Page last updated: 2024-10-20

pyridoxine and Deficiency, Vitamin B 12

pyridoxine has been researched along with Deficiency, Vitamin B 12 in 31 studies

4,5-bis(hydroxymethyl)-2-methylpyridin-3-ol: structure in first source
vitamin B6 : Any member of the group of pyridines that exhibit biological activity against vitamin B6 deficiency. Vitamin B6 deficiency is associated with microcytic anemia, electroencephalographic abnormalities, dermatitis with cheilosis (scaling on the lips and cracks at the corners of the mouth) and glossitis (swollen tongue), depression and confusion, and weakened immune function. Vitamin B6 consists of the vitamers pyridoxine, pyridoxal, and pyridoxamine and their respective 5'-phosphate esters (and includes their corresponding ionized and salt forms).

Research Excerpts

ExcerptRelevanceReference
"Hyperhomocysteinemia refers to an elevated circulating level of the sulfur-containing amino acid homocysteine and has been shown to be a risk factor for vascular disease in the general population."4.80Homocysteine and renal disease. ( Robinson, K; van Guldener, C, 2000)
", folate, cobalamin, or pyridoxine) potentiated by maternal dietary deficiency of these cofactors and by pregnancy."3.70DNA polymorphism-diet-cofactor-development hypothesis and the gene-teratogen model for schizophrenia and other developmental disorders. ( Johnson, WG, 1999)
"Alcoholic hepatitis is the precursor of cirrhosis."1.26Alcoholic hepatitis. ( Leevy, CM; Zetterman, RK, 1976)

Research

Studies (31)

TimeframeStudies, this research(%)All Research%
pre-199018 (58.06)18.7374
1990's9 (29.03)18.2507
2000's3 (9.68)29.6817
2010's1 (3.23)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Altun, H1
Şahin, N1
Belge Kurutaş, E1
Güngör, O1
Daghir, NJ1
Haddad, KS1
Boushey, CJ1
Beresford, SA1
Omenn, GS1
Motulsky, AG1
Naurath, HJ1
Joosten, E1
Riezler, R1
Stabler, SP1
Allen, RH1
Lindenbaum, J1
Ubbink, JB1
Vermaak, WJ1
van der Merwe, A1
Becker, PJ1
Nicolas, JP1
Chango, A1
Koehler, KM1
Pareo-Tubbeh, SL1
Liang, HC1
Romero, LJ1
Baumgartner, RN1
Garry, PJ1
Favier, M1
Hininger, I1
Schwaninger, M1
Ringleb, P1
Winter, R1
Kohl, B1
Fiehn, W1
Rieser, PA1
Walter-Sack, I1
Johnson, WG1
van Guldener, C1
Robinson, K1
Herrmann, W1
Schorr, H1
Bodis, M1
Knapp, JP1
Müller, A1
Stein, G1
Geisel, J1
Ruipérez Cantera, I1
Spirichev, VB1
Leevy, CM1
Zetterman, RK1
Larsson-Cohn, U1
Clements, FW1
Quinones, MA1
El Nakah, A1
Louria, DB1
Baker, H1
Devlin, L1
Mason, JB1
Miller, JW1
Blair, R1
Newsome, F1
Truswell, AS1
Margolis, MG1
Mollin, DL1
MacGibbon, BH1
Rosenberg, LE1
Waxman, S1
Corcino, J1
Herbert, V1
Baerlocher, K1
Pauling, L1
Yachiku, S1
Okawa, T1
Takeuchi, M1
Sonoda, T1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Study on Therapeutic Effect of Treating Mental Stress Induced Myocardial Ischemia With Conventional Therapy for Coronary Heart Disease Combined With Traditional Chinese Medicine :Design and Methods[NCT02135250]120 participants (Anticipated)Interventional2014-01-31Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

11 reviews available for pyridoxine and Deficiency, Vitamin B 12

ArticleYear
A quantitative assessment of plasma homocysteine as a risk factor for vascular disease. Probable benefits of increasing folic acid intakes.
    JAMA, 1995, Oct-04, Volume: 274, Issue:13

    Topics: Arteriosclerosis; Coronary Disease; Female; Folic Acid; Food, Fortified; Homocysteine; Humans; Male;

1995
[Vitamins : B1, B6, B12. Consequences of a deficiency, of excessive vitamins and value of systematic supplementation].
    Journal de gynecologie, obstetrique et biologie de la reproduction, 1997, Volume: 26, Issue:3 Suppl

    Topics: Dietary Supplements; Female; Humans; Nutritional Requirements; Pregnancy; Pregnancy Complications; P

