pyridoxine has been researched along with Depressive Disorder in 17 studies
4,5-bis(hydroxymethyl)-2-methylpyridin-3-ol: structure in first source
vitamin B6 : Any member of the group of pyridines that exhibit biological activity against vitamin B6 deficiency. Vitamin B6 deficiency is associated with microcytic anemia, electroencephalographic abnormalities, dermatitis with cheilosis (scaling on the lips and cracks at the corners of the mouth) and glossitis (swollen tongue), depression and confusion, and weakened immune function. Vitamin B6 consists of the vitamers pyridoxine, pyridoxal, and pyridoxamine and their respective 5'-phosphate esters (and includes their corresponding ionized and salt forms).
Depressive Disorder: An affective disorder manifested by either a dysphoric mood or loss of interest or pleasure in usual activities. The mood disturbance is prominent and relatively persistent.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Pyridoxine (Vitamin B6) in essential for the proper metabolism of various neurotransmitters that are considered relevant to the pathophysiology of depression and/or schizophrenia and it has been reported beneficial in ameliorating depressive symptoms as part of major depression, premenstrual syndrome or 'Chinese restaurant syndrome'." | 5.09 | [Antidepressive effect of pyridoxine (vitamin B6) in neuroleptic-treated schizophrenic patients with co-morbid minor depression--preliminary open-label trial]. ( Dorfman-Etrog, P; Munitz, H; Shiloh, R; Weizer, N; Weizman, A, 2001) |
| " (1) The chronic administration of isoniazid for the prevention or treatment of tuberculosis can produce peripheral neuropathy which can be prevented by the concurrent administration of pyridoxine." | 2.36 | Drug-pyridoxal phosphate interactions. ( Al-Sayegh, A; Ebadi, M; Gessert, CF, 1982) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 13 (76.47) | 18.7374 |
| 1990's | 1 (5.88) | 18.2507 |
| 2000's | 3 (17.65) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Almeida, OP | 1 |
| McCaul, K | 1 |
| Hankey, GJ | 1 |
| Norman, P | 1 |
| Jamrozik, K | 1 |
| Flicker, L | 1 |
| Hallert, C | 2 |
| Svensson, M | 1 |
| Tholstrup, J | 1 |
| Hultberg, B | 1 |
| KLEIN, JR | 1 |
| ACUNA, JC | 1 |
| WAARDENBURG, HA | 1 |
| Ebadi, M | 1 |
| Gessert, CF | 1 |
| Al-Sayegh, A | 1 |
| Gualtieri, CT | 1 |
| Golden, RN | 1 |
| Fahs, JJ | 1 |
| Aström, J | 1 |
| Walan, A | 1 |
| Stewart, JW | 1 |
| Harrison, W | 1 |
| Quitkin, F | 1 |
| Baker, H | 1 |
| Nissen, G | 1 |
| Hoes, MJ | 1 |
| Loeffen, T | 1 |
| Vree, TB | 1 |
| Casacchia, M | 1 |
| Boni, B | 1 |
| Meco, G | 1 |
| Holsboer, F | 1 |
| Benkert, O | 2 |
| Demisch, L | 1 |
| Bermond, P | 1 |
| Shiloh, R | 1 |
| Weizman, A | 1 |
| Weizer, N | 1 |
| Dorfman-Etrog, P | 1 |
| Munitz, H | 1 |
| Bell, IR | 1 |
| Edman, JS | 1 |
| Morrow, FD | 1 |
| Marby, DW | 1 |
| Perrone, G | 1 |
| Kayne, HL | 1 |
| Greenwald, M | 1 |
| Cole, JO | 1 |
| Holsboen, F | 1 |
| Meier, L | 1 |
| Kreuz-Kersting, A | 1 |
3 reviews available for pyridoxine and Depressive Disorder
| Article | Year |
|---|---|
Homocysteine and depression in later life.
Topics: Age Factors; Aged; Cohort Studies; Depressive Disorder; Folic Acid; Genetic Predisposition to Diseas | 2008 |
Drug-pyridoxal phosphate interactions.
