pyridoxine has been researched along with Decreased Muscle Tone in 5 studies
4,5-bis(hydroxymethyl)-2-methylpyridin-3-ol: structure in first source
vitamin B6 : Any member of the group of pyridines that exhibit biological activity against vitamin B6 deficiency. Vitamin B6 deficiency is associated with microcytic anemia, electroencephalographic abnormalities, dermatitis with cheilosis (scaling on the lips and cracks at the corners of the mouth) and glossitis (swollen tongue), depression and confusion, and weakened immune function. Vitamin B6 consists of the vitamers pyridoxine, pyridoxal, and pyridoxamine and their respective 5'-phosphate esters (and includes their corresponding ionized and salt forms).
| Excerpt | Relevance | Reference |
|---|---|---|
| "We report intermittent seizures, lethargy, and Cohen's syndrome in a 4-year-old girl with hyper-beta-alaninemia and a partial deficiency of beta-alanyl-alpha-ketoglutarate transaminase (AKT)." | 7.69 | Pyridoxine-responsive hyper-beta-alaninemia associated with Cohen's syndrome. ( Barton, NW; Bernardini, I; Brady, RO; Higgins, JJ; Kaneski, CR, 1994) |
| "We report intermittent seizures, lethargy, and Cohen's syndrome in a 4-year-old girl with hyper-beta-alaninemia and a partial deficiency of beta-alanyl-alpha-ketoglutarate transaminase (AKT)." | 3.69 | Pyridoxine-responsive hyper-beta-alaninemia associated with Cohen's syndrome. ( Barton, NW; Bernardini, I; Brady, RO; Higgins, JJ; Kaneski, CR, 1994) |
| "Early onset hypotonia, oculogyric crises, and autonomic symptoms such as excessive sweating, nasal congestion and profuse nasal, and oropharyngeal secretions, were common in our patients." | 1.56 | The genetic and clinical characteristics of aromatic L-amino acid decarboxylase deficiency in mainland China. ( Bao, X; Chen, Y; Wang, J; Wen, Y; Zhang, Q, 2020) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (20.00) | 18.7374 |
| 1990's | 2 (40.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (20.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wen, Y | 1 |
| Wang, J | 1 |
| Zhang, Q | 1 |
| Chen, Y | 1 |
| Bao, X | 1 |
| Higgins, JJ | 1 |
| Kaneski, CR | 1 |
| Bernardini, I | 1 |
| Brady, RO | 1 |
| Barton, NW | 1 |
| Maller, A | 1 |
| Hyland, K | 1 |
| Milstien, S | 1 |
| Biaggioni, I | 1 |
| Butler, IJ | 1 |
| Grillo, E | 1 |
| da Silva, RJ | 1 |
| Barbato, JH | 1 |
| Kroll, JS | 1 |
5 other studies available for pyridoxine and Decreased Muscle Tone
| Article | Year |
|---|---|
The genetic and clinical characteristics of aromatic L-amino acid decarboxylase deficiency in mainland China.
Topics: Alleles; Amino Acid Metabolism, Inborn Errors; Aromatic-L-Amino-Acid Decarboxylases; China; Cohort S | 2020 |
Pyridoxine-responsive hyper-beta-alaninemia associated with Cohen's syndrome.
Topics: 4-Aminobutyrate Transaminase; Abnormalities, Multiple; beta-Alanine; Child; Female; Humans; Intellec | 1994 |
Aromatic L-amino acid decarboxylase deficiency: clinical features, diagnosis, and treatment of a second family.
Topics: 5-Hydroxytryptophan; Amino Acids, Cyclic; Aromatic-L-Amino-Acid Decarboxylases; Biogenic Monoamines; | 1997 |
Pyridoxine-dependent seizures responding to extremely low-dose pyridoxine.
Topics: Age Factors; Body Weight; Coma; Confounding Factors, Epidemiologic; Developmental Disabilities; Drug | 2001 |
Pyridoxine for neonatal seizures: an unexpected danger.
Topics: Electroencephalography; Evoked Potentials; Humans; Infant, Newborn; Male; Muscle Hypotonia; Pyridoxi | 1985 |