1997
Homocysteine and renal disease.
    Seminars in thrombosis and hemostasis, 2000, Volume: 26, Issue:3

    Topics: Adult; Arteriosclerosis; Cardiovascular Diseases; Case-Control Studies; Child; Endothelium, Vascular

2000
[Hereditary disorders of metabolism and function of vitamins].
    Pediatriia, 1975, Issue:7

    Topics: Avitaminosis; Biological Transport, Active; Humans; Metabolism, Inborn Errors; Pyridoxine; Thiamine;

1975
Oral contraceptives and vitamins: a review.
    American journal of obstetrics and gynecology, 1975, Jan-01, Volume: 121, Issue:1

    Topics: Ascorbic Acid; Contraceptives, Oral; Depression; Estradiol Congeners; Female; Folic Acid; Folic Acid

1975
The effects of vitamins B12, B6, and folate on blood homocysteine levels.
    Annals of the New York Academy of Sciences, 1992, Sep-30, Volume: 669

    Topics: Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Pyridoxine; Vitamin B 12; Vitamin B 12 Defi

1992
Involvement of water-soluble vitamins in diseases of swine.
    Journal of animal science, 1985, Volume: 60, Issue:6

    Topics: Animals; Ascorbic Acid; Ascorbic Acid Deficiency; Biotin; Choline; Choline Deficiency; Folic Acid; F

1985
[Vitamin therapy in ophthalmology].
    Oftalmologicheskii zhurnal, 1972, Volume: 27, Issue:8

    Topics: Ascorbic Acid; Drug Synergism; Eye Diseases; Fatty Acids, Essential; Flavonoids; Humans; Niacinamide

1972
Sideroblastic and megaloblastic anaemias.
    British journal of haematology, 1972, Volume: 23

    Topics: Anemia, Macrocytic; Anemia, Sideroblastic; Animals; Biological Assay; Erythrocyte Count; Erythrocyte

1972
Inherited aminoacidopathies demonstrating vitamin dependency.
    The New England journal of medicine, 1969, Jul-17, Volume: 281, Issue:3

    Topics: Adult; Amino Acid Metabolism, Inborn Errors; Child; Humans; Infant; Pyridoxine; Vitamin B 12; Vitami

1969
Aggravation or initiation of megaloblastosis by amino acids in the diet.
    JAMA, 1970, Oct-05, Volume: 214, Issue:1

    Topics: Amino Acids; Anemia, Pernicious; Cell Nucleus; Diet; DNA; Erythrocytes; Folic Acid; Folic Acid Defic

1970

Trials

2 trials available for pyridoxine and Deficiency, Vitamin B 12

ArticleYear
Effects of vitamin B12, folate, and vitamin B6 supplements in elderly people with normal serum vitamin concentrations.
    Lancet (London, England), 1995, Jul-08, Volume: 346, Issue:8967

    Topics: Aged; Aged, 80 and over; Avitaminosis; Citrates; Cystathionine; Double-Blind Method; Female; Folic A

1995
Vitamin B-12, vitamin B-6, and folate nutritional status in men with hyperhomocysteinemia.
    The American journal of clinical nutrition, 1993, Volume: 57, Issue:1

    Topics: Adult; Aged; Cardiovascular Diseases; Cystathionine beta-Synthase; Dose-Response Relationship, Drug;

1993

Other Studies

18 other studies available for pyridoxine and Deficiency, Vitamin B 12

ArticleYear
Homocysteine, Pyridoxine, Folate and Vitamin B12 Levels in Children with Attention Deficit Hyperactivity Disorder.
    Psychiatria Danubina, 2018, Volume: 30, Issue:3

    Topics: Attention Deficit Disorder with Hyperactivity; Behavior Rating Scale; Child; Enzyme-Linked Immunosor

2018
Vitamin B6 in the etiology of gizzard erosion in growing chickens.
    Poultry science, 1981, Volume: 60, Issue:5

    Topics: Animals; Chickens; Folic Acid Deficiency; Gizzard, Avian; Male; Poultry Diseases; Pyridoxine; Stomac

1981
[Deregulation of homocysteine metabolism and consequences for the vascular system].
    Bulletin de l'Academie nationale de medecine, 1997, Volume: 181, Issue:2

    Topics: Folic Acid; Homocysteine; Humans; Pyridoxine; Vascular Diseases; Vitamin B 12 Deficiency

1997
Some vitamin sources relating to plasma homocysteine provide not only folate but also vitamins B-12 and B-6.
    The Journal of nutrition, 1997, Volume: 127, Issue:8