Topics: Animals; Contraceptives, Oral, Hormonal; Depressive Disorder; Disease; Drug Interactions; Drug Thera | 1982 |
New developments in pediatric psychopharmacology.
Topics: Adolescent; Adult; Aggression; Anorexia Nervosa; Antidepressive Agents, Tricyclic; Autistic Disorder | 1983 |
7 trials available for pyridoxine and Depressive Disorder
| Article | Year |
|---|---|
Clinical trial: B vitamins improve health in patients with coeliac disease living on a gluten-free diet.
Topics: Anxiety; Celiac Disease; Depressive Disorder; Diet, Gluten-Free; Female; Folic Acid; Health Status; | 2009 |
New developments in pediatric psychopharmacology.
Topics: Adolescent; Adult; Aggression; Anorexia Nervosa; Antidepressive Agents, Tricyclic; Autistic Disorder | 1983 |
Reversal of psychopathology in adult coeliac disease with the aid of pyridoxine (vitamin B6).
Topics: Adult; Celiac Disease; Clinical Trials as Topic; Depressive Disorder; Female; Humans; Male; Middle A | 1983 |
Kinetics of L-tryptophan in depressive patients: a possible correlation between the plasma concentrations of L-tryptophan and some psychiatric rating scales.
Topics: Chromatography, High Pressure Liquid; Depressive Disorder; Humans; Kinetics; Psychiatric Status Rati | 1981 |
[Antidepressive effect of pyridoxine (vitamin B6) in neuroleptic-treated schizophrenic patients with co-morbid minor depression--preliminary open-label trial].
Topics: Adult; Antidepressive Agents; Antipsychotic Agents; Comorbidity; Depressive Disorder; Drug Therapy, | 2001 |
Brief communication. Vitamin B1, B2, and B6 augmentation of tricyclic antidepressant treatment in geriatric depression with cognitive dysfunction.
Topics: Aged; Cognition Disorders; Depressive Disorder; Drug Therapy, Combination; Female; Folic Acid; Human | 1992 |
Combined estradiol and vitamin B6 treatment in women with major depression.
Topics: Adult; Aged; Clinical Trials as Topic; Depressive Disorder; Drug Therapy, Combination; Ethinyl Estra | 1985 |
8 other studies available for pyridoxine and Depressive Disorder
| Article | Year |
|---|---|
Depression of heme formation and production of free porphyrin in duck erythrocytes.
Topics: Adenine; Animals; Benzimidazoles; Chloramphenicol; Depression; Depressive Disorder; Ducks; Erythrocy | 1962 |
[THERAPEUTIC APPLICATIONS OF HYDROXOCOBALAMINE, THIAMINE AND PYRIDOXINE IN A CONJOINED FORM].
Topics: Anemia; Child; Depression; Depressive Disorder; Feeding and Eating Disorders; Geriatrics; Humans; Hy | 1963 |
[SUICIDE AFTER PROLONGED USE OF CYCLOSERINE].
Topics: Cycloserine; Depression; Depressive Disorder; Ethionamide; Isoniazid; Pyridoxine; Suicide; Toxicolog | 1964 |
Low B6 levels in depressed outpatients.
Topics: Adult; Aged; Depressive Disorder; Female; Humans; Male; Middle Aged; Outpatients; Pyridoxine; Vitami | 1984 |
[Psychotropic drugs for children].
Topics: Amitriptyline; Anxiety Disorders; Attention Deficit Disorder with Hyperactivity; Benzodiazepines; Ce | 1981 |
Pyridoxine and depression: neuroendocrine aspects.
Topics: Depressive Disorder; Dopamine; Drug Synergism; Drug Therapy, Combination; Humans; Levodopa; Male; Pr | 1982 |
Changes in MAO activity during estrogen treatment of females with endogenous depression.
Topics: Adrenal Glands; Blood Platelets; Depressive Disorder; Estrogens; Ethinyl Estradiol; Female; Humans; | 1983 |
Therapy of side effects of oral contraceptive agents with vitamin B6.
Topics: Contraceptives, Oral; Contraceptives, Oral, Hormonal; Depressive Disorder; Dose-Response Relationshi | 1982 |