine dipharmacophore derivatives as potent glucokinase activators for the treatment of type 2 diabetes mellitus.
Topics: Allosteric Site; Animals; Diabetes Mellitus, Type 2; Enzyme Activators; Female; Glucokinase; Humans; | 2017 |
Protective role of vitamin B6 (PLP) against DNA damage in Drosophila models of type 2 diabetes.
Topics: Animals; Body Size; Brain; Chromosome Aberrations; Diabetes Mellitus, Experimental; Diabetes Mellitu | 2018 |
Rabbit aortic endothelial dysfunction by low-density lipoprotein is attenuated by L-arginine, L-ascorbate and pyridoxine.
Topics: Adult; Animals; Aorta, Thoracic; Arginine; Ascorbic Acid; Diabetes Mellitus, Type 2; Dose-Response R | 2003 |
[Oral benfotiamine therapy. Thus you protect the nerves of diabetic patients].
Topics: Administration, Oral; Controlled Clinical Trials as Topic; Diabetes Mellitus, Type 1; Diabetes Melli | 2004 |
[Patients with type-II diabetes mellitus and neuropathy have no deficiency of vitamins A, E, beta-carotene, B1, B2, B6, B12 and folic acid].
Topics: Aged; Avitaminosis; beta Carotene; Carotenoids; Diabetes Mellitus, Type 2; Diabetic Neuropathies; Fe | 1993 |
[Prophylactic food products in a diet of patients with diabetes++ mellitus, type II].
Topics: Adult; Ascorbic Acid; beta Carotene; Blood Pressure; Diabetes Mellitus, Type 2; Diet, Sodium-Restric | 1997 |
Relation between homocysteinaemia and diabetic neuropathy in patients with Type 2 diabetes mellitus.
Topics: Adult; Aged; Biomarkers; Blood Glucose; Blood Pressure; Creatinine; Cystatin C; Cystatins; Diabetes | 2001 |
[PPD and chemoprophylaxis in diabetes mellitus].
Topics: Adult; Aged; Aged, 80 and over; Diabetes Complications; Diabetes Mellitus, Type 1; Diabetes Mellitus | 1992 |
Erythrocyte O2 transport and metabolism and effects of vitamin B6 therapy in type II diabetes mellitus.
Topics: Animals; Biological Transport; Diabetes Mellitus, Type 2; Double-Blind Method; Erythrocytes; Glycosy | 1989 |