    Topics: Aged; Diet; Female; Folic Acid; Food, Fortified; Homocysteine; Humans; Male; Pyridoxine; Vitamin B 1

1997
Elevated plasma concentrations of homocysteine in antiepileptic drug treatment.
    Epilepsia, 1999, Volume: 40, Issue:3

    Topics: Age Factors; Ambulatory Care; Anticonvulsants; Carbamazepine; Convulsants; Depression, Chemical; Epi

1999
DNA polymorphism-diet-cofactor-development hypothesis and the gene-teratogen model for schizophrenia and other developmental disorders.
    American journal of medical genetics, 1999, Aug-20, Volume: 88, Issue:4

    Topics: Alleles; Brain; Diet; Female; Folic Acid; Folic Acid Deficiency; Genetic Linkage; Genotype; Humans;

1999
Role of homocysteine, cystathionine and methylmalonic acid measurement for diagnosis of vitamin deficiency in high-aged subjects.
    European journal of clinical investigation, 2000, Volume: 30, Issue:12

    Topics: Adult; Aged; Cystathionine; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Kidney;

2000
[Healing with vitamins].
    Revista clinica espanola, 2001, Volume: 201, Issue:2

    Topics: Age Factors; Aged; Anemia, Pernicious; Female; Gastrectomy; Humans; Male; Middle Aged; Pyridoxine; R

2001
Editorial:vitamins and the pill.
    Lancet (London, England), 1975, Mar-08, Volume: 1, Issue:7906

    Topics: Ascorbic Acid; Ascorbic Acid Deficiency; Avitaminosis; Contraceptives, Oral; Female; Humans; Pyridox

1975
Alcoholic hepatitis.
    American family physician, 1976, Volume: 13, Issue:6

    Topics: Alcoholism; Anemia; Animals; Diet; Ethanol; Hepatitis; Humans; Lymphocyte Activation; Macrophage Mig

1976
Nutrition 7. Vitamin and mineral supplementation.
    The Medical journal of Australia, 1975, May-10, Volume: 1, Issue:19

    Topics: Adult; Aged; Ascorbic Acid; Ascorbic Acid Deficiency; Burns; Child; Contraceptives, Oral; Depression

1975
A preliminary study of circulating vitamins in a Puerto Rican migrant farm population in New Jersey.
    American journal of public health, 1976, Volume: 66, Issue:2

    Topics: Adult; Agriculture; Humans; Male; New Jersey; Puerto Rico; Pyridoxine; Transients and Migrants; Vita

1976
Tropical macrocytic anaemia.
    Lancet (London, England), 1986, Jan-11, Volume: 1, Issue:8472

    Topics: Anemia, Macrocytic; Female; Humans; India; Pregnancy; Pregnancy Complications, Hematologic; Pyridoxi

1986
ABC of nutrition. Vitamins II.
    British medical journal (Clinical research ed.), 1985, Oct-19, Volume: 291, Issue:6502

    Topics: Ascorbic Acid; Ascorbic Acid Deficiency; Avitaminosis; Folic Acid; Folic Acid Deficiency; Humans; Py

1985
Editorial: Vitamins and the pill.
    Canadian Medical Association journal, 1974, Aug-03, Volume: 111, Issue:3

    Topics: Anemia, Macrocytic; Ascorbic Acid; Ascorbic Acid Deficiency; Contraceptives, Oral; Depression; Femal

1974
[On the importance of vitamins in congenital metabolic disorders and in the vitamin dependency syndrome].
    Schweizerische Rundschau fur Medizin Praxis = Revue suisse de medecine Praxis, 1971, Jun-15, Volume: 60, Issue:24

    Topics: Avitaminosis; Humans; Metabolism, Inborn Errors; Pyridoxine; Thiamine; Vitamin B 12 Deficiency; Vita

1971
Orthomolecular psychiatry. Varying the concentrations of substances normally present in the human body may control mental disease.
    Science (New York, N.Y.), 1968, Apr-19, Volume: 160, Issue:3825

    Topics: Aminobenzoates; Biological Evolution; Blood-Brain Barrier; Brain; Brain Diseases; Culture Media; Die

1968
[Studies on the etiology of urolithiasis: effects of vitamin B6 and vitamin B1 on urinary oxalate excretion].
    Hinyokika kiyo. Acta urologica Japonica, 1969, Volume: 15, Issue:5

    Topics: Adolescent; Adult; Animals; Humans; Male; Middle Aged; Oxalates; Pyridoxine; Rats; Thiamine; Urinary

